ID   WSCD2_ARTBC             Reviewed;         720 AA.
AC   D4AUF4;
DT   11-NOV-2015, integrated into UniProtKB/Swiss-Prot.
DT   18-MAY-2010, sequence version 1.
DT   25-MAY-2022, entry version 37.
DE   RecName: Full=WSC domain-containing protein ARB_07870 {ECO:0000305};
DE   Flags: Precursor;
GN   ORFNames=ARB_07870;
OS   Arthroderma benhamiae (strain ATCC MYA-4681 / CBS 112371) (Trichophyton
OS   mentagrophytes).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Onygenales; Arthrodermataceae; Trichophyton.
OX   NCBI_TaxID=663331;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA], IDENTIFICATION BY MASS
RP   SPECTROMETRY, AND SUBCELLULAR LOCATION.
RC   STRAIN=ATCC MYA-4681 / CBS 112371;
RX   PubMed=21247460; DOI=10.1186/gb-2011-12-1-r7;
RA   Burmester A., Shelest E., Gloeckner G., Heddergott C., Schindler S.,
RA   Staib P., Heidel A., Felder M., Petzold A., Szafranski K., Feuermann M.,
RA   Pedruzzi I., Priebe S., Groth M., Winkler R., Li W., Kniemeyer O.,
RA   Schroeckh V., Hertweck C., Hube B., White T.C., Platzer M., Guthke R.,
RA   Heitman J., Woestemeyer J., Zipfel P.F., Monod M., Brakhage A.A.;
RT   "Comparative and functional genomics provide insights into the
RT   pathogenicity of dermatophytic fungi.";
RL   Genome Biol. 12:R7.1-R7.16(2011).
RN   [2]
RP   IDENTIFICATION BY MASS SPECTROMETRY, AND SUBCELLULAR LOCATION.
RX   PubMed=21919205; DOI=10.1002/pmic.201100234;
RA   Sriranganadane D., Waridel P., Salamin K., Feuermann M., Mignon B.,
RA   Staib P., Neuhaus J.M., Quadroni M., Monod M.;
RT   "Identification of novel secreted proteases during extracellular
RT   proteolysis by dermatophytes at acidic pH.";
RL   Proteomics 11:4422-4433(2011).
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:21247460,
CC       ECO:0000269|PubMed:21919205}.
CC   -!- SIMILARITY: Belongs to the WSCD family. {ECO:0000305}.
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DR   EMBL; ABSU01000011; EFE33119.1; -; Genomic_DNA.
DR   RefSeq; XP_003013759.1; XM_003013713.1.
DR   AlphaFoldDB; D4AUF4; -.
DR   STRING; 663331.D4AUF4; -.
DR   EnsemblFungi; EFE33119; EFE33119; ARB_07870.
DR   GeneID; 9526949; -.
DR   KEGG; abe:ARB_07870; -.
DR   eggNOG; KOG4157; Eukaryota.
DR   HOGENOM; CLU_004824_1_0_1; -.
DR   OMA; RVGFHDM; -.
DR   Proteomes; UP000008866; Unassembled WGS sequence.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0020037; F:heme binding; IEA:InterPro.
DR   GO; GO:0004601; F:peroxidase activity; IEA:InterPro.
DR   GO; GO:0006979; P:response to oxidative stress; IEA:InterPro.
DR   InterPro; IPR002016; Haem_peroxidase.
DR   InterPro; IPR010255; Haem_peroxidase_sf.
DR   InterPro; IPR002889; WSC_carb-bd.
DR   Pfam; PF00141; peroxidase; 1.
DR   Pfam; PF01822; WSC; 2.
DR   PRINTS; PR00458; PEROXIDASE.
DR   SMART; SM00321; WSC; 2.
DR   SUPFAM; SSF48113; SSF48113; 1.
DR   PROSITE; PS50873; PEROXIDASE_4; 1.
DR   PROSITE; PS51212; WSC; 2.
PE   1: Evidence at protein level;
KW   Glycoprotein; Reference proteome; Repeat; Secreted; Signal.
FT   SIGNAL          1..24
FT                   /evidence="ECO:0000255"
FT   CHAIN           25..720
FT                   /note="WSC domain-containing protein ARB_07870"
FT                   /id="PRO_5003053665"
FT   DOMAIN          524..615
FT                   /note="WSC 1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00558"
FT   DOMAIN          627..718
FT                   /note="WSC 2"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00558"
FT   CARBOHYD        4
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
FT   CARBOHYD        108
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
FT   CARBOHYD        181
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
FT   CARBOHYD        264
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
FT   CARBOHYD        296
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
FT   CARBOHYD        318
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
FT   CARBOHYD        474
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
FT   CARBOHYD        549
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
FT   CARBOHYD        581
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
FT   CARBOHYD        629
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
FT   CARBOHYD        640
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
FT   CARBOHYD        663
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
FT   CARBOHYD        701
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
SQ   SEQUENCE   720 AA;  76986 MW;  7091FF4D460E4875 CRC64;
     MLINLSAVWA AFALSGVLAP PTWPASIDEL EDLMFLNTGY HARGFSAGVT PCSFSQQGPS
     RVASAEWVRT AFHDMATGNS FTGVGGLDAS IVFELGGKGG ENIGAGFNTT LETYTPFFST
     RSSMADLIAL GVYTAVRSCG GPVVQVRTGR IDATARGPIG VPQPENSQGT FINQFTRMGF
     NVSDMIAVTA CGHTMGGVHA SNFPQIVVPG SAPNDFQLFD STVSFDEKVA VDFVGGVAGN
     PLTSTTAKRS QRDADMKVFT ADRNVTIKAL ADQVTFRSTC ARVLQKMIEV VPSGVNLTAP
     IAPYEVKPGR LQLSLASNGS TIAFTGEIRV RTTSRPVTSI SKVELVYKDR TGGSSCGSCI
     ITTEYKGTAE GFDDSFAFYG FEARFPVETA ISKFNVRVVL NTGETVVYNN NDEEDDNRLI
     ISQKVRKNAN TGSVKLSVTT KTPRSCCVTP ALTTQSVPMS PQTTVGPYTL YAGNLTLAAA
     YRSNAKFDVS LTSGGAVISD SFKNTADLSS TCAPFGSNDP TMPDYTFDGC YTDTPESRAL
     TSAAFVKENM TIAACSSLCK GYQFFGLEYG TECYCGDTRS NSSMQAPKSE CNQPCGGDSS
     ETCGAGYRIA IYKDDKWVPI TSPQIPGYNY TGCYSDSPSN RTLSGSFTYN EKMTVELCAS
     FCNGTKYFGV EYFSECYCGA NMFPGSTIQP ESDCGFFFSA NKTQHCGGSN RINIYTKLDM