WRK60_ARATH
ID WRK60_ARATH Reviewed; 271 AA.
AC Q9SK33; Q8VWV4;
DT 15-MAY-2002, integrated into UniProtKB/Swiss-Prot.
DT 01-MAY-2000, sequence version 1.
DT 03-AUG-2022, entry version 131.
DE RecName: Full=Probable WRKY transcription factor 60;
DE AltName: Full=WRKY DNA-binding protein 60;
GN Name=WRKY60; OrderedLocusNames=At2g25000; ORFNames=F27C12.8;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RC STRAIN=cv. C24; TISSUE=Flower;
RA Kushnir S., Ulker B., Somssich I.E.;
RT "Arabidopsis thaliana transcription factor WRKY60.";
RL Submitted (NOV-2001) to the EMBL/GenBank/DDBJ databases.
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10617197; DOI=10.1038/45471;
RA Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D.,
RA Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V.,
RA Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H.L., Moffat K.S.,
RA Cronin L.A., Shen M., Pai G., Van Aken S., Umayam L., Tallon L.J.,
RA Gill J.E., Adams M.D., Carrera A.J., Creasy T.H., Goodman H.M.,
RA Somerville C.R., Copenhaver G.P., Preuss D., Nierman W.C., White O.,
RA Eisen J.A., Salzberg S.L., Fraser C.M., Venter J.C.;
RT "Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana.";
RL Nature 402:761-768(1999).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
CC -!- FUNCTION: Transcription factor. Interacts specifically with the W box
CC (5'-(T)TGAC[CT]-3'), a frequently occurring elicitor-responsive cis-
CC acting element (By similarity). {ECO:0000250}.
CC -!- INTERACTION:
CC Q9SK33; Q9ZNV8: AHP2; NbExp=3; IntAct=EBI-2112777, EBI-1100687;
CC Q9SK33; Q9LNW3: AIP1; NbExp=3; IntAct=EBI-2112777, EBI-1573499;
CC Q9SK33; Q8L9Y3: ARR14; NbExp=3; IntAct=EBI-2112777, EBI-1100737;
CC Q9SK33; Q8L5Y6: CAND1; NbExp=3; IntAct=EBI-2112777, EBI-602912;
CC Q9SK33; Q9LV52: HSFC1; NbExp=3; IntAct=EBI-2112777, EBI-4457746;
CC Q9SK33; Q9LTF2: RPS10C; NbExp=4; IntAct=EBI-2112777, EBI-4458966;
CC Q9SK33; Q9C5T4: WRKY18; NbExp=7; IntAct=EBI-2112777, EBI-1993349;
CC Q9SK33; Q9CAR4: WRKY36; NbExp=3; IntAct=EBI-2112777, EBI-15210240;
CC Q9SK33; Q9SAH7: WRKY40; NbExp=5; IntAct=EBI-2112777, EBI-1993363;
CC Q9SK33; Q9SK33: WRKY60; NbExp=6; IntAct=EBI-2112777, EBI-2112777;
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00223}.
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DR EMBL; AF452177; AAL50787.1; -; mRNA.
DR EMBL; AC006585; AAD23013.1; -; Genomic_DNA.
DR EMBL; CP002685; AEC07648.1; -; Genomic_DNA.
DR EMBL; BT004611; AAO42857.1; -; mRNA.
DR PIR; A84643; A84643.
DR RefSeq; NP_180072.1; NM_128058.4.
DR AlphaFoldDB; Q9SK33; -.
DR SMR; Q9SK33; -.
DR BioGRID; 2391; 35.
DR IntAct; Q9SK33; 34.
DR STRING; 3702.AT2G25000.1; -.
DR PaxDb; Q9SK33; -.
DR PRIDE; Q9SK33; -.
DR ProteomicsDB; 234390; -.
DR EnsemblPlants; AT2G25000.1; AT2G25000.1; AT2G25000.
DR GeneID; 817039; -.
DR Gramene; AT2G25000.1; AT2G25000.1; AT2G25000.
DR KEGG; ath:AT2G25000; -.
DR Araport; AT2G25000; -.
DR TAIR; locus:2047395; AT2G25000.
DR eggNOG; ENOG502QR7M; Eukaryota.
DR HOGENOM; CLU_047067_0_0_1; -.
DR InParanoid; Q9SK33; -.
DR OrthoDB; 1185192at2759; -.
DR PhylomeDB; Q9SK33; -.
DR PRO; PR:Q9SK33; -.
DR Proteomes; UP000006548; Chromosome 2.
DR ExpressionAtlas; Q9SK33; baseline and differential.
DR Genevisible; Q9SK33; AT.
DR GO; GO:0005634; C:nucleus; IDA:TAIR.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; ISS:TAIR.
DR GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR GO; GO:0042742; P:defense response to bacterium; IEP:TAIR.
DR GO; GO:0050832; P:defense response to fungus; IEP:TAIR.
DR GO; GO:0031347; P:regulation of defense response; IMP:TAIR.
DR GO; GO:0002237; P:response to molecule of bacterial origin; IMP:TAIR.
DR GO; GO:0009751; P:response to salicylic acid; IEP:TAIR.
DR Gene3D; 2.20.25.80; -; 1.
DR InterPro; IPR003657; WRKY_dom.
DR InterPro; IPR036576; WRKY_dom_sf.
DR InterPro; IPR044810; WRKY_plant.
DR PANTHER; PTHR31429; PTHR31429; 2.
DR Pfam; PF03106; WRKY; 1.
DR SMART; SM00774; WRKY; 1.
DR SUPFAM; SSF118290; SSF118290; 1.
DR PROSITE; PS50811; WRKY; 1.
PE 1: Evidence at protein level;
KW DNA-binding; Nucleus; Reference proteome; Transcription;
KW Transcription regulation.
FT CHAIN 1..271
FT /note="Probable WRKY transcription factor 60"
FT /id="PRO_0000133701"
FT DNA_BIND 140..206
FT /note="WRKY"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00223"
FT CONFLICT 251
FT /note="P -> S (in Ref. 1; AAL50787)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 271 AA; 30578 MW; 961D79ED693A1260 CRC64;
MDYDPNTNPF DLHFSGKLPK REVSASASKV VEKKWLVKDE KRNMLQDEIN RVNSENKKLT
EMLARVCEKY YALNNLMEEL QSRKSPESVN FQNKQLTGKR KQELDEFVSS PIGLSLGPIE
NITNDKATVS TAYFAAEKSD TSLTVKDGYQ WRKYGQKITR DNPSPRAYFR CSFSPSCLVK
KKVQRSAEDP SFLVATYEGT HNHTGPHASV SRTVKLDLVQ GGLEPVEEKK ERGTIQEVLV
QQMASSLTKD PKFTAALATA ISGRLIEHSR T
