ID   WSDU1_RAT               Reviewed;         476 AA.
AC   Q5FVN8;
DT   20-FEB-2007, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2005, sequence version 1.
DT   03-AUG-2022, entry version 110.
DE   RecName: Full=WD repeat, SAM and U-box domain-containing protein 1;
GN   Name=Wdsub1;
OS   Rattus norvegicus (Rat).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Rattus.
OX   NCBI_TaxID=10116;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Thymus;
RX   PubMed=15489334; DOI=10.1101/gr.2596504;
RG   The MGC Project Team;
RT   "The status, quality, and expansion of the NIH full-length cDNA project:
RT   the Mammalian Gene Collection (MGC).";
RL   Genome Res. 14:2121-2127(2004).
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; BC089856; AAH89856.1; -; mRNA.
DR   RefSeq; NP_001014201.1; NM_001014179.1.
DR   RefSeq; XP_006234273.1; XM_006234211.3.
DR   AlphaFoldDB; Q5FVN8; -.
DR   SMR; Q5FVN8; -.
DR   STRING; 10116.ENSRNOP00000008168; -.
DR   PhosphoSitePlus; Q5FVN8; -.
DR   PaxDb; Q5FVN8; -.
DR   PRIDE; Q5FVN8; -.
DR   GeneID; 362137; -.
DR   KEGG; rno:362137; -.
DR   UCSC; RGD:1359296; rat.
DR   CTD; 151525; -.
DR   RGD; 1359296; Wdsub1.
DR   eggNOG; KOG4155; Eukaryota.
DR   HOGENOM; CLU_038099_0_0_1; -.
DR   InParanoid; Q5FVN8; -.
DR   OrthoDB; 957291at2759; -.
DR   PhylomeDB; Q5FVN8; -.
DR   TreeFam; TF328991; -.
DR   PRO; PR:Q5FVN8; -.
DR   Proteomes; UP000002494; Unplaced.
DR   Genevisible; Q5FVN8; RN.
DR   GO; GO:0110165; C:cellular anatomical entity; IEA:UniProt.
DR   GO; GO:0004842; F:ubiquitin-protein transferase activity; IEA:InterPro.
DR   Gene3D; 1.10.150.50; -; 1.
DR   Gene3D; 2.130.10.10; -; 3.
DR   Gene3D; 3.30.40.10; -; 1.
DR   InterPro; IPR020472; G-protein_beta_WD-40_rep.
DR   InterPro; IPR001660; SAM.
DR   InterPro; IPR013761; SAM/pointed_sf.
DR   InterPro; IPR003613; Ubox_domain.
DR   InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR   InterPro; IPR001680; WD40_repeat.
DR   InterPro; IPR036322; WD40_repeat_dom_sf.
DR   InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR   Pfam; PF07647; SAM_2; 1.
DR   Pfam; PF04564; U-box; 1.
DR   Pfam; PF00400; WD40; 7.
DR   PRINTS; PR00320; GPROTEINBRPT.
DR   SMART; SM00454; SAM; 1.
DR   SMART; SM00504; Ubox; 1.
DR   SMART; SM00320; WD40; 7.
DR   SUPFAM; SSF47769; SSF47769; 1.
DR   SUPFAM; SSF50978; SSF50978; 1.
DR   PROSITE; PS50105; SAM_DOMAIN; 1.
DR   PROSITE; PS51698; U_BOX; 1.
DR   PROSITE; PS00678; WD_REPEATS_1; 1.
DR   PROSITE; PS50082; WD_REPEATS_2; 5.
DR   PROSITE; PS50294; WD_REPEATS_REGION; 1.
PE   2: Evidence at transcript level;
KW   Phosphoprotein; Reference proteome; Repeat; WD repeat.
FT   CHAIN           1..476
FT                   /note="WD repeat, SAM and U-box domain-containing protein
FT                   1"
FT                   /id="PRO_0000278610"
FT   REPEAT          10..47
FT                   /note="WD 1"
FT   REPEAT          52..91
FT                   /note="WD 2"
FT   REPEAT          95..134
FT                   /note="WD 3"
FT   REPEAT          137..176
FT                   /note="WD 4"
FT   REPEAT          178..228
FT                   /note="WD 5"
FT   REPEAT          237..276
FT                   /note="WD 6"
FT   REPEAT          279..318
FT                   /note="WD 7"
FT   DOMAIN          332..396
FT                   /note="SAM"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00184"
FT   DOMAIN          403..476
FT                   /note="U-box"
FT   MOD_RES         458
FT                   /note="Phosphothreonine"
FT                   /evidence="ECO:0000250|UniProtKB:Q8N9V3"
SQ   SEQUENCE   476 AA;  52244 MW;  4EB0BB00F19C132A CRC64;
     MVKLIHTLAD HGDDVSCCAF SSTLLATCSL DKTIRLYSLS DFAELPHSPL KFHTYAVHCC
     SFSPSGHVLA SCSTDGTTVL WSAHSGHTLT VLEQPGGSPV RVCCFSPDST YLASGAADGS
     VVLWNAHSYK LYRCGSVKDS SLVACAFSPD GGLLVTGSSG GDLTVWDDRM RCLHSEKAHD
     LGITCCSFSS QPLSGGEHGL QLYRLASCGQ DCEIKLWVVS FTRVLGFELK YRSTLSGHCA
     PVLACAFSHD GQMLASGSVD KSVIIYDIGT QSVLHTLTQH TRYVTTCAFA PNTLLLATGS
     MDKTVNIWQF DLETPCQAGS VSDQLKHFIE DWSEEDVSKW LRAQGLEDLV DIFRTNNIDG
     KELLHLTKES LAGDMKIESL GLRSKVLRSI DELRTRMESL SSGIPDEFIC PITRELMKDP
     VIASDGYSYE REAMESWIHK KKRTSPMTNL ALPSLVLTPN RTLKMAINRW LETHQK