WRK51_ARATH
ID WRK51_ARATH Reviewed; 194 AA.
AC Q93WU9; Q9LV96;
DT 11-APR-2003, integrated into UniProtKB/Swiss-Prot.
DT 01-DEC-2001, sequence version 1.
DT 03-AUG-2022, entry version 123.
DE RecName: Full=Probable WRKY transcription factor 51;
DE AltName: Full=WRKY DNA-binding protein 51;
GN Name=WRKY51; OrderedLocusNames=At5g64810; ORFNames=MXK3.3;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RC STRAIN=cv. Columbia; TISSUE=Flower;
RA Kushnir S., Ulker B., Somssich I.E.;
RL Submitted (OCT-2001) to the EMBL/GenBank/DDBJ databases.
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10718197; DOI=10.1093/dnares/7.1.31;
RA Sato S., Nakamura Y., Kaneko T., Katoh T., Asamizu E., Kotani H.,
RA Tabata S.;
RT "Structural analysis of Arabidopsis thaliana chromosome 5. X. Sequence
RT features of the regions of 3,076,755 bp covered by sixty P1 and TAC
RT clones.";
RL DNA Res. 7:31-63(2000).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [4]
RP FUNCTION, AND DISRUPTION PHENOTYPE.
RX PubMed=21030507; DOI=10.1104/pp.110.166876;
RA Gao Q.M., Venugopal S., Navarre D., Kachroo A.;
RT "Low oleic acid-derived repression of jasmonic acid-inducible defense
RT responses requires the WRKY50 and WRKY51 proteins.";
RL Plant Physiol. 155:464-476(2011).
RN [5]
RP INTERACTION WITH CAMBP25/VQ15.
RX PubMed=22535423; DOI=10.1104/pp.112.196816;
RA Cheng Y., Zhou Y., Yang Y., Chi Y.J., Zhou J., Chen J.Y., Wang F., Fan B.,
RA Shi K., Zhou Y.H., Yu J.Q., Chen Z.;
RT "Structural and functional analysis of VQ motif-containing proteins in
RT Arabidopsis as interacting proteins of WRKY transcription factors.";
RL Plant Physiol. 159:810-825(2012).
CC -!- FUNCTION: Transcription factor. Interacts specifically with the W box
CC (5'-(T)TGAC[CT]-3'), a frequently occurring elicitor-responsive cis-
CC acting element (By similarity). Involved in defense responses. May act
CC as positive regulator of salicylic acid (SA)-mediated signaling and
CC negative regulator of jasmonic acid (JA)-mediated signaling
CC (PubMed:21030507). {ECO:0000250, ECO:0000269|PubMed:21030507}.
CC -!- SUBUNIT: Interacts with CAMBP25/VQ15. {ECO:0000269|PubMed:22535423}.
CC -!- INTERACTION:
CC Q93WU9; P46639: KNAT1; NbExp=3; IntAct=EBI-15214372, EBI-530486;
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
CC -!- DISRUPTION PHENOTYPE: No visible phenotype under normal growth
CC conditions. {ECO:0000269|PubMed:21030507}.
CC -!- SIMILARITY: Belongs to the WRKY group II-c family. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=BAA97293.1; Type=Erroneous gene model prediction; Note=The predicted gene At5g64810 has been split into 3 genes: At5g64810, At5g64813 and At5g64816.; Evidence={ECO:0000305};
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AF426252; AAL29429.1; -; mRNA.
DR EMBL; AB019236; BAA97293.1; ALT_SEQ; Genomic_DNA.
DR EMBL; CP002688; AED97953.1; -; Genomic_DNA.
DR RefSeq; NP_568995.2; NM_125877.4.
DR AlphaFoldDB; Q93WU9; -.
DR SMR; Q93WU9; -.
DR BioGRID; 21844; 16.
DR IntAct; Q93WU9; 6.
DR STRING; 3702.AT5G64810.1; -.
DR PaxDb; Q93WU9; -.
DR PRIDE; Q93WU9; -.
DR ProteomicsDB; 234415; -.
DR EnsemblPlants; AT5G64810.1; AT5G64810.1; AT5G64810.
DR GeneID; 836602; -.
DR Gramene; AT5G64810.1; AT5G64810.1; AT5G64810.
DR KEGG; ath:AT5G64810; -.
DR Araport; AT5G64810; -.
DR TAIR; locus:2177639; AT5G64810.
DR eggNOG; ENOG502S01U; Eukaryota.
DR HOGENOM; CLU_073202_3_0_1; -.
DR OMA; DHDNWNQ; -.
DR OrthoDB; 847761at2759; -.
DR PhylomeDB; Q93WU9; -.
DR PRO; PR:Q93WU9; -.
DR Proteomes; UP000006548; Chromosome 5.
DR ExpressionAtlas; Q93WU9; baseline and differential.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; ISS:TAIR.
DR GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR GO; GO:0042742; P:defense response to bacterium; IGI:TAIR.
DR GO; GO:0050832; P:defense response to fungus; IGI:TAIR.
DR GO; GO:0009867; P:jasmonic acid mediated signaling pathway; IGI:TAIR.
DR Gene3D; 2.20.25.80; -; 1.
DR InterPro; IPR003657; WRKY_dom.
DR InterPro; IPR036576; WRKY_dom_sf.
DR InterPro; IPR044810; WRKY_plant.
DR PANTHER; PTHR31221; PTHR31221; 1.
DR Pfam; PF03106; WRKY; 1.
DR SMART; SM00774; WRKY; 1.
DR SUPFAM; SSF118290; SSF118290; 1.
DR PROSITE; PS50811; WRKY; 1.
PE 1: Evidence at protein level;
KW DNA-binding; Nucleus; Plant defense; Reference proteome; Transcription;
KW Transcription regulation.
FT CHAIN 1..194
FT /note="Probable WRKY transcription factor 51"
FT /id="PRO_0000133692"
FT DNA_BIND 104..169
FT /note="WRKY"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00223"
FT REGION 58..97
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 58..79
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 80..97
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 194 AA; 22044 MW; 3F673C154312E11C CRC64;
MNISQNPSPN FTYFSDENFI NPFMDNNDFS NLMFFDIDEG GNNGLIEEEI SSPTSIVSSE
TFTGESGGSG SATTLSKKES TNRGSKESDQ TKETGHRVAF RTRSKIDVMD DGFKWRKYGK
KSVKNNINKR NYYKCSSEGC SVKKRVERDG DDAAYVITTY EGVHNHESLS NVYYNEMVLS
YDHDNWNQHS LLRS
