WRK21_ARATH
ID WRK21_ARATH Reviewed; 380 AA.
AC O04336;
DT 15-MAY-2002, integrated into UniProtKB/Swiss-Prot.
DT 01-JUL-1997, sequence version 1.
DT 25-MAY-2022, entry version 156.
DE RecName: Full=Probable WRKY transcription factor 21;
DE AltName: Full=WRKY DNA-binding protein 21;
GN Name=WRKY21; OrderedLocusNames=At2g30590; ORFNames=T06B20.6, T6B20.6;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE, AND INDUCTION.
RX PubMed=11449049; DOI=10.2307/3871384;
RA Yu D., Chen C., Chen Z.;
RT "Evidence for an important role of WRKY DNA binding proteins in the
RT regulation of NPR1 gene expression.";
RL Plant Cell 13:1527-1540(2001).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10617197; DOI=10.1038/45471;
RA Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D.,
RA Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V.,
RA Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H.L., Moffat K.S.,
RA Cronin L.A., Shen M., Pai G., Van Aken S., Umayam L., Tallon L.J.,
RA Gill J.E., Adams M.D., Carrera A.J., Creasy T.H., Goodman H.M.,
RA Somerville C.R., Copenhaver G.P., Preuss D., Nierman W.C., White O.,
RA Eisen J.A., Salzberg S.L., Fraser C.M., Venter J.C.;
RT "Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana.";
RL Nature 402:761-768(1999).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
CC -!- FUNCTION: Transcription factor. Interacts specifically with the W box
CC (5'-(T)TGAC[CT]-3'), a frequently occurring elicitor-responsive cis-
CC acting element (By similarity). {ECO:0000250}.
CC -!- INTERACTION:
CC O04336; O80575: At2g44050; NbExp=3; IntAct=EBI-1239118, EBI-4473692;
CC O04336; O24410: IAA20; NbExp=3; IntAct=EBI-1239118, EBI-632272;
CC O04336; Q9M1R4: IAA30; NbExp=3; IntAct=EBI-1239118, EBI-3946710;
CC O04336; O22179: MYB70; NbExp=3; IntAct=EBI-1239118, EBI-1238013;
CC O04336; O23160: MYB73; NbExp=3; IntAct=EBI-1239118, EBI-25506855;
CC O04336; Q9SLH3: RGA; NbExp=3; IntAct=EBI-1239118, EBI-963624;
CC O04336; Q9LQF0: TCP23; NbExp=3; IntAct=EBI-1239118, EBI-15192297;
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
CC -!- INDUCTION: By salicylic acid. {ECO:0000269|PubMed:11449049}.
CC -!- SIMILARITY: Belongs to the WRKY group II-d family. {ECO:0000305}.
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DR EMBL; AF272747; AAK28441.1; -; mRNA.
DR EMBL; U93215; AAB63078.1; -; Genomic_DNA.
DR EMBL; CP002685; AEC08412.1; -; Genomic_DNA.
DR EMBL; BT000231; AAN15550.1; -; mRNA.
DR EMBL; AY136441; AAM97106.1; -; mRNA.
DR PIR; C84710; C84710.
DR RefSeq; NP_565703.1; NM_128611.3.
DR AlphaFoldDB; O04336; -.
DR SMR; O04336; -.
DR BioGRID; 2958; 18.
DR IntAct; O04336; 18.
DR MINT; O04336; -.
DR STRING; 3702.AT2G30590.1; -.
DR PaxDb; O04336; -.
DR PRIDE; O04336; -.
DR ProteomicsDB; 234362; -.
DR EnsemblPlants; AT2G30590.1; AT2G30590.1; AT2G30590.
DR GeneID; 817609; -.
DR Gramene; AT2G30590.1; AT2G30590.1; AT2G30590.
DR KEGG; ath:AT2G30590; -.
DR Araport; AT2G30590; -.
DR TAIR; locus:2064377; AT2G30590.
DR eggNOG; ENOG502QPQX; Eukaryota.
DR HOGENOM; CLU_040478_0_0_1; -.
DR InParanoid; O04336; -.
DR OMA; NCHRVIS; -.
DR OrthoDB; 1163269at2759; -.
DR PhylomeDB; O04336; -.
DR PRO; PR:O04336; -.
DR Proteomes; UP000006548; Chromosome 2.
DR ExpressionAtlas; O04336; baseline and differential.
DR Genevisible; O04336; AT.
DR GO; GO:0005634; C:nucleus; IC:TAIR.
DR GO; GO:0005516; F:calmodulin binding; IDA:TAIR.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; ISS:TAIR.
DR GO; GO:0000976; F:transcription cis-regulatory region binding; IPI:TAIR.
DR GO; GO:0019760; P:glucosinolate metabolic process; IMP:TAIR.
DR Gene3D; 2.20.25.80; -; 1.
DR InterPro; IPR003657; WRKY_dom.
DR InterPro; IPR036576; WRKY_dom_sf.
DR InterPro; IPR044810; WRKY_plant.
DR InterPro; IPR018872; Zn-cluster-dom.
DR PANTHER; PTHR31282; PTHR31282; 2.
DR Pfam; PF10533; Plant_zn_clust; 1.
DR Pfam; PF03106; WRKY; 1.
DR SMART; SM00774; WRKY; 1.
DR SUPFAM; SSF118290; SSF118290; 1.
DR PROSITE; PS50811; WRKY; 1.
PE 1: Evidence at protein level;
KW DNA-binding; Nucleus; Reference proteome; Transcription;
KW Transcription regulation.
FT CHAIN 1..380
FT /note="Probable WRKY transcription factor 21"
FT /id="PRO_0000133663"
FT DNA_BIND 307..373
FT /note="WRKY"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00223"
FT REGION 84..107
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 139..196
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 139..181
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 380 AA; 43005 MW; AEE49BFD6E6FD797 CRC64;
MEEIEGTNRA AVESCHRVLN LLHRSQQQDH VGFEKNLVSE TREAVIRFKR VGSLLSSSVG
HARFRRAKKL QSHVSQSLLL DPCQQRTTEV PSSSSQKTPV LRSGFQELSL RQPSDSLTLG
TRSFSLNSNA KAPLLQLNQQ TMPPSNYPTL FPVQQQQQQQ QQQQQQEQQQ QQQQQQQQFH
ERLQAHHLHQ QQQLQKHQAE LMLRKCNGGI SLSFDNSSCT PTMSSTRSFV SSLSIDGSVA
NIEGKNSFHF GVPSSTDQNS LHSKRKCPLK GDEHGSLKCG SSSRCHCAKK RKHRVRRSIR
VPAISNKVAD IPPDDYSWRK YGQKPIKGSP YPRGYYKCSS MRGCPARKHV ERCLEDPAML
IVTYEAEHNH PKLPSQAITT
