ID   WOX12_ORYSJ             Reviewed;         515 AA.
AC   A3B6V0; A0AAT4; Q6AUF7;
DT   23-OCT-2007, integrated into UniProtKB/Swiss-Prot.
DT   23-OCT-2007, sequence version 2.
DT   03-AUG-2022, entry version 86.
DE   RecName: Full=WUSCHEL-related homeobox 12;
DE   AltName: Full=OsWOX12;
DE   AltName: Full=Protein WOX9C;
GN   Name=WOX12; OrderedLocusNames=Os05g0564500, LOC_Os05g48990;
GN   ORFNames=OsJ_018772, OSJNBb0053D02.14;
OS   Oryza sativa subsp. japonica (Rice).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC   Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX   NCBI_TaxID=39947;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Nipponbare;
RX   PubMed=16261349; DOI=10.1007/s00438-005-0039-y;
RA   Cheng C.-H., Chung M.C., Liu S.-M., Chen S.-K., Kao F.Y., Lin S.-J.,
RA   Hsiao S.-H., Tseng I.C., Hsing Y.-I.C., Wu H.-P., Chen C.-S., Shaw J.-F.,
RA   Wu J., Matsumoto T., Sasaki T., Chen H.-C., Chow T.-Y.;
RT   "A fine physical map of the rice chromosome 5.";
RL   Mol. Genet. Genomics 274:337-345(2005).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Nipponbare;
RX   PubMed=16100779; DOI=10.1038/nature03895;
RG   International rice genome sequencing project (IRGSP);
RT   "The map-based sequence of the rice genome.";
RL   Nature 436:793-800(2005).
RN   [3]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Nipponbare;
RX   PubMed=24280374; DOI=10.1186/1939-8433-6-4;
RA   Kawahara Y., de la Bastide M., Hamilton J.P., Kanamori H., McCombie W.R.,
RA   Ouyang S., Schwartz D.C., Tanaka T., Wu J., Zhou S., Childs K.L.,
RA   Davidson R.M., Lin H., Quesada-Ocampo L., Vaillancourt B., Sakai H.,
RA   Lee S.S., Kim J., Numa H., Itoh T., Buell C.R., Matsumoto T.;
RT   "Improvement of the Oryza sativa Nipponbare reference genome using next
RT   generation sequence and optical map data.";
RL   Rice 6:4-4(2013).
RN   [4]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Nipponbare;
RX   PubMed=15685292; DOI=10.1371/journal.pbio.0030038;
RA   Yu J., Wang J., Lin W., Li S., Li H., Zhou J., Ni P., Dong W., Hu S.,
RA   Zeng C., Zhang J., Zhang Y., Li R., Xu Z., Li S., Li X., Zheng H., Cong L.,
RA   Lin L., Yin J., Geng J., Li G., Shi J., Liu J., Lv H., Li J., Wang J.,
RA   Deng Y., Ran L., Shi X., Wang X., Wu Q., Li C., Ren X., Wang J., Wang X.,
RA   Li D., Liu D., Zhang X., Ji Z., Zhao W., Sun Y., Zhang Z., Bao J., Han Y.,
RA   Dong L., Ji J., Chen P., Wu S., Liu J., Xiao Y., Bu D., Tan J., Yang L.,
RA   Ye C., Zhang J., Xu J., Zhou Y., Yu Y., Zhang B., Zhuang S., Wei H.,
RA   Liu B., Lei M., Yu H., Li Y., Xu H., Wei S., He X., Fang L., Zhang Z.,
RA   Zhang Y., Huang X., Su Z., Tong W., Li J., Tong Z., Li S., Ye J., Wang L.,
RA   Fang L., Lei T., Chen C.-S., Chen H.-C., Xu Z., Li H., Huang H., Zhang F.,
RA   Xu H., Li N., Zhao C., Li S., Dong L., Huang Y., Li L., Xi Y., Qi Q.,
RA   Li W., Zhang B., Hu W., Zhang Y., Tian X., Jiao Y., Liang X., Jin J.,
RA   Gao L., Zheng W., Hao B., Liu S.-M., Wang W., Yuan L., Cao M.,
RA   McDermott J., Samudrala R., Wang J., Wong G.K.-S., Yang H.;
RT   "The genomes of Oryza sativa: a history of duplications.";
RL   PLoS Biol. 3:266-281(2005).
RN   [5]
RP   NUCLEOTIDE SEQUENCE [MRNA] OF 68-132.
RX   PubMed=16987950; DOI=10.1093/molbev/msl125;
RA   Nardmann J., Werr W.;
RT   "The shoot stem cell niche in angiosperms: expression patterns of WUS
RT   orthologues in rice and maize imply major modifications in the course of
RT   mono- and dicot evolution.";
RL   Mol. Biol. Evol. 23:2492-2504(2006).
CC   -!- FUNCTION: Transcription factor which may be involved in developmental
CC       processes. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00108}.
CC   -!- SIMILARITY: Belongs to the WUS homeobox family. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAT77402.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR   EMBL; AC124143; AAT77402.1; ALT_SEQ; Genomic_DNA.
DR   EMBL; AP014961; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; CM000142; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AM234753; CAJ84145.1; -; mRNA.
DR   AlphaFoldDB; A3B6V0; -.
DR   SMR; A3B6V0; -.
DR   STRING; 4530.OS05T0564500-00; -.
DR   PaxDb; A3B6V0; -.
DR   PRIDE; A3B6V0; -.
DR   eggNOG; ENOG502QVSY; Eukaryota.
DR   HOGENOM; CLU_191894_0_0_1; -.
DR   InParanoid; A3B6V0; -.
DR   Proteomes; UP000000763; Chromosome 5.
DR   Proteomes; UP000007752; Chromosome 5.
DR   Proteomes; UP000059680; Chromosome 5.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0050793; P:regulation of developmental process; IEA:InterPro.
DR   CDD; cd00086; homeodomain; 1.
DR   InterPro; IPR009057; Homeobox-like_sf.
DR   InterPro; IPR001356; Homeobox_dom.
DR   InterPro; IPR044557; WOX8/9-like.
DR   PANTHER; PTHR47288; PTHR47288; 1.
DR   Pfam; PF00046; Homeodomain; 1.
DR   SMART; SM00389; HOX; 1.
DR   SUPFAM; SSF46689; SSF46689; 1.
DR   PROSITE; PS50071; HOMEOBOX_2; 1.
PE   2: Evidence at transcript level;
KW   Developmental protein; DNA-binding; Homeobox; Nucleus; Reference proteome;
KW   Transcription; Transcription regulation.
FT   CHAIN           1..515
FT                   /note="WUSCHEL-related homeobox 12"
FT                   /id="PRO_0000308649"
FT   DNA_BIND        68..132
FT                   /note="Homeobox; WUS-type"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00108"
FT   REGION          23..76
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          130..156
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          176..195
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        23..61
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        130..145
FT                   /note="Basic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   515 AA;  54610 MW;  9BCF56F0994359A6 CRC64;
     MASPNRHWPS MFRSNLACNI QQQQQPDMNG NGSSSSSFLL SPPTAATTGN GKPSLLSSGC
     EEGTRNPEPK PRWNPRPEQI RILEGIFNSG MVNPPRDEIR RIRLQLQEYG QVGDANVFYW
     FQNRKSRTKN KLRAAGHHHH HGRAAALPRA SAPPSTNIVL PSAAAAAPLT PPRRHLLAAT
     SSSSSSSDRS SGSSKSVKPA AAALLTSAAI DLFSPAPAPT TQLPACQLYY HSHPTPLARD
     DQLITSPESS SLLLQWPASQ YMPATELGGV LGSSSHTQTP AAITTHPSTI SPSVLLGLCN
     EALGQHQQET MDDMMITCSN PSKVFDHHSM DDMSCTDAVS AVNRDDEKAR LGLLHYGIGV
     TAAANPAPHH HHHHHHLASP VHDAVSAADA STAAMILPFT TTAAATPSNV VATSSALADQ
     LQGLLDAGLL QGGAAPPPPS ATVVAVSRDD ETMCTKTTSY SFPATMHLNV KMFGEAAVLV
     RYSGEPVLVD DSGVTVEPLQ QGATYYVLVS EEAVH