WIN1_ARATH
ID WIN1_ARATH Reviewed; 199 AA.
AC Q9XI33; Q8LDZ0;
DT 21-AUG-2007, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1999, sequence version 1.
DT 03-AUG-2022, entry version 141.
DE RecName: Full=Ethylene-responsive transcription factor WIN1;
DE AltName: Full=Protein SHINE 1;
DE AltName: Full=Protein WAX INDUCER 1;
GN Name=WIN1; Synonyms=ERF001, SHN1; OrderedLocusNames=At1g15360;
GN ORFNames=F9L1.31;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA], FUNCTION, AND TISSUE SPECIFICITY.
RC STRAIN=cv. Columbia;
RX PubMed=15070782; DOI=10.1073/pnas.0305574101;
RA Broun P., Poindexter P., Osborne E., Jiang C.-Z., Riechmann J.L.;
RT "WIN1, a transcriptional activator of epidermal wax accumulation in
RT Arabidopsis.";
RL Proc. Natl. Acad. Sci. U.S.A. 101:4706-4711(2004).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130712; DOI=10.1038/35048500;
RA Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL Nature 408:816-820(2000).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=11910074; DOI=10.1126/science.1071006;
RA Seki M., Narusaka M., Kamiya A., Ishida J., Satou M., Sakurai T.,
RA Nakajima M., Enju A., Akiyama K., Oono Y., Muramatsu M., Hayashizaki Y.,
RA Kawai J., Carninci P., Itoh M., Ishii Y., Arakawa T., Shibata K.,
RA Shinagawa A., Shinozaki K.;
RT "Functional annotation of a full-length Arabidopsis cDNA collection.";
RL Science 296:141-145(2002).
RN [5]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [6]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RA Brover V.V., Troukhan M.E., Alexandrov N.A., Lu Y.-P., Flavell R.B.,
RA Feldmann K.A.;
RT "Full-length cDNA from Arabidopsis thaliana.";
RL Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases.
RN [7]
RP FUNCTION, TISSUE SPECIFICITY, AND DEVELOPMENTAL STAGE.
RX PubMed=15319479; DOI=10.1105/tpc.104.022897;
RA Aharoni A., Dixit S., Jetter R., Thoenes E., van Arkel G., Pereira A.;
RT "The SHINE clade of AP2 domain transcription factors activates wax
RT biosynthesis, alters cuticle properties, and confers drought tolerance when
RT overexpressed in Arabidopsis.";
RL Plant Cell 16:2463-2480(2004).
RN [8]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=16407444; DOI=10.1104/pp.105.073783;
RA Nakano T., Suzuki K., Fujimura T., Shinshi H.;
RT "Genome-wide analysis of the ERF gene family in Arabidopsis and rice.";
RL Plant Physiol. 140:411-432(2006).
CC -!- FUNCTION: Promotes cuticle formation by inducing the expression of
CC enzymes involved in wax biosynthesis (PubMed:15070782,
CC PubMed:15319479). Confers drought resistance (PubMed:15319479). Acts as
CC a transcriptional activator. Binds to the GCC-box pathogenesis-related
CC promoter element. May be involved in the regulation of gene expression
CC by stress factors and by components of stress signal transduction
CC pathways (By similarity). {ECO:0000250, ECO:0000269|PubMed:15070782,
CC ECO:0000269|PubMed:15319479}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
CC -!- TISSUE SPECIFICITY: Expressed in aerial organs, mostly in flowers, and
CC in roots. Also observed at the branch points of pedicels of most young
CC flowers, and in a patchy pattern in roots of mature plants and very
CC young leaves in the rosette, including support cells of their
CC trichomes. {ECO:0000269|PubMed:15070782, ECO:0000269|PubMed:15319479}.
CC -!- DEVELOPMENTAL STAGE: Detected in sepals of very young closed buds.
CC Later, expressed in sepals and petals veins and epidermis, as well as
CC in developing gynoecium but not in stamens. At anthesis, confined to
CC the gynoecium, commenced in the anther, and slightly expressed in the
CC anther filament. When petals and sepals withered, strong expression at
CC the bottom of the silique, in the abscission zone, and in the pedicel
CC region below it. At silique maturity, detected in the same region but
CC only at the nectaries. {ECO:0000269|PubMed:15319479}.
CC -!- SIMILARITY: Belongs to the AP2/ERF transcription factor family. ERF
CC subfamily. {ECO:0000305}.
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DR EMBL; AY378101; AAR20494.1; -; mRNA.
DR EMBL; AC007591; AAD39664.1; -; Genomic_DNA.
DR EMBL; CP002684; AEE29310.1; -; Genomic_DNA.
DR EMBL; CP002684; ANM60437.1; -; Genomic_DNA.
DR EMBL; AK117941; BAC42579.1; -; mRNA.
DR EMBL; BT005220; AAO63284.1; -; mRNA.
DR EMBL; AY085720; AAM62938.1; -; mRNA.
DR PIR; B86288; B86288.
DR RefSeq; NP_001322723.1; NM_001332163.1.
DR RefSeq; NP_172988.1; NM_101405.4.
DR AlphaFoldDB; Q9XI33; -.
DR SMR; Q9XI33; -.
DR BioGRID; 23345; 1.
DR STRING; 3702.AT1G15360.1; -.
DR PaxDb; Q9XI33; -.
DR PRIDE; Q9XI33; -.
DR EnsemblPlants; AT1G15360.1; AT1G15360.1; AT1G15360.
DR EnsemblPlants; AT1G15360.2; AT1G15360.2; AT1G15360.
DR GeneID; 838105; -.
DR Gramene; AT1G15360.1; AT1G15360.1; AT1G15360.
DR Gramene; AT1G15360.2; AT1G15360.2; AT1G15360.
DR KEGG; ath:AT1G15360; -.
DR Araport; AT1G15360; -.
DR TAIR; locus:2037698; AT1G15360.
DR eggNOG; ENOG502RXIC; Eukaryota.
DR HOGENOM; CLU_042594_3_0_1; -.
DR OMA; ARMMCGP; -.
DR OrthoDB; 1336707at2759; -.
DR PhylomeDB; Q9XI33; -.
DR PRO; PR:Q9XI33; -.
DR Proteomes; UP000006548; Chromosome 1.
DR ExpressionAtlas; Q9XI33; baseline and differential.
DR Genevisible; Q9XI33; AT.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IDA:TAIR.
DR GO; GO:0043565; F:sequence-specific DNA binding; IPI:TAIR.
DR GO; GO:0010143; P:cutin biosynthetic process; IMP:TAIR.
DR GO; GO:0009873; P:ethylene-activated signaling pathway; TAS:TAIR.
DR GO; GO:0009414; P:response to water deprivation; IMP:TAIR.
DR GO; GO:0010166; P:wax metabolic process; IMP:TAIR.
DR CDD; cd00018; AP2; 1.
DR Gene3D; 3.30.730.10; -; 1.
DR InterPro; IPR001471; AP2/ERF_dom.
DR InterPro; IPR036955; AP2/ERF_dom_sf.
DR InterPro; IPR016177; DNA-bd_dom_sf.
DR Pfam; PF00847; AP2; 1.
DR PRINTS; PR00367; ETHRSPELEMNT.
DR SMART; SM00380; AP2; 1.
DR SUPFAM; SSF54171; SSF54171; 1.
DR PROSITE; PS51032; AP2_ERF; 1.
PE 2: Evidence at transcript level;
KW Activator; DNA-binding; Ethylene signaling pathway; Nucleus;
KW Reference proteome; Transcription; Transcription regulation.
FT CHAIN 1..199
FT /note="Ethylene-responsive transcription factor WIN1"
FT /id="PRO_0000297945"
FT DNA_BIND 6..63
FT /note="AP2/ERF"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00366"
FT REGION 60..92
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT CONFLICT 47
FT /note="D -> H (in Ref. 6; AAM62938)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 199 AA; 21696 MW; A780747798DE922B CRC64;
MVQTKKFRGV RQRHWGSWVA EIRHPLLKRR IWLGTFETAE EAARAYDEAA VLMSGRNAKT
NFPLNNNNTG ETSEGKTDIS ASSTMSSSTS SSSLSSILSA KLRKCCKSPS PSLTCLRLDT
ASSHIGVWQK RAGSKSDSSW VMTVELGPAS SSQETTSKAS QDAILAPTTE VEIGGSREEV
LDEEEKVALQ MIEELLNTN
