ID   WSDU1_DANRE             Reviewed;         487 AA.
AC   A0AUS0;
DT   20-FEB-2007, integrated into UniProtKB/Swiss-Prot.
DT   28-NOV-2006, sequence version 1.
DT   03-AUG-2022, entry version 100.
DE   RecName: Full=WD repeat, SAM and U-box domain-containing protein 1;
GN   Name=wdsub1; ORFNames=zgc:154085;
OS   Danio rerio (Zebrafish) (Brachydanio rerio).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC   Danionidae; Danioninae; Danio.
OX   NCBI_TaxID=7955;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Ovary;
RG   NIH - Zebrafish Gene Collection (ZGC) project;
RL   Submitted (OCT-2006) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; BC124806; AAI24807.1; -; mRNA.
DR   RefSeq; NP_001071237.1; NM_001077769.1.
DR   RefSeq; XP_017212008.1; XM_017356519.1.
DR   AlphaFoldDB; A0AUS0; -.
DR   SMR; A0AUS0; -.
DR   STRING; 7955.ENSDARP00000105402; -.
DR   PaxDb; A0AUS0; -.
DR   Ensembl; ENSDART00000128024; ENSDARP00000106094; ENSDARG00000090418.
DR   GeneID; 777721; -.
DR   KEGG; dre:777721; -.
DR   CTD; 151525; -.
DR   ZFIN; ZDB-GENE-061110-97; wdsub1.
DR   eggNOG; KOG4155; Eukaryota.
DR   GeneTree; ENSGT00940000157230; -.
DR   InParanoid; A0AUS0; -.
DR   OMA; AWLCAQD; -.
DR   OrthoDB; 957291at2759; -.
DR   PhylomeDB; A0AUS0; -.
DR   PRO; PR:A0AUS0; -.
DR   Proteomes; UP000000437; Genome assembly.
DR   Proteomes; UP000814640; Chromosome 6.
DR   Bgee; ENSDARG00000090418; Expressed in cardiac ventricle and 20 other tissues.
DR   ExpressionAtlas; A0AUS0; baseline.
DR   GO; GO:0004842; F:ubiquitin-protein transferase activity; IEA:InterPro.
DR   Gene3D; 1.10.150.50; -; 1.
DR   Gene3D; 2.130.10.10; -; 3.
DR   Gene3D; 3.30.40.10; -; 1.
DR   InterPro; IPR020472; G-protein_beta_WD-40_rep.
DR   InterPro; IPR001660; SAM.
DR   InterPro; IPR013761; SAM/pointed_sf.
DR   InterPro; IPR003613; Ubox_domain.
DR   InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR   InterPro; IPR001680; WD40_repeat.
DR   InterPro; IPR019775; WD40_repeat_CS.
DR   InterPro; IPR036322; WD40_repeat_dom_sf.
DR   InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR   Pfam; PF07647; SAM_2; 1.
DR   Pfam; PF04564; U-box; 1.
DR   Pfam; PF00400; WD40; 6.
DR   PRINTS; PR00320; GPROTEINBRPT.
DR   SMART; SM00454; SAM; 1.
DR   SMART; SM00504; Ubox; 1.
DR   SMART; SM00320; WD40; 7.
DR   SUPFAM; SSF47769; SSF47769; 1.
DR   SUPFAM; SSF50978; SSF50978; 1.
DR   PROSITE; PS50105; SAM_DOMAIN; 1.
DR   PROSITE; PS51698; U_BOX; 1.
DR   PROSITE; PS00678; WD_REPEATS_1; 1.
DR   PROSITE; PS50082; WD_REPEATS_2; 6.
DR   PROSITE; PS50294; WD_REPEATS_REGION; 1.
PE   2: Evidence at transcript level;
KW   Reference proteome; Repeat; WD repeat.
FT   CHAIN           1..487
FT                   /note="WD repeat, SAM and U-box domain-containing protein
FT                   1"
FT                   /id="PRO_0000278612"
FT   REPEAT          10..47
FT                   /note="WD 1"
FT   REPEAT          52..93
FT                   /note="WD 2"
FT   REPEAT          95..134
FT                   /note="WD 3"
FT   REPEAT          137..176
FT                   /note="WD 4"
FT   REPEAT          179..227
FT                   /note="WD 5"
FT   REPEAT          237..276
FT                   /note="WD 6"
FT   REPEAT          279..318
FT                   /note="WD 7"
FT   DOMAIN          347..411
FT                   /note="SAM"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00184"
FT   DOMAIN          416..487
FT                   /note="U-box"
SQ   SEQUENCE   487 AA;  53125 MW;  96D6EABCBB5F01AA CRC64;
     MVSLICTLQS HRDDVNCVAF SGDLLATCSA DKSICVYSSR DFSELPFSPL SGHGYGVHCC
     CFSACGQYLA SCSTDATTMV WSMDTGEIEA VLEHPGRSPV RVCAFSPDSS HLVSGGSDGS
     IALWDFTSRT LRRTGVVNDT SIVACSFTPC GQMFITGSTY GDLRLWDLNM NHLHAEKNAH
     DLGVSCAQFA PKMMKGTDGC VQFRLASCGQ DSLLKIWIVS LLPSAGIKMQ LAHTLTGQSA
     PVLSCAYSPD GQMLVSGSVD KTVTVYQADE GVLLYTLHQH DRYVTACAFS PTAPLIATGS
     MDKSVNIWRM EEGSSAQGKS LPDEKAAFSN TEGRKACGHS RLMVSEWSEE EVLAWLREEG
     LEAVTDAFKS NNIDGEELLS LSKETLSSDL HIESLGLRSK VMKKIEELKM VPVYNGTPDE
     FLCPITREIM KDPVIAADGY SYEREAIEAW ISTKNRTSPM TNLPLQTTLL TPNRTLKMAI
     FRWSTSQ