WOX1_ORYSJ
ID WOX1_ORYSJ Reviewed; 289 AA.
AC Q7XM13; A0A0N7KJV6; A0AAS7; A3AYC1; Q33DK0;
DT 23-OCT-2007, integrated into UniProtKB/Swiss-Prot.
DT 13-FEB-2019, sequence version 3.
DT 25-MAY-2022, entry version 108.
DE RecName: Full=WUSCHEL-related homeobox 1 {ECO:0000305};
DE Short=OsWOX1 {ECO:0000303|PubMed:17351053};
DE AltName: Full=Protein MONOCULM 3 {ECO:0000303|PubMed:25697101};
DE AltName: Full=Protein STERILE AND REDUCED TILLERING 1 {ECO:0000303|PubMed:27194802};
DE AltName: Full=Protein TILLERS ABSENT 1 {ECO:0000303|PubMed:25841039};
DE AltName: Full=Protein WUS {ECO:0000303|PubMed:16987950};
DE Short=OsWUS {ECO:0000303|PubMed:16284419};
GN Name=WOX1 {ECO:0000303|PubMed:17351053};
GN Synonyms=MOC3 {ECO:0000303|PubMed:25697101},
GN SRT1 {ECO:0000303|PubMed:27194802}, TAB1 {ECO:0000303|PubMed:25841039},
GN WUS {ECO:0000303|PubMed:16987950};
GN OrderedLocusNames=Os04g0663600 {ECO:0000312|EMBL:BAS91481.1},
GN LOC_Os04g56780 {ECO:0000305};
GN ORFNames=OSJNBa0084K01.1 {ECO:0000312|EMBL:CAE04846.2};
OS Oryza sativa subsp. japonica (Rice).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX NCBI_TaxID=39947;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA], AND TISSUE SPECIFICITY.
RC STRAIN=cv. Taichung 65; TISSUE=Flower;
RX PubMed=16284419; DOI=10.1266/ggs.80.261;
RA Nagasaki H., Matsuoka M., Sato Y.;
RT "Members of TALE and WUS subfamilies of homeodomain proteins with
RT potentially important functions in development form dimers within each
RT subfamily in rice.";
RL Genes Genet. Syst. 80:261-267(2005).
RN [2]
RP NUCLEOTIDE SEQUENCE [MRNA].
RX PubMed=16987950; DOI=10.1093/molbev/msl125;
RA Nardmann J., Werr W.;
RT "The shoot stem cell niche in angiosperms: expression patterns of WUS
RT orthologues in rice and maize imply major modifications in the course of
RT mono- and dicot evolution.";
RL Mol. Biol. Evol. 23:2492-2504(2006).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=12447439; DOI=10.1038/nature01183;
RA Feng Q., Zhang Y., Hao P., Wang S., Fu G., Huang Y., Li Y., Zhu J., Liu Y.,
RA Hu X., Jia P., Zhang Y., Zhao Q., Ying K., Yu S., Tang Y., Weng Q.,
RA Zhang L., Lu Y., Mu J., Lu Y., Zhang L.S., Yu Z., Fan D., Liu X., Lu T.,
RA Li C., Wu Y., Sun T., Lei H., Li T., Hu H., Guan J., Wu M., Zhang R.,
RA Zhou B., Chen Z., Chen L., Jin Z., Wang R., Yin H., Cai Z., Ren S., Lv G.,
RA Gu W., Zhu G., Tu Y., Jia J., Zhang Y., Chen J., Kang H., Chen X., Shao C.,
RA Sun Y., Hu Q., Zhang X., Zhang W., Wang L., Ding C., Sheng H., Gu J.,
RA Chen S., Ni L., Zhu F., Chen W., Lan L., Lai Y., Cheng Z., Gu M., Jiang J.,
RA Li J., Hong G., Xue Y., Han B.;
RT "Sequence and analysis of rice chromosome 4.";
RL Nature 420:316-320(2002).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=16100779; DOI=10.1038/nature03895;
RG International rice genome sequencing project (IRGSP);
RT "The map-based sequence of the rice genome.";
RL Nature 436:793-800(2005).
RN [5]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=24280374; DOI=10.1186/1939-8433-6-4;
RA Kawahara Y., de la Bastide M., Hamilton J.P., Kanamori H., McCombie W.R.,
RA Ouyang S., Schwartz D.C., Tanaka T., Wu J., Zhou S., Childs K.L.,
RA Davidson R.M., Lin H., Quesada-Ocampo L., Vaillancourt B., Sakai H.,
RA Lee S.S., Kim J., Numa H., Itoh T., Buell C.R., Matsumoto T.;
RT "Improvement of the Oryza sativa Nipponbare reference genome using next
RT generation sequence and optical map data.";
RL Rice 6:4-4(2013).
RN [6]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=17351053; DOI=10.1104/pp.107.095737;
RA Dai M., Hu Y., Zhao Y., Liu H., Zhou D.-X.;
RT "A WUSCHEL-LIKE HOMEOBOX gene represses a YABBY gene expression required
RT for rice leaf development.";
RL Plant Physiol. 144:380-390(2007).
RN [7]
RP FUNCTION, INTERACTION WITH TPR1; TPR2 AND TPR3, SUBCELLULAR LOCATION,
RP INDUCTION BY CYTOKININ, AND DISRUPTION PHENOTYPE.
RX PubMed=25697101; DOI=10.1016/j.jgg.2014.12.005;
RA Lu Z., Shao G., Xiong J., Jiao Y., Wang J., Liu G., Meng X., Liang Y.,
RA Xiong G., Wang Y., Li J.;
RT "MONOCULM 3, an ortholog of WUSCHEL in rice, is required for tiller bud
RT formation.";
RL J. Genet. Genomics 42:71-78(2015).
RN [8]
RP FUNCTION, AND DISRUPTION PHENOTYPE.
RX PubMed=25841039; DOI=10.1105/tpc.15.00074;
RA Tanaka W., Ohmori Y., Ushijima T., Matsusaka H., Matsushita T.,
RA Kumamaru T., Kawano S., Hirano H.Y.;
RT "Axillary meristem formation in rice requires the WUSCHEL ortholog TILLERS
RT ABSENT1.";
RL Plant Cell 27:1173-1184(2015).
RN [9]
RP FUNCTION, AND MUTAGENESIS OF 79-LYS--PHE-85.
RX PubMed=27194802; DOI=10.1534/g3.116.028837;
RA Mjomba F.M., Zheng Y., Liu H., Tang W., Hong Z., Wang F., Wu W.;
RT "Homeobox is pivotal for OsWUS controlling tiller development and female
RT fertility in rice.";
RL G3 (Bethesda) 6:2013-2021(2016).
CC -!- FUNCTION: Transcription repressor required for the formation and
CC development of tiller buds and panicles (PubMed:25697101). Required for
CC tiller formation and female sterility (PubMed:27194802). Required for
CC the early developmental stages of axillary meristem formation
CC (PubMed:25841039). Plays a role in maintaining the axillary premeristem
CC zone and in promoting the formation of the axillary meristem by
CC promoting OSH1 expression (PubMed:25841039). Does not seem to be
CC involved in maintenance of the shoot apical meristem (SAM)
CC (PubMed:25841039). {ECO:0000269|PubMed:25697101,
CC ECO:0000269|PubMed:25841039, ECO:0000269|PubMed:27194802}.
CC -!- SUBUNIT: Interacts with TPR1, TPR2 and TPR3.
CC {ECO:0000269|PubMed:25697101}.
CC -!- INTERACTION:
CC Q7XM13; Q33DK1: WOX3; NbExp=3; IntAct=EBI-1100547, EBI-1100563;
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00108,
CC ECO:0000269|PubMed:25697101}.
CC -!- TISSUE SPECIFICITY: Expressed in young leaf primordia. Expressed in
CC branch an floral meristems. Transiently expressed in the shoot apex.
CC {ECO:0000269|PubMed:16284419}.
CC -!- INDUCTION: Induced by the cytokinin 6-benzylaminopurine.
CC {ECO:0000269|PubMed:17351053}.
CC -!- DISRUPTION PHENOTYPE: Disrupted formation of tiller buds, and female
CC sterility (PubMed:25697101). Defects in axillary bud formation, and
CC partial defects in branching of the panicle (PubMed:25841039).
CC {ECO:0000269|PubMed:25697101, ECO:0000269|PubMed:25841039}.
CC -!- SIMILARITY: Belongs to the WUS homeobox family. {ECO:0000305}.
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DR EMBL; AB218894; BAE48303.1; -; mRNA.
DR EMBL; AM234746; CAJ84138.1; -; mRNA.
DR EMBL; AL606999; CAE04846.2; -; Genomic_DNA.
DR EMBL; AP014960; BAS91481.1; -; Genomic_DNA.
DR RefSeq; XP_015635371.1; XM_015779885.1.
DR AlphaFoldDB; Q7XM13; -.
DR SMR; Q7XM13; -.
DR IntAct; Q7XM13; 1.
DR STRING; 4530.OS04T0663600-00; -.
DR PaxDb; Q7XM13; -.
DR EnsemblPlants; Os04t0663600-01; Os04t0663600-01; Os04g0663600.
DR GeneID; 107275471; -.
DR Gramene; Os04t0663600-01; Os04t0663600-01; Os04g0663600.
DR KEGG; osa:107275471; -.
DR eggNOG; ENOG502QRYV; Eukaryota.
DR HOGENOM; CLU_074227_0_0_1; -.
DR InParanoid; Q7XM13; -.
DR OMA; RELYYSC; -.
DR OrthoDB; 1471673at2759; -.
DR Proteomes; UP000000763; Chromosome 4.
DR Proteomes; UP000059680; Chromosome 4.
DR Genevisible; Q7XM13; OS.
DR GO; GO:0005634; C:nucleus; IDA:UniProtKB.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0090506; P:axillary shoot meristem initiation; IMP:UniProtKB.
DR GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IDA:UniProtKB.
DR GO; GO:0099402; P:plant organ development; IEA:InterPro.
DR CDD; cd00086; homeodomain; 1.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR001356; Homeobox_dom.
DR InterPro; IPR044555; WUSCHEL-like.
DR PANTHER; PTHR45940; PTHR45940; 1.
DR Pfam; PF00046; Homeodomain; 1.
DR SMART; SM00389; HOX; 1.
DR SUPFAM; SSF46689; SSF46689; 1.
DR PROSITE; PS50071; HOMEOBOX_2; 1.
PE 1: Evidence at protein level;
KW Developmental protein; DNA-binding; Homeobox; Nucleus; Reference proteome;
KW Transcription; Transcription regulation.
FT CHAIN 1..289
FT /note="WUSCHEL-related homeobox 1"
FT /id="PRO_0000308632"
FT DNA_BIND 31..96
FT /note="Homeobox; WUS-type"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00108"
FT REGION 1..34
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MUTAGEN 79..85
FT /note="Missing: In srt1; defects in tiller formation and
FT complete female sterility."
FT /evidence="ECO:0000269|PubMed:27194802"
FT CONFLICT 177..182
FT /note="VGCAAG -> GGGADA (in Ref. 1; BAE48303)"
FT /evidence="ECO:0000305"
FT CONFLICT 206..208
FT /note="VFV -> GGG (in Ref. 1; BAE48303)"
FT /evidence="ECO:0000305"
FT CONFLICT 218
FT /note="V -> G (in Ref. 1; BAE48303)"
FT /evidence="ECO:0000305"
FT CONFLICT 236
FT /note="S -> T (in Ref. 1; BAE48303)"
FT /evidence="ECO:0000305"
FT CONFLICT 237
FT /note="N -> Y (in Ref. 2; CAJ84138 and 3; CAE04846)"
SQ SEQUENCE 289 AA; 30954 MW; 5952E631B589F301 CRC64;
MDHMQQQQRQ QVGGGGGEEV AGRGGVPVCR PSGTRWTPTT EQIKILRELY YSCGIRSPNS
EQIQRIAAML RQYGRIEGKN VFYWFQNHKA RERQKKRLTT LDVTTTTAAA ADADASHLAV
LSLSPTAAGA TAPSFPGFYV GNGGAVQTDQ ANVVNWDCTA MAAEKTFLQD YMGVSGVGCA
AGAAPTPWAM TTTTREPETL PLFPVVFVGG DGAHRHAVHG GFPSNFQRWG SAAATSNTIT
VQQHLQQHNF YSSSSSQLHS QDGPAAGTSL ELTLSSYYCS CSPYPAGSM
