WRK11_ARATH
ID WRK11_ARATH Reviewed; 325 AA.
AC Q9SV15; Q8H1G1; Q93YX0;
DT 11-APR-2003, integrated into UniProtKB/Swiss-Prot.
DT 15-DEC-2003, sequence version 2.
DT 03-AUG-2022, entry version 153.
DE RecName: Full=Probable WRKY transcription factor 11;
DE AltName: Full=WRKY DNA-binding protein 11;
GN Name=WRKY11; OrderedLocusNames=At4g31550; ORFNames=F3L17.120;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1).
RC STRAIN=cv. Columbia; TISSUE=Flower;
RA Ulker B., Kushnir S., Somssich I.E.;
RL Submitted (AUG-2001) to the EMBL/GenBank/DDBJ databases.
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10617198; DOI=10.1038/47134;
RA Mayer K.F.X., Schueller C., Wambutt R., Murphy G., Volckaert G., Pohl T.,
RA Duesterhoeft A., Stiekema W., Entian K.-D., Terryn N., Harris B.,
RA Ansorge W., Brandt P., Grivell L.A., Rieger M., Weichselgartner M.,
RA de Simone V., Obermaier B., Mache R., Mueller M., Kreis M., Delseny M.,
RA Puigdomenech P., Watson M., Schmidtheini T., Reichert B., Portetelle D.,
RA Perez-Alonso M., Boutry M., Bancroft I., Vos P., Hoheisel J.,
RA Zimmermann W., Wedler H., Ridley P., Langham S.-A., McCullagh B.,
RA Bilham L., Robben J., van der Schueren J., Grymonprez B., Chuang Y.-J.,
RA Vandenbussche F., Braeken M., Weltjens I., Voet M., Bastiaens I., Aert R.,
RA Defoor E., Weitzenegger T., Bothe G., Ramsperger U., Hilbert H., Braun M.,
RA Holzer E., Brandt A., Peters S., van Staveren M., Dirkse W., Mooijman P.,
RA Klein Lankhorst R., Rose M., Hauf J., Koetter P., Berneiser S., Hempel S.,
RA Feldpausch M., Lamberth S., Van den Daele H., De Keyser A., Buysshaert C.,
RA Gielen J., Villarroel R., De Clercq R., van Montagu M., Rogers J.,
RA Cronin A., Quail M.A., Bray-Allen S., Clark L., Doggett J., Hall S.,
RA Kay M., Lennard N., McLay K., Mayes R., Pettett A., Rajandream M.A.,
RA Lyne M., Benes V., Rechmann S., Borkova D., Bloecker H., Scharfe M.,
RA Grimm M., Loehnert T.-H., Dose S., de Haan M., Maarse A.C., Schaefer M.,
RA Mueller-Auer S., Gabel C., Fuchs M., Fartmann B., Granderath K., Dauner D.,
RA Herzl A., Neumann S., Argiriou A., Vitale D., Liguori R., Piravandi E.,
RA Massenet O., Quigley F., Clabauld G., Muendlein A., Felber R., Schnabl S.,
RA Hiller R., Schmidt W., Lecharny A., Aubourg S., Chefdor F., Cooke R.,
RA Berger C., Monfort A., Casacuberta E., Gibbons T., Weber N., Vandenbol M.,
RA Bargues M., Terol J., Torres A., Perez-Perez A., Purnelle B., Bent E.,
RA Johnson S., Tacon D., Jesse T., Heijnen L., Schwarz S., Scholler P.,
RA Heber S., Francs P., Bielke C., Frishman D., Haase D., Lemcke K.,
RA Mewes H.-W., Stocker S., Zaccaria P., Bevan M., Wilson R.K.,
RA de la Bastide M., Habermann K., Parnell L., Dedhia N., Gnoj L., Schutz K.,
RA Huang E., Spiegel L., Sekhon M., Murray J., Sheet P., Cordes M.,
RA Abu-Threideh J., Stoneking T., Kalicki J., Graves T., Harmon G.,
RA Edwards J., Latreille P., Courtney L., Cloud J., Abbott A., Scott K.,
RA Johnson D., Minx P., Bentley D., Fulton B., Miller N., Greco T., Kemp K.,
RA Kramer J., Fulton L., Mardis E., Dante M., Pepin K., Hillier L.W.,
RA Nelson J., Spieth J., Ryan E., Andrews S., Geisel C., Layman D., Du H.,
RA Ali J., Berghoff A., Jones K., Drone K., Cotton M., Joshu C., Antonoiu B.,
RA Zidanic M., Strong C., Sun H., Lamar B., Yordan C., Ma P., Zhong J.,
RA Preston R., Vil D., Shekher M., Matero A., Shah R., Swaby I.K.,
RA O'Shaughnessy A., Rodriguez M., Hoffman J., Till S., Granat S., Shohdy N.,
RA Hasegawa A., Hameed A., Lodhi M., Johnson A., Chen E., Marra M.A.,
RA Martienssen R., McCombie W.R.;
RT "Sequence and analysis of chromosome 4 of the plant Arabidopsis thaliana.";
RL Nature 402:769-777(1999).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2).
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [5]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2).
RA Brover V.V., Troukhan M.E., Alexandrov N.A., Lu Y.-P., Flavell R.B.,
RA Feldmann K.A.;
RT "Full-length cDNA from Arabidopsis thaliana.";
RL Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases.
RN [6]
RP TISSUE SPECIFICITY, AND INDUCTION.
RX PubMed=11722756; DOI=10.1046/j.1365-313x.2001.01131.x;
RA Robatzek S., Somssich I.E.;
RT "A new member of the Arabidopsis WRKY transcription factor family, AtWRKY6,
RT is associated with both senescence- and defence-related processes.";
RL Plant J. 28:123-133(2001).
RN [7]
RP FUNCTION, DISRUPTION PHENOTYPE, REPRESSION BY BACILLUS CEREUS AND
RP PSEUDOMONAS FLUORESCENS, AND SUBCELLULAR LOCATION.
RC STRAIN=cv. Columbia;
RX PubMed=26433201; DOI=10.1093/jxb/erv445;
RA Jiang C.-H., Huang Z.-Y., Xie P., Gu C., Li K., Wang D.-C., Yu Y.-Y.,
RA Fan Z.-H., Wang C.-J., Wang Y.-P., Guo Y.-H., Guo J.-H.;
RT "Transcription factors WRKY70 and WRKY11 served as regulators in
RT rhizobacterium Bacillus cereus AR156-induced systemic resistance to
RT Pseudomonas syringae pv. tomato DC3000 in Arabidopsis.";
RL J. Exp. Bot. 67:157-174(2016).
CC -!- FUNCTION: Transcription factor. Interacts specifically with the W box
CC (5'-(T)TGAC[CT]-3'), a frequently occurring elicitor-responsive cis-
CC acting element (By similarity). Regulates rhizobacterium B.cereus
CC AR156-induced systemic resistance (ISR) to P.syringae pv. tomato
CC DC3000, probably by activating the jasmonic acid (JA)- signaling
CC pathway (PubMed:26433201). {ECO:0000250, ECO:0000269|PubMed:26433201}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00223,
CC ECO:0000269|PubMed:26433201}.
CC -!- ALTERNATIVE PRODUCTS:
CC Event=Alternative splicing; Named isoforms=2;
CC Name=1;
CC IsoId=Q9SV15-1; Sequence=Displayed;
CC Name=2;
CC IsoId=Q9SV15-2; Sequence=VSP_009108;
CC -!- TISSUE SPECIFICITY: In young, mature and senescent leaves.
CC {ECO:0000269|PubMed:11722756}.
CC -!- INDUCTION: Strongly during leaf senescence (PubMed:11722756). Repressed
CC by rhizobacterium B.cereus AR156 in leaves, and to a lower extent, by
CC P.fluorescens WCS417r (PubMed:26433201). {ECO:0000269|PubMed:11722756,
CC ECO:0000269|PubMed:26433201}.
CC -!- DISRUPTION PHENOTYPE: Reduced rhizobacterium B.cereus AR156-induced
CC systemic resistance (ISR) to P.syringae pv. tomato DC3000 associated
CC with reduced jasmonic acid (JA)-mediated signal pathway. Plants lacking
CC both WRKY11 and WRKY70 are totally impaired in B.cereus AR156-mediated
CC ISR. {ECO:0000269|PubMed:26433201}.
CC -!- SIMILARITY: Belongs to the WRKY group II-d family. {ECO:0000305}.
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DR EMBL; AF404856; AAK96194.1; -; mRNA.
DR EMBL; AL080283; CAB45914.1; -; Genomic_DNA.
DR EMBL; AL161579; CAB79873.1; -; Genomic_DNA.
DR EMBL; CP002687; AEE85927.1; -; Genomic_DNA.
DR EMBL; CP002687; AEE85928.1; -; Genomic_DNA.
DR EMBL; AY059731; AAL24088.1; -; mRNA.
DR EMBL; AY150394; AAN12939.1; -; mRNA.
DR EMBL; BT001100; AAN64164.1; -; mRNA.
DR EMBL; AY084855; AAM61419.1; -; mRNA.
DR PIR; T10685; T10685.
DR RefSeq; NP_567878.2; NM_119304.4. [Q9SV15-2]
DR RefSeq; NP_849559.1; NM_179228.2. [Q9SV15-1]
DR AlphaFoldDB; Q9SV15; -.
DR SMR; Q9SV15; -.
DR BioGRID; 14568; 4.
DR IntAct; Q9SV15; 4.
DR MINT; Q9SV15; -.
DR STRING; 3702.AT4G31550.1; -.
DR PaxDb; Q9SV15; -.
DR PRIDE; Q9SV15; -.
DR ProteomicsDB; 234257; -. [Q9SV15-1]
DR EnsemblPlants; AT4G31550.1; AT4G31550.1; AT4G31550. [Q9SV15-1]
DR EnsemblPlants; AT4G31550.2; AT4G31550.2; AT4G31550. [Q9SV15-2]
DR GeneID; 829282; -.
DR Gramene; AT4G31550.1; AT4G31550.1; AT4G31550. [Q9SV15-1]
DR Gramene; AT4G31550.2; AT4G31550.2; AT4G31550. [Q9SV15-2]
DR KEGG; ath:AT4G31550; -.
DR Araport; AT4G31550; -.
DR TAIR; locus:2125239; AT4G31550.
DR eggNOG; ENOG502QR3I; Eukaryota.
DR InParanoid; Q9SV15; -.
DR OrthoDB; 1111662at2759; -.
DR PhylomeDB; Q9SV15; -.
DR PRO; PR:Q9SV15; -.
DR Proteomes; UP000006548; Chromosome 4.
DR ExpressionAtlas; Q9SV15; baseline and differential.
DR Genevisible; Q9SV15; AT.
DR GO; GO:0005634; C:nucleus; IDA:UniProtKB.
DR GO; GO:0005516; F:calmodulin binding; IDA:TAIR.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; ISS:TAIR.
DR GO; GO:0000976; F:transcription cis-regulatory region binding; IPI:TAIR.
DR GO; GO:0042742; P:defense response to bacterium; IMP:UniProtKB.
DR GO; GO:0009682; P:induced systemic resistance; IMP:UniProtKB.
DR GO; GO:2000022; P:regulation of jasmonic acid mediated signaling pathway; IDA:UniProtKB.
DR GO; GO:0009617; P:response to bacterium; IEP:UniProtKB.
DR Gene3D; 2.20.25.80; -; 1.
DR InterPro; IPR003657; WRKY_dom.
DR InterPro; IPR036576; WRKY_dom_sf.
DR InterPro; IPR044810; WRKY_plant.
DR InterPro; IPR018872; Zn-cluster-dom.
DR PANTHER; PTHR31282; PTHR31282; 1.
DR Pfam; PF10533; Plant_zn_clust; 1.
DR Pfam; PF03106; WRKY; 1.
DR SMART; SM00774; WRKY; 1.
DR SUPFAM; SSF118290; SSF118290; 1.
DR PROSITE; PS50811; WRKY; 1.
PE 2: Evidence at transcript level;
KW Alternative splicing; DNA-binding; Jasmonic acid signaling pathway;
KW Nucleus; Plant defense; Reference proteome; Transcription;
KW Transcription regulation.
FT CHAIN 1..325
FT /note="Probable WRKY transcription factor 11"
FT /id="PRO_0000133653"
FT DNA_BIND 240..306
FT /note="WRKY"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00223"
FT VAR_SEQ 223
FT /note="Missing (in isoform 2)"
FT /evidence="ECO:0000303|PubMed:14593172, ECO:0000303|Ref.5"
FT /id="VSP_009108"
FT CONFLICT 268
FT /note="Y -> N (in Ref. 4; AAL24088)"
FT /evidence="ECO:0000305"
FT CONFLICT 291
FT /note="Missing (in Ref. 5; AAM61419)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 325 AA; 35805 MW; 2DB2B296D776EDC6 CRC64;
MAVDLMRFPK IDDQTAIQEA ASQGLQSMEH LIRVLSNRPE QQHNVDCSEI TDFTVSKFKT
VISLLNRTGH ARFRRGPVHS TSSAASQKLQ SQIVKNTQPE APIVRTTTNH PQIVPPPSSV
TLDFSKPSIF GTKAKSAELE FSKENFSVSL NSSFMSSAIT GDGSVSNGKI FLASAPLQPV
NSSGKPPLAG HPYRKRCLEH EHSESFSGKV SGSAYGKCHC KKSRKNRMKR TVRVPAISAK
IADIPPDEYS WRKYGQKPIK GSPHPRGYYK CSTFRGCPAR KHVERALDDP AMLIVTYEGE
HRHNQSAMQE NISSSGINDL VFASA
