WTF1_ARATH
ID WTF1_ARATH Reviewed; 528 AA.
AC A0MFS5; O04624;
DT 25-OCT-2017, integrated into UniProtKB/Swiss-Prot.
DT 12-DEC-2006, sequence version 1.
DT 25-MAY-2022, entry version 90.
DE RecName: Full=Protein WHAT'S THIS FACTOR 1 homolog, chloroplastic {ECO:0000305};
DE Flags: Precursor;
GN OrderedLocusNames=At4g01037 {ECO:0000312|Araport:AT4G01037};
GN ORFNames=A_IG002N01.30 {ECO:0000312|EMBL:AAB61038.1};
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10617198; DOI=10.1038/47134;
RA Mayer K.F.X., Schueller C., Wambutt R., Murphy G., Volckaert G., Pohl T.,
RA Duesterhoeft A., Stiekema W., Entian K.-D., Terryn N., Harris B.,
RA Ansorge W., Brandt P., Grivell L.A., Rieger M., Weichselgartner M.,
RA de Simone V., Obermaier B., Mache R., Mueller M., Kreis M., Delseny M.,
RA Puigdomenech P., Watson M., Schmidtheini T., Reichert B., Portetelle D.,
RA Perez-Alonso M., Boutry M., Bancroft I., Vos P., Hoheisel J.,
RA Zimmermann W., Wedler H., Ridley P., Langham S.-A., McCullagh B.,
RA Bilham L., Robben J., van der Schueren J., Grymonprez B., Chuang Y.-J.,
RA Vandenbussche F., Braeken M., Weltjens I., Voet M., Bastiaens I., Aert R.,
RA Defoor E., Weitzenegger T., Bothe G., Ramsperger U., Hilbert H., Braun M.,
RA Holzer E., Brandt A., Peters S., van Staveren M., Dirkse W., Mooijman P.,
RA Klein Lankhorst R., Rose M., Hauf J., Koetter P., Berneiser S., Hempel S.,
RA Feldpausch M., Lamberth S., Van den Daele H., De Keyser A., Buysshaert C.,
RA Gielen J., Villarroel R., De Clercq R., van Montagu M., Rogers J.,
RA Cronin A., Quail M.A., Bray-Allen S., Clark L., Doggett J., Hall S.,
RA Kay M., Lennard N., McLay K., Mayes R., Pettett A., Rajandream M.A.,
RA Lyne M., Benes V., Rechmann S., Borkova D., Bloecker H., Scharfe M.,
RA Grimm M., Loehnert T.-H., Dose S., de Haan M., Maarse A.C., Schaefer M.,
RA Mueller-Auer S., Gabel C., Fuchs M., Fartmann B., Granderath K., Dauner D.,
RA Herzl A., Neumann S., Argiriou A., Vitale D., Liguori R., Piravandi E.,
RA Massenet O., Quigley F., Clabauld G., Muendlein A., Felber R., Schnabl S.,
RA Hiller R., Schmidt W., Lecharny A., Aubourg S., Chefdor F., Cooke R.,
RA Berger C., Monfort A., Casacuberta E., Gibbons T., Weber N., Vandenbol M.,
RA Bargues M., Terol J., Torres A., Perez-Perez A., Purnelle B., Bent E.,
RA Johnson S., Tacon D., Jesse T., Heijnen L., Schwarz S., Scholler P.,
RA Heber S., Francs P., Bielke C., Frishman D., Haase D., Lemcke K.,
RA Mewes H.-W., Stocker S., Zaccaria P., Bevan M., Wilson R.K.,
RA de la Bastide M., Habermann K., Parnell L., Dedhia N., Gnoj L., Schutz K.,
RA Huang E., Spiegel L., Sekhon M., Murray J., Sheet P., Cordes M.,
RA Abu-Threideh J., Stoneking T., Kalicki J., Graves T., Harmon G.,
RA Edwards J., Latreille P., Courtney L., Cloud J., Abbott A., Scott K.,
RA Johnson D., Minx P., Bentley D., Fulton B., Miller N., Greco T., Kemp K.,
RA Kramer J., Fulton L., Mardis E., Dante M., Pepin K., Hillier L.W.,
RA Nelson J., Spieth J., Ryan E., Andrews S., Geisel C., Layman D., Du H.,
RA Ali J., Berghoff A., Jones K., Drone K., Cotton M., Joshu C., Antonoiu B.,
RA Zidanic M., Strong C., Sun H., Lamar B., Yordan C., Ma P., Zhong J.,
RA Preston R., Vil D., Shekher M., Matero A., Shah R., Swaby I.K.,
RA O'Shaughnessy A., Rodriguez M., Hoffman J., Till S., Granat S., Shohdy N.,
RA Hasegawa A., Hameed A., Lodhi M., Johnson A., Chen E., Marra M.A.,
RA Martienssen R., McCombie W.R.;
RT "Sequence and analysis of chromosome 4 of the plant Arabidopsis thaliana.";
RL Nature 402:769-777(1999).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=17147637; DOI=10.1111/j.1467-7652.2006.00183.x;
RA Underwood B.A., Vanderhaeghen R., Whitford R., Town C.D., Hilson P.;
RT "Simultaneous high-throughput recombinational cloning of open reading
RT frames in closed and open configurations.";
RL Plant Biotechnol. J. 4:317-324(2006).
CC -!- FUNCTION: RNA-binding protein involved in group II intron splicing.
CC Binds specific group II introns and promotes their splicing. Functions
CC in the context of a heterodimer with the ribonuclease III domain-
CC containing protein RNC1. {ECO:0000250|UniProtKB:B6TTV8}.
CC -!- SUBCELLULAR LOCATION: Plastid, chloroplast {ECO:0000255}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAB61038.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR EMBL; AF007269; AAB61038.1; ALT_SEQ; Genomic_DNA.
DR EMBL; CP002687; AEE81971.1; -; Genomic_DNA.
DR EMBL; DQ653402; ABK28304.1; -; Genomic_DNA.
DR PIR; T01734; T01734.
DR RefSeq; NP_001118908.1; NM_001125436.2.
DR AlphaFoldDB; A0MFS5; -.
DR STRING; 3702.AT4G01037.1; -.
DR PaxDb; A0MFS5; -.
DR PRIDE; A0MFS5; -.
DR ProteomicsDB; 242450; -.
DR EnsemblPlants; AT4G01037.1; AT4G01037.1; AT4G01037.
DR GeneID; 6240517; -.
DR Gramene; AT4G01037.1; AT4G01037.1; AT4G01037.
DR KEGG; ath:AT4G01037; -.
DR Araport; AT4G01037; -.
DR TAIR; locus:4515103321; AT4G01037.
DR eggNOG; ENOG502QRW0; Eukaryota.
DR HOGENOM; CLU_024287_4_1_1; -.
DR InParanoid; A0MFS5; -.
DR OMA; SPYSDFT; -.
DR OrthoDB; 710613at2759; -.
DR PhylomeDB; A0MFS5; -.
DR PRO; PR:A0MFS5; -.
DR Proteomes; UP000006548; Chromosome 4.
DR ExpressionAtlas; A0MFS5; baseline and differential.
DR GO; GO:0009507; C:chloroplast; IDA:TAIR.
DR GO; GO:0003729; F:mRNA binding; IDA:TAIR.
DR GO; GO:0003723; F:RNA binding; IDA:TAIR.
DR GO; GO:0000373; P:Group II intron splicing; IMP:TAIR.
DR GO; GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
DR GO; GO:0015979; P:photosynthesis; IMP:TAIR.
DR InterPro; IPR021099; PORR_domain.
DR InterPro; IPR045040; PORR_fam.
DR InterPro; IPR040293; WTF1-like.
DR PANTHER; PTHR31476; PTHR31476; 1.
DR PANTHER; PTHR31476:SF4; PTHR31476:SF4; 1.
DR Pfam; PF11955; PORR; 1.
PE 3: Inferred from homology;
KW Chloroplast; mRNA processing; mRNA splicing; Plastid; Reference proteome;
KW RNA-binding; Transit peptide.
FT TRANSIT 1..73
FT /note="Chloroplast"
FT /evidence="ECO:0000255"
FT CHAIN 74..528
FT /note="Protein WHAT'S THIS FACTOR 1 homolog, chloroplastic"
FT /id="PRO_0000441883"
FT DOMAIN 80..408
FT /note="PORR"
FT /evidence="ECO:0000255"
FT REGION 410..528
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 428..492
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 528 AA; 61233 MW; 4EA3549D283DA22B CRC64;
MEPKLLLSAH KPLFVSCNSP FNEKTKLSVK SGLPMSTIRA ARSQFMGEGL ILGNKYGFWS
TSRKTRVVVE PVRAAVKRRK ELTFDSVVQR DKKLKLVLNI RKILVSQPDR MMSLRGLGKY
RRDLGLKKRR RFIALLRKYP GVFEIVEEGA YSLRFKMTSE AERLYLDEMR IRNELEDVLV
VKLRKLVMMS IDKRILLEKI SHLKTDLGLP LEFRDTICQR YPQYFRVVPT PRGPALELTH
WDPELAVSAA ELSEDDNRTR ESEERNLIID RPPKFNRVKL PRGLNLSKSE TRKISQFRDM
QYISPYKDFS HLRSGTLEKE KHACGVIHEL LSLTTEKRTL VDHLTHFREE FRFSQQLRGM
LIRHPDLFYV SLKGERDSVF LREAYRNSEL IDKDPLTLVK EKMRALVSVP RFPRRGGPRK
DEEGREVEID GSDADGEEEE EESDAEEWSD VDGYLEGEDG GNDDDGDWTD DEGEEDVPPN
FDDDDEDEEE DSVKIGLSPS SRKSSSPRKK EEKVLTPVFP DGTPREKW
