ID   WOR1_GIBM7              Reviewed;         328 AA.
AC   W7MPI5;
DT   07-JAN-2015, integrated into UniProtKB/Swiss-Prot.
DT   16-APR-2014, sequence version 1.
DT   25-MAY-2022, entry version 25.
DE   RecName: Full=Global transcription regulator sge1 {ECO:0000305};
GN   Name=sge1 {ECO:0000303|PubMed:24742071};
GN   ORFNames=FVEG_09150 {ECO:0000312|EMBL:EWG49689.1};
OS   Gibberella moniliformis (strain M3125 / FGSC 7600) (Maize ear and stalk rot
OS   fungus) (Fusarium verticillioides).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC   Hypocreomycetidae; Hypocreales; Nectriaceae; Fusarium;
OC   Fusarium fujikuroi species complex.
OX   NCBI_TaxID=334819;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=M3125 / FGSC 7600;
RX   PubMed=20237561; DOI=10.1038/nature08850;
RA   Ma L.-J., van der Does H.C., Borkovich K.A., Coleman J.J., Daboussi M.-J.,
RA   Di Pietro A., Dufresne M., Freitag M., Grabherr M., Henrissat B.,
RA   Houterman P.M., Kang S., Shim W.-B., Woloshuk C., Xie X., Xu J.-R.,
RA   Antoniw J., Baker S.E., Bluhm B.H., Breakspear A., Brown D.W.,
RA   Butchko R.A.E., Chapman S., Coulson R., Coutinho P.M., Danchin E.G.J.,
RA   Diener A., Gale L.R., Gardiner D.M., Goff S., Hammond-Kosack K.E.,
RA   Hilburn K., Hua-Van A., Jonkers W., Kazan K., Kodira C.D., Koehrsen M.,
RA   Kumar L., Lee Y.-H., Li L., Manners J.M., Miranda-Saavedra D.,
RA   Mukherjee M., Park G., Park J., Park S.-Y., Proctor R.H., Regev A.,
RA   Ruiz-Roldan M.C., Sain D., Sakthikumar S., Sykes S., Schwartz D.C.,
RA   Turgeon B.G., Wapinski I., Yoder O., Young S., Zeng Q., Zhou S.,
RA   Galagan J., Cuomo C.A., Kistler H.C., Rep M.;
RT   "Comparative genomics reveals mobile pathogenicity chromosomes in
RT   Fusarium.";
RL   Nature 464:367-373(2010).
RN   [2]
RP   FUNCTION.
RX   PubMed=24742071; DOI=10.1094/mpmi-09-13-0281-r;
RA   Brown D.W., Busman M., Proctor R.H.;
RT   "Fusarium verticillioides SGE1 is required for full virulence and regulates
RT   expression of protein effector and secondary metabolite biosynthetic
RT   genes.";
RL   Mol. Plant Microbe Interact. 27:809-823(2014).
CC   -!- FUNCTION: Global transcriptional regulator of transcription that
CC       impacts, but is not absolutely required for secondary metabolism and
CC       pathogenicity on maize. Regulates synthesis of multiple secondary
CC       metabolites, including fumonisins and fusarins.
CC       {ECO:0000269|PubMed:24742071}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250|UniProtKB:J9N5P9}.
CC   -!- SIMILARITY: Belongs to the MIT1/WOR1 family. {ECO:0000305}.
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DR   EMBL; DS022253; EWG49689.1; -; Genomic_DNA.
DR   RefSeq; XP_018755880.1; XM_018898080.1.
DR   AlphaFoldDB; W7MPI5; -.
DR   SMR; W7MPI5; -.
DR   STRING; 117187.FVEG_09150T0; -.
DR   EnsemblFungi; FVEG_09150T0; FVEG_09150T0; FVEG_09150.
DR   GeneID; 30066829; -.
DR   KEGG; fvr:FVEG_09150; -.
DR   VEuPathDB; FungiDB:FVEG_09150; -.
DR   eggNOG; KOG4476; Eukaryota.
DR   HOGENOM; CLU_028895_3_0_1; -.
DR   OMA; HQPQVHQ; -.
DR   OrthoDB; 1503680at2759; -.
DR   PHI-base; PHI:4225; -.
DR   Proteomes; UP000009096; Chromosome 5.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   InterPro; IPR018608; Gti1/Pac2.
DR   PANTHER; PTHR28027; PTHR28027; 1.
DR   Pfam; PF09729; Gti1_Pac2; 1.
PE   3: Inferred from homology;
KW   Nucleus; Reference proteome; Transcription; Transcription regulation;
KW   Virulence.
FT   CHAIN           1..328
FT                   /note="Global transcription regulator sge1"
FT                   /id="PRO_0000431523"
FT   REGION          94..120
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          251..293
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        105..120
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   328 AA;  36893 MW;  D9DF0759BD0A5FA3 CRC64;
     MSGTTQLRPT YHGYVRDTTD ALIIFEACLA GQLLHVPRRP HDRERQNVIK SGSIFVYEEH
     ASGIKRWTDS ITWSPSRIMG NYLVYRQLEK PFAPGEKKRA KGKGGKSTTQ SGGISKPRQR
     NALPFQQGLE QGNEYPSVPS DEDRQLVGSL VDSYDFKEQG LVKKTISITY NGVPHHLISY
     YTVEDVKAGL LTSPADDQGL RGVVPRAELT NGQNFRAPIE ESIGGAYMPG MRHSAGFPHP
     SAYPTLLHQP QMHQPQVHQP LAHQPQVHQP LAHQPQVHQP LAHQPQVHQQ YVHQPQAHQP
     YMHQPQVHLN GYQPSYGDGQ WWKYLGGT