WRK43_ARATH
ID WRK43_ARATH Reviewed; 109 AA.
AC Q8GY11; F4IH91; O82356; Q8VWZ0;
DT 11-APR-2003, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2003, sequence version 1.
DT 03-AUG-2022, entry version 138.
DE RecName: Full=Probable WRKY transcription factor 43;
DE AltName: Full=WRKY DNA-binding protein 43;
GN Name=WRKY43; OrderedLocusNames=At2g46130; ORFNames=T3F17.22;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10617197; DOI=10.1038/45471;
RA Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D.,
RA Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V.,
RA Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H.L., Moffat K.S.,
RA Cronin L.A., Shen M., Pai G., Van Aken S., Umayam L., Tallon L.J.,
RA Gill J.E., Adams M.D., Carrera A.J., Creasy T.H., Goodman H.M.,
RA Somerville C.R., Copenhaver G.P., Preuss D., Nierman W.C., White O.,
RA Eisen J.A., Salzberg S.L., Fraser C.M., Venter J.C.;
RT "Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana.";
RL Nature 402:761-768(1999).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
RC STRAIN=cv. Columbia;
RX PubMed=11910074; DOI=10.1126/science.1071006;
RA Seki M., Narusaka M., Kamiya A., Ishida J., Satou M., Sakurai T.,
RA Nakajima M., Enju A., Akiyama K., Oono Y., Muramatsu M., Hayashizaki Y.,
RA Kawai J., Carninci P., Itoh M., Ishii Y., Arakawa T., Shibata K.,
RA Shinagawa A., Shinozaki K.;
RT "Functional annotation of a full-length Arabidopsis cDNA collection.";
RL Science 296:141-145(2002).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [5]
RP NUCLEOTIDE SEQUENCE [MRNA] OF 13-109 (ISOFORMS 1 AND 2).
RC STRAIN=cv. Columbia; TISSUE=Flower;
RA Ulker B., Kushnir S., Somssich I.E.;
RL Submitted (OCT-2001) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Transcription factor. Interacts specifically with the W box
CC (5'-(T)TGAC[CT]-3'), a frequently occurring elicitor-responsive cis-
CC acting element (By similarity). {ECO:0000250}.
CC -!- INTERACTION:
CC Q8GY11; P25854: CAM4; NbExp=2; IntAct=EBI-1235953, EBI-1235664;
CC Q8GY11; Q9LQF0: TCP23; NbExp=3; IntAct=EBI-1235953, EBI-15192297;
CC Q8GY11; Q9SZG3: VQ29; NbExp=3; IntAct=EBI-1235953, EBI-25517843;
CC Q8GY11; Q9FNP0: VQ31; NbExp=3; IntAct=EBI-1235953, EBI-25517821;
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
CC -!- ALTERNATIVE PRODUCTS:
CC Event=Alternative splicing; Named isoforms=2;
CC Name=1;
CC IsoId=Q8GY11-1; Sequence=Displayed;
CC Name=2;
CC IsoId=Q8GY11-2; Sequence=VSP_007129;
CC -!- SIMILARITY: Belongs to the WRKY group II-c family. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAC62892.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR EMBL; AC005397; AAC62892.1; ALT_INIT; Genomic_DNA.
DR EMBL; CP002685; AEC10646.1; -; Genomic_DNA.
DR EMBL; CP002685; AEC10647.2; -; Genomic_DNA.
DR EMBL; AK117931; BAC42569.1; -; mRNA.
DR EMBL; BT004701; AAO42947.1; -; mRNA.
DR EMBL; AF404861; AAK96199.1; -; mRNA.
DR EMBL; AF442391; AAL35284.1; -; mRNA.
DR PIR; A84899; A84899.
DR RefSeq; NP_182136.2; NM_130175.3. [Q8GY11-1]
DR RefSeq; NP_850446.2; NM_180115.2. [Q8GY11-2]
DR AlphaFoldDB; Q8GY11; -.
DR SMR; Q8GY11; -.
DR BioGRID; 4555; 25.
DR IntAct; Q8GY11; 26.
DR STRING; 3702.AT2G46130.1; -.
DR iPTMnet; Q8GY11; -.
DR PaxDb; Q8GY11; -.
DR PRIDE; Q8GY11; -.
DR EnsemblPlants; AT2G46130.1; AT2G46130.1; AT2G46130. [Q8GY11-1]
DR EnsemblPlants; AT2G46130.2; AT2G46130.2; AT2G46130. [Q8GY11-2]
DR GeneID; 819220; -.
DR Gramene; AT2G46130.1; AT2G46130.1; AT2G46130. [Q8GY11-1]
DR Gramene; AT2G46130.2; AT2G46130.2; AT2G46130. [Q8GY11-2]
DR KEGG; ath:AT2G46130; -.
DR Araport; AT2G46130; -.
DR TAIR; locus:2062949; AT2G46130.
DR eggNOG; ENOG502RXZS; Eukaryota.
DR InParanoid; Q8GY11; -.
DR OMA; YRCTQHM; -.
DR OrthoDB; 1289791at2759; -.
DR PhylomeDB; Q8GY11; -.
DR PRO; PR:Q8GY11; -.
DR Proteomes; UP000006548; Chromosome 2.
DR ExpressionAtlas; Q8GY11; baseline and differential.
DR Genevisible; Q8GY11; AT.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; ISS:TAIR.
DR GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR Gene3D; 2.20.25.80; -; 1.
DR InterPro; IPR003657; WRKY_dom.
DR InterPro; IPR036576; WRKY_dom_sf.
DR InterPro; IPR044810; WRKY_plant.
DR PANTHER; PTHR31221; PTHR31221; 1.
DR Pfam; PF03106; WRKY; 1.
DR SMART; SM00774; WRKY; 1.
DR SUPFAM; SSF118290; SSF118290; 1.
DR PROSITE; PS50811; WRKY; 1.
PE 1: Evidence at protein level;
KW Alternative splicing; DNA-binding; Nucleus; Reference proteome;
KW Transcription; Transcription regulation.
FT CHAIN 1..109
FT /note="Probable WRKY transcription factor 43"
FT /id="PRO_0000133684"
FT DNA_BIND 24..89
FT /note="WRKY"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00223"
FT VAR_SEQ 50..53
FT /note="Missing (in isoform 2)"
FT /evidence="ECO:0000303|Ref.5"
FT /id="VSP_007129"
SQ SEQUENCE 109 AA; 12952 MW; 8A0772B1F169491B CRC64;
MNGLVDSSRD KKMKNPRFSF RTKSDADILD DGYRWRKYGQ KSVKNSLYPR SYYRCTQHMC
NVKKQVQRLS KETSIVETTY EGIHNHPCEE LMQTLTPLLH QLQFLSKFT
