ID   WOX1_ARATH              Reviewed;         350 AA.
AC   Q6X7K0; Q9LVH2;
DT   15-MAR-2005, integrated into UniProtKB/Swiss-Prot.
DT   15-MAR-2005, sequence version 2.
DT   03-AUG-2022, entry version 119.
DE   RecName: Full=WUSCHEL-related homeobox 1;
DE   AltName: Full=PFS2-like protein;
GN   Name=WOX1; OrderedLocusNames=At3g18010; ORFNames=MEB5.20, MEB5.23;
OS   Arabidopsis thaliana (Mouse-ear cress).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX   NCBI_TaxID=3702;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA], AND DEVELOPMENTAL STAGE.
RC   STRAIN=cv. Landsberg erecta;
RX   PubMed=14711878; DOI=10.1242/dev.00963;
RA   Haecker A., Gross-Hardt R., Geiges B., Sarkar A., Breuninger H.,
RA   Herrmann M., Laux T.;
RT   "Expression dynamics of WOX genes mark cell fate decisions during early
RT   embryonic patterning in Arabidopsis thaliana.";
RL   Development 131:657-668(2004).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=10819329; DOI=10.1093/dnares/7.2.131;
RA   Sato S., Nakamura Y., Kaneko T., Katoh T., Asamizu E., Tabata S.;
RT   "Structural analysis of Arabidopsis thaliana chromosome 3. I. Sequence
RT   features of the regions of 4,504,864 bp covered by sixty P1 and TAC
RT   clones.";
RL   DNA Res. 7:131-135(2000).
RN   [3]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Columbia;
RX   PubMed=27862469; DOI=10.1111/tpj.13415;
RA   Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA   Town C.D.;
RT   "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT   genome.";
RL   Plant J. 89:789-804(2017).
CC   -!- FUNCTION: Transcription factor which may be involved in developmental
CC       processes. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00108}.
CC   -!- DEVELOPMENTAL STAGE: Specifically expressed during initiation of the
CC       shoot apical meristem, when cotyledonary primordia arise at the flanks
CC       of the apical embryo domain phase. Confined to the initiating vascular
CC       primordium of the cotyledons during heart and torpedo stages, but only
CC       weakly expressed during bent cotyledon stage.
CC       {ECO:0000269|PubMed:14711878}.
CC   -!- SIMILARITY: Belongs to the WUS homeobox family. {ECO:0000305}.
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DR   EMBL; AY251394; AAP37133.1; -; mRNA.
DR   EMBL; AB019230; BAB02721.1; -; Genomic_DNA.
DR   EMBL; CP002686; AEE76034.1; -; Genomic_DNA.
DR   RefSeq; NP_188428.3; NM_112682.4.
DR   AlphaFoldDB; Q6X7K0; -.
DR   SMR; Q6X7K0; -.
DR   BioGRID; 6658; 5.
DR   IntAct; Q6X7K0; 4.
DR   STRING; 3702.AT3G18010.1; -.
DR   PaxDb; Q6X7K0; -.
DR   PRIDE; Q6X7K0; -.
DR   EnsemblPlants; AT3G18010.1; AT3G18010.1; AT3G18010.
DR   GeneID; 821325; -.
DR   Gramene; AT3G18010.1; AT3G18010.1; AT3G18010.
DR   KEGG; ath:AT3G18010; -.
DR   Araport; AT3G18010; -.
DR   TAIR; locus:2088550; AT3G18010.
DR   eggNOG; ENOG502QVAV; Eukaryota.
DR   HOGENOM; CLU_777096_0_0_1; -.
DR   InParanoid; Q6X7K0; -.
DR   OMA; SAIHCFY; -.
DR   OrthoDB; 773356at2759; -.
DR   PhylomeDB; Q6X7K0; -.
DR   PRO; PR:Q6X7K0; -.
DR   Proteomes; UP000006548; Chromosome 3.
DR   ExpressionAtlas; Q6X7K0; baseline and differential.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; ISS:TAIR.
DR   GO; GO:0099402; P:plant organ development; IGI:TAIR.
DR   CDD; cd00086; homeodomain; 1.
DR   InterPro; IPR009057; Homeobox-like_sf.
DR   InterPro; IPR001356; Homeobox_dom.
DR   InterPro; IPR044555; WUSCHEL-like.
DR   PANTHER; PTHR45940; PTHR45940; 1.
DR   Pfam; PF00046; Homeodomain; 1.
DR   SMART; SM00389; HOX; 1.
DR   SUPFAM; SSF46689; SSF46689; 1.
DR   PROSITE; PS50071; HOMEOBOX_2; 1.
PE   2: Evidence at transcript level;
KW   Developmental protein; DNA-binding; Homeobox; Nucleus; Reference proteome;
KW   Transcription; Transcription regulation.
FT   CHAIN           1..350
FT                   /note="WUSCHEL-related homeobox 1"
FT                   /id="PRO_0000049365"
FT   DNA_BIND        72..136
FT                   /note="Homeobox; WUS-type"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00108"
FT   REGION          283..308
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   CONFLICT        152
FT                   /note="A -> T (in Ref. 1; AAP37133)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        173
FT                   /note="V -> A (in Ref. 1; AAP37133)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        248
FT                   /note="Missing (in Ref. 1; AAP37133)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   350 AA;  40143 MW;  14E3593A9ABFC110 CRC64;
     MWTMGYNEGG ADSFNGGRKL RPLIPRLTSC PTAAVNTNSD HRFNMAVVTM TAEQNKRELM
     MLNSEPQHPP VMVSSRWNPT PDQLRVLEEL YRQGTRTPSA DHIQQITAQL RRYGKIEGKN
     VFYWFQNHKA RERQKRRRQM ETGHEETVLS TASLVSNHGF DKKDPPGYKV EQVKNWICSV
     GCDTQPEKPS RDYHLEEPAN IRVEHNARCG GDERRSFLGI NTTWQMMQLP PSFYSSSHHH
     HQRNLILNSP TVSSNMSNSN NAVSASKDTV TVSPVFLRTR EATNTETCHR NGDDNKDQEQ
     HEDCSNGELD HQEQTLELFP LRKEGFCSDG EKDKNISGIH CFYEFLPLKN