WOX3_ARATH
ID WOX3_ARATH Reviewed; 244 AA.
AC Q9SIB4;
DT 15-MAR-2005, integrated into UniProtKB/Swiss-Prot.
DT 01-MAY-2000, sequence version 1.
DT 03-AUG-2022, entry version 142.
DE RecName: Full=WUSCHEL-related homeobox 3;
DE AltName: Full=Protein PRESSED FLOWER;
GN Name=WOX3; Synonyms=PRS; OrderedLocusNames=At2g28610; ORFNames=T8O18.10;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA], FUNCTION, TISSUE SPECIFICITY, AND DEVELOPMENTAL
RP STAGE.
RC STRAIN=cv. Landsberg erecta;
RX PubMed=11751640; DOI=10.1101/gad.931001;
RA Matsumoto N., Okada K.;
RT "A homeobox gene, PRESSED FLOWER, regulates lateral axis-dependent
RT development of Arabidopsis flowers.";
RL Genes Dev. 15:3355-3364(2001).
RN [2]
RP ERRATUM OF PUBMED:11751640.
RA Matsumoto N., Okada K.;
RL Genes Dev. 16:764-764(2002).
RN [3]
RP NUCLEOTIDE SEQUENCE [MRNA], AND DEVELOPMENTAL STAGE.
RC STRAIN=cv. Landsberg erecta;
RX PubMed=14711878; DOI=10.1242/dev.00963;
RA Haecker A., Gross-Hardt R., Geiges B., Sarkar A., Breuninger H.,
RA Herrmann M., Laux T.;
RT "Expression dynamics of WOX genes mark cell fate decisions during early
RT embryonic patterning in Arabidopsis thaliana.";
RL Development 131:657-668(2004).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10617197; DOI=10.1038/45471;
RA Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D.,
RA Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V.,
RA Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H.L., Moffat K.S.,
RA Cronin L.A., Shen M., Pai G., Van Aken S., Umayam L., Tallon L.J.,
RA Gill J.E., Adams M.D., Carrera A.J., Creasy T.H., Goodman H.M.,
RA Somerville C.R., Copenhaver G.P., Preuss D., Nierman W.C., White O.,
RA Eisen J.A., Salzberg S.L., Fraser C.M., Venter J.C.;
RT "Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana.";
RL Nature 402:761-768(1999).
RN [5]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [6]
RP FUNCTION.
RX PubMed=15169755; DOI=10.1242/dev.01164;
RA Nardmann J., Ji J., Werr W., Scanlon M.J.;
RT "The maize duplicate genes narrow sheath1 and narrow sheath2 encode a
RT conserved homeobox gene function in a lateral domain of shoot apical
RT meristems.";
RL Development 131:2827-2839(2004).
CC -!- FUNCTION: Probable transcription factor required to initiate organ
CC founder cells in a lateral domain of shoot meristems. Involved in the
CC lateral sepal axis-dependent development of flowers, probably by
CC regulating the proliferation of L1 cells at the lateral region of
CC flower primordia. Required for the formation of the margin cells of the
CC first and second whorl organs. {ECO:0000269|PubMed:11751640,
CC ECO:0000269|PubMed:15169755}.
CC -!- INTERACTION:
CC Q9SIB4; Q8LPR5: TCP4; NbExp=3; IntAct=EBI-15199115, EBI-15192325;
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
CC -!- TISSUE SPECIFICITY: Expressed in aerial parts of seedlings,
CC inflorescences and flowers at low level. Expressed in a restricted
CC number of L1 cells at the lateral regions of flower primordia.
CC {ECO:0000269|PubMed:11751640}.
CC -!- DEVELOPMENTAL STAGE: First expressed in the L1 cells of the lateral
CC regions of a flower primordium at early stage 1, in which the lateral
CC sepals are expected to develop at a later stage. It then rapidly
CC decreases at the late stage 1 and disappears at stage 2. At stage 3, it
CC reappears in all four-sepal young primordia. Not detected at the
CC central zone of the inflorescence meristem and the floral meristem. In
CC stages 4 through 6, when four sepals develop to enclose the flower bud,
CC it is localized at the lateral edges of the four sepals and forms an
CC arch of the L1 cells at the margin of sepals. Expressed in the young
CC primordia of petals and stamens. As the petals and stamens develop, it
CC is limited at the margins of petals and stamens in a way similar to
CC that of sepals. In the vegetative phase, it is expressed at the lateral
CC regions of young leaf primordia, as well as in flowers and floral
CC organs. {ECO:0000269|PubMed:11751640, ECO:0000269|PubMed:14711878}.
CC -!- SIMILARITY: Belongs to the WUS homeobox family. {ECO:0000305}.
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DR EMBL; AB058920; BAB79446.1; -; mRNA.
DR EMBL; AY251397; AAP37135.1; -; mRNA.
DR EMBL; AC007171; AAD24374.1; -; Genomic_DNA.
DR EMBL; CP002685; AEC08149.1; -; Genomic_DNA.
DR PIR; A84687; A84687.
DR RefSeq; NP_180429.1; NM_128422.3.
DR AlphaFoldDB; Q9SIB4; -.
DR SMR; Q9SIB4; -.
DR BioGRID; 2760; 9.
DR IntAct; Q9SIB4; 9.
DR STRING; 3702.AT2G28610.1; -.
DR PaxDb; Q9SIB4; -.
DR PRIDE; Q9SIB4; -.
DR EnsemblPlants; AT2G28610.1; AT2G28610.1; AT2G28610.
DR GeneID; 817410; -.
DR Gramene; AT2G28610.1; AT2G28610.1; AT2G28610.
DR KEGG; ath:AT2G28610; -.
DR Araport; AT2G28610; -.
DR TAIR; locus:2065484; AT2G28610.
DR eggNOG; ENOG502S13K; Eukaryota.
DR HOGENOM; CLU_070454_1_0_1; -.
DR InParanoid; Q9SIB4; -.
DR OMA; MNEYYCT; -.
DR OrthoDB; 1551465at2759; -.
DR PRO; PR:Q9SIB4; -.
DR Proteomes; UP000006548; Chromosome 2.
DR ExpressionAtlas; Q9SIB4; baseline and differential.
DR Genevisible; Q9SIB4; AT.
DR GO; GO:0005634; C:nucleus; IDA:TAIR.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; ISS:TAIR.
DR GO; GO:0009943; P:adaxial/abaxial axis specification; IMP:TAIR.
DR GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR GO; GO:0009947; P:centrolateral axis specification; IMP:TAIR.
DR GO; GO:0009908; P:flower development; IMP:TAIR.
DR GO; GO:0099402; P:plant organ development; IGI:TAIR.
DR GO; GO:0010482; P:regulation of epidermal cell division; IMP:TAIR.
DR GO; GO:0010865; P:stipule development; IMP:TAIR.
DR CDD; cd00086; homeodomain; 1.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR001356; Homeobox_dom.
DR InterPro; IPR044555; WUSCHEL-like.
DR PANTHER; PTHR45940; PTHR45940; 1.
DR Pfam; PF00046; Homeodomain; 1.
DR SMART; SM00389; HOX; 1.
DR SUPFAM; SSF46689; SSF46689; 1.
DR PROSITE; PS50071; HOMEOBOX_2; 1.
PE 1: Evidence at protein level;
KW Developmental protein; Differentiation; DNA-binding; Flowering; Homeobox;
KW Nucleus; Reference proteome; Transcription; Transcription regulation.
FT CHAIN 1..244
FT /note="WUSCHEL-related homeobox 3"
FT /id="PRO_0000049367"
FT DNA_BIND 4..68
FT /note="Homeobox; WUS-type"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00108"
SQ SEQUENCE 244 AA; 28134 MW; 983C19D4F0DCF828 CRC64;
MSPVASTRWC PTPEQLMILE EMYRSGIRTP NAVQIQQITA HLAFYGRIEG KNVFYWFQNH
KARDRQKLRK KLAKQLHQQQ HQLQLQLQQI KPKPISSMIS QPVNKNIIDH HNPYHHHHHN
HHHNHHRPYD HMSFDCCSHP SPMCLPHQGT GVGEAPSKVM NEYYCTKSGA EEILMQKSIT
GPNSSYGRDW MMMMDMGPRP SYPSSSSSPI SCCNMMMSSP KIPLKTLELF PISSINSKQD
STKL
