ID   CANA_CANGL              Reviewed;         445 AA.
AC   P10562;
DT   01-JUL-1989, integrated into UniProtKB/Swiss-Prot.
DT   01-JUL-1989, sequence version 1.
DT   25-MAY-2022, entry version 81.
DE   RecName: Full=Canavalin;
DE   Flags: Precursor;
OS   Canavalia gladiata (Sword bean) (Dolichos gladiatus).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; fabids; Fabales; Fabaceae; Papilionoideae; 50 kb inversion clade;
OC   NPAAA clade; indigoferoid/millettioid clade; Phaseoleae; Canavalia.
OX   NCBI_TaxID=3824;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA], AND PROTEIN SEQUENCE OF 27-40.
RC   TISSUE=Seed;
RX   PubMed=3338449; DOI=10.1111/j.1432-1033.1988.tb13730.x;
RA   Yamauchi D., Nakamura K., Asahi T., Minamikawa T.;
RT   "cDNAs for canavalin and concanavalin A from Canavalia gladiata seeds.
RT   Nucleotide sequence of cDNA for canavalin and RNA blot analysis of
RT   canavalin and concanavalin A mRNAs in developing seeds.";
RL   Eur. J. Biochem. 170:515-520(1988).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   TISSUE=Seed;
RX   PubMed=2740227; DOI=10.1093/nar/17.11.4381;
RA   Takei Y., Yamauchi D., Minamikawa T.;
RT   "Nucleotide sequence of the canavalin gene from Canavalia gladiata seeds.";
RL   Nucleic Acids Res. 17:4381-4381(1989).
CC   -!- FUNCTION: Seed storage protein.
CC   -!- SUBUNIT: Homotrimer.
CC   -!- SIMILARITY: Belongs to the 7S seed storage protein family.
CC       {ECO:0000305}.
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DR   EMBL; X06733; CAA29910.1; -; mRNA.
DR   EMBL; X15076; CAA33172.1; -; Genomic_DNA.
DR   PIR; S00281; S00281.
DR   AlphaFoldDB; P10562; -.
DR   SMR; P10562; -.
DR   GO; GO:0045735; F:nutrient reservoir activity; IEA:UniProtKB-KW.
DR   Gene3D; 2.60.120.10; -; 2.
DR   InterPro; IPR006045; Cupin_1.
DR   InterPro; IPR014710; RmlC-like_jellyroll.
DR   InterPro; IPR011051; RmlC_Cupin_sf.
DR   Pfam; PF00190; Cupin_1; 2.
DR   SMART; SM00835; Cupin_1; 2.
DR   SUPFAM; SSF51182; SSF51182; 2.
PE   1: Evidence at protein level;
KW   Direct protein sequencing; Seed storage protein; Signal; Storage protein.
FT   SIGNAL          1..26
FT                   /evidence="ECO:0000269|PubMed:3338449"
FT   CHAIN           27..445
FT                   /note="Canavalin"
FT                   /id="PRO_0000032175"
FT   DOMAIN          49..207
FT                   /note="Cupin type-1 1"
FT                   /evidence="ECO:0000255"
FT   DOMAIN          249..407
FT                   /note="Cupin type-1 2"
FT                   /evidence="ECO:0000255"
FT   CONFLICT        161
FT                   /note="N -> K (in Ref. 2; CAA33172)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   445 AA;  50290 MW;  739B59CC2292EA80 CRC64;
     MAFSARFPLW LLLGVVLLAS VSASFAHSGH SGGEAEDESE ESRAQNNPYL FRSNKFLTLF
     KNQHGSLRLL QRFNEDTEKL ENLRDYRVLE YCSKPNTLLL PHHSDSDLLV LVLEGQAILV
     LVNPDGRDTY KLDQGDAIKI QAGTPFYLIN PDNNQNLRIL NFAITFRRPG TVEDFFLSST
     KRLPSYLSAF SKNFLEASYD SPYDEIEQTL LQEEQEGVIV KMPKDQIQEI SKHAQSSSRK
     TLSSQDKPFN LRSRDPIYSN NYGKLYEITP EKNSQLRDLD ILLNCLQMNE GALFVPHYNS
     RATVILVANE GRAEVELVGL EQQQQQGLES MQLRRYAATL SEGDILVIPS SFPVALKAAS
     DLNMVGIGVN AENNERNFLA GNKENVIRQI PRQVSDLTFP GSGEEVEELL ENQKESYFVD
     GQPRHIDAGG KARRAHLPNL FRTFY