WK72A_SOLLC
ID WK72A_SOLLC Reviewed; 526 AA.
AC A0A3Q7GFB5; D8VNC5;
DT 03-JUL-2019, integrated into UniProtKB/Swiss-Prot.
DT 10-APR-2019, sequence version 1.
DT 25-MAY-2022, entry version 14.
DE RecName: Full=WRKY transcription factor 72A {ECO:0000305};
DE Short=SlWRKY72a {ECO:0000303|PubMed:20409007};
DE AltName: Full=SlWRKY73 {ECO:0000303|PubMed:24884371};
DE AltName: Full=WRKY DNA-binding protein 72A {ECO:0000305};
GN Name=WRKY72A {ECO:0000303|PubMed:20409007};
GN Synonyms=WRKY73 {ECO:0000303|PubMed:24884371};
GN OrderedLocusNames=Solyc03g113120 {ECO:0000305};
OS Solanum lycopersicum (Tomato) (Lycopersicon esculentum).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; lamiids; Solanales; Solanaceae; Solanoideae; Solaneae; Solanum;
OC Solanum subgen. Lycopersicon.
OX NCBI_TaxID=4081;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA], FUNCTION, AND INDUCTION.
RX PubMed=20409007; DOI=10.1111/j.1365-313x.2010.04232.x;
RA Bhattarai K.K., Atamian H.S., Kaloshian I., Eulgem T.;
RT "WRKY72-type transcription factors contribute to basal immunity in tomato
RT and Arabidopsis as well as gene-for-gene resistance mediated by the tomato
RT R gene Mi-1.";
RL Plant J. 63:229-240(2010).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Heinz 1706;
RX PubMed=22660326; DOI=10.1038/nature11119;
RG Tomato Genome Consortium;
RT "The tomato genome sequence provides insights into fleshy fruit
RT evolution.";
RL Nature 485:635-641(2012).
RN [3]
RP FUNCTION, AND TISSUE SPECIFICITY.
RX PubMed=24884371; DOI=10.1186/1471-2164-15-402;
RA Spyropoulou E.A., Haring M.A., Schuurink R.C.;
RT "RNA sequencing on Solanum lycopersicum trichomes identifies transcription
RT factors that activate terpene synthase promoters.";
RL BMC Genomics 15:402-402(2014).
CC -!- FUNCTION: Transcription activator involved in the transcriptional
CC regulation of terpene biosynthesis in glandular trichomes
CC (PubMed:24884371). Binds to the promoter of the linalool synthase TPS5
CC and promotes TPS5 gene transactivation (PubMed:24884371). In
CC association with WRKY72B, contributes to basal defense against root-
CC knot nematodes (RKNs) and potato aphids, as well as Mi-1-mediated gene-
CC for-gene resistance to these pests (PubMed:20409007). Both WRKY72A and
CC WRKY72B are not required for gene-for-gene resistance mediated by Pto,
CC another tomato R gene (PubMed:20409007). {ECO:0000269|PubMed:20409007,
CC ECO:0000269|PubMed:24884371}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00223}.
CC -!- TISSUE SPECIFICITY: Expressed in roots, trichomes and fruits.
CC {ECO:0000269|PubMed:24884371}.
CC -!- INDUCTION: Induced by infection with the root-knot nematode (RKN)
CC Meloidogyne incognita and potato aphids. {ECO:0000269|PubMed:20409007}.
CC -!- MISCELLANEOUS: Plants silencing WRKY72A show a reduction of the R gene
CC Mi-1-mediated resistance as well as basal defense against root-knot
CC nematodes (RKNs) and potato aphids. {ECO:0000269|PubMed:20409007}.
CC -!- SIMILARITY: Belongs to the WRKY group II-b family. {ECO:0000305}.
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DR EMBL; GU017421; ADK23849.1; -; mRNA.
DR EMBL; CM001066; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; NP_001234802.2; NM_001247873.2.
DR AlphaFoldDB; A0A3Q7GFB5; -.
DR SMR; A0A3Q7GFB5; -.
DR STRING; 4081.Solyc03g113120.2.1; -.
DR EnsemblPlants; Solyc03g113120.3.1; Solyc03g113120.3.1; Solyc03g113120.3.
DR GeneID; 100529138; -.
DR Gramene; Solyc03g113120.3.1; Solyc03g113120.3.1; Solyc03g113120.3.
DR KEGG; sly:100529138; -.
DR OMA; YRCTIAA; -.
DR OrthoDB; 627539at2759; -.
DR Proteomes; UP000004994; Chromosome 3.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR GO; GO:0006952; P:defense response; IEA:UniProtKB-KW.
DR Gene3D; 2.20.25.80; -; 1.
DR InterPro; IPR003657; WRKY_dom.
DR InterPro; IPR036576; WRKY_dom_sf.
DR InterPro; IPR044810; WRKY_plant.
DR PANTHER; PTHR31429; PTHR31429; 1.
DR Pfam; PF03106; WRKY; 1.
DR SMART; SM00774; WRKY; 1.
DR SUPFAM; SSF118290; SSF118290; 1.
DR PROSITE; PS50811; WRKY; 1.
PE 2: Evidence at transcript level;
KW Activator; Coiled coil; DNA-binding; Nucleus; Plant defense;
KW Reference proteome; Transcription; Transcription regulation.
FT CHAIN 1..526
FT /note="WRKY transcription factor 72A"
FT /id="PRO_0000447556"
FT DNA_BIND 232..298
FT /note="WRKY"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00223"
FT REGION 40..76
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 170..200
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 62..106
FT /evidence="ECO:0000255"
FT COMPBIAS 170..184
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 185..200
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT CONFLICT 1..2
FT /note="Missing (in Ref. 1; ADK23849)"
FT /evidence="ECO:0000305"
FT CONFLICT 208
FT /note="I -> M (in Ref. 1; ADK23849)"
FT /evidence="ECO:0000305"
FT CONFLICT 325
FT /note="G -> D (in Ref. 1; ADK23849)"
FT /evidence="ECO:0000305"
FT CONFLICT 401
FT /note="Y -> YNNN (in Ref. 1; ADK23849)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 526 AA; 58437 MW; 7AA1B24386E429CC CRC64;
MHMETVFRKS THGGVVKQDI KIKASEEGFV EDINDLKVEK ERKSIHNEDD NSKSSQQKDL
TGDKKDDQLE SAKADMEEVM EENQRLKKHL DKIMKDYRNL QMQFHEVAQR DAEKTNTDVK
HDEAELVSLS LGRTSSDTKK ELSKLILSKK ENDEKEEDNL TLALDCKFQS STKSSPSNLS
PENSLGEVKD DEKGTDQTWP PHKVLKTIRN EEDDVTQQNP TKRAKVSVRV RCDTPTMNDG
CQWRKYGQKI AKGNPCPRAY YRCTVAPNCP VRKQVQRCIQ DMSILITTYE GTHNHPLPHS
ATSMAFTTSA AASMLLSGSS SSGSGPTSST ASATTSALNY CFSDNSKPNP FYNLPHSSIS
SSSHSQYPTI TLDLTSNSST SSFPGQNYRT IANSNNYPPR YNNNNSSTNI LNFSSFESNH
LLPMSWSNRN NQDTHSQSYL QNNIKSAAST QTLLPQDTIA AATKAITSDP KFQSALAVAL
TSIIGSRSGN HHIDEKSGQN MKVTEPFPVL CSFPSTSPGD HKDYTL
