ID   WHIA_TROWT              Reviewed;         319 AA.
AC   Q83MY5;
DT   26-MAY-2009, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2003, sequence version 1.
DT   25-MAY-2022, entry version 99.
DE   RecName: Full=Probable cell division protein WhiA {ECO:0000255|HAMAP-Rule:MF_01420};
GN   Name=whiA {ECO:0000255|HAMAP-Rule:MF_01420}; OrderedLocusNames=TWT_298;
OS   Tropheryma whipplei (strain Twist) (Whipple's bacillus).
OC   Bacteria; Actinobacteria; Micrococcales; Tropherymataceae; Tropheryma.
OX   NCBI_TaxID=203267;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Twist;
RX   PubMed=12902375; DOI=10.1101/gr.1474603;
RA   Raoult D., Ogata H., Audic S., Robert C., Suhre K., Drancourt M.,
RA   Claverie J.-M.;
RT   "Tropheryma whipplei twist: a human pathogenic Actinobacteria with a
RT   reduced genome.";
RL   Genome Res. 13:1800-1809(2003).
CC   -!- FUNCTION: Involved in cell division and chromosome segregation.
CC       {ECO:0000255|HAMAP-Rule:MF_01420}.
CC   -!- SIMILARITY: Belongs to the WhiA family. {ECO:0000255|HAMAP-
CC       Rule:MF_01420}.
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DR   EMBL; AE014184; AAO44395.1; -; Genomic_DNA.
DR   RefSeq; WP_011096421.1; NC_004572.3.
DR   AlphaFoldDB; Q83MY5; -.
DR   SMR; Q83MY5; -.
DR   STRING; 203267.TWT_298; -.
DR   EnsemblBacteria; AAO44395; AAO44395; TWT_298.
DR   GeneID; 67388250; -.
DR   KEGG; twh:TWT_298; -.
DR   eggNOG; COG1481; Bacteria.
DR   HOGENOM; CLU_053282_0_0_11; -.
DR   OMA; CDAEAAW; -.
DR   OrthoDB; 1634356at2; -.
DR   Proteomes; UP000002200; Chromosome.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0051301; P:cell division; IEA:UniProtKB-UniRule.
DR   GO; GO:0043937; P:regulation of sporulation; IEA:InterPro.
DR   Gene3D; 3.10.28.10; -; 1.
DR   HAMAP; MF_01420; HTH_type_WhiA; 1.
DR   InterPro; IPR027434; Homing_endonucl.
DR   InterPro; IPR018478; Sporu_reg_WhiA_N_dom.
DR   InterPro; IPR003802; Sporulation_regulator_WhiA.
DR   InterPro; IPR023054; Sporulation_regulator_WhiA_C.
DR   InterPro; IPR039518; WhiA_LAGLIDADG_dom.
DR   PANTHER; PTHR37307; PTHR37307; 1.
DR   Pfam; PF02650; HTH_WhiA; 1.
DR   Pfam; PF14527; LAGLIDADG_WhiA; 1.
DR   Pfam; PF10298; WhiA_N; 1.
DR   SUPFAM; SSF55608; SSF55608; 1.
DR   TIGRFAMs; TIGR00647; DNA_bind_WhiA; 1.
PE   3: Inferred from homology;
KW   Cell cycle; Cell division; DNA-binding; Reference proteome.
FT   CHAIN           1..319
FT                   /note="Probable cell division protein WhiA"
FT                   /id="PRO_0000376609"
FT   DNA_BIND        277..310
FT                   /note="H-T-H motif"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01420"
SQ   SEQUENCE   319 AA;  34921 MW;  487BCB3C3E6D9B85 CRC64;
     MNSLLQALHL LRCDLLSLPI GDAQTRSAEL TALLRFGADL NIIKRRVVIE VKLCGSLLLN
     RVESVLRNIY GITPKLIRST PRNDIGESCF LLRIDDPSLA RKLGLIDTSL APVRGLPNHL
     ALASGSALKG LVRGAILASG VFTESTRKFA MEVYAPSNET ALCLQGSINK LNVIAKIKEV
     RGSYKVVIRD IDNVAPLLRN VGARNSVEKI EQFIKLRHPE NLGPRLPNFD DANLRRSAIA
     AASSVRRIER ALQILKGDAP QHLLYAGQLR LNNTHASLEE LGKLAEPAMT KDAIAGRIRR
     LLCLADKRAK TLGIPDTFS