ID   WTF7_SCHKA              Reviewed;         218 AA.
AC   A0A482APM8;
DT   07-APR-2021, integrated into UniProtKB/Swiss-Prot.
DT   05-JUN-2019, sequence version 1.
DT   25-MAY-2022, entry version 10.
DE   RecName: Full=Wtf element wtf7 {ECO:0000303|PubMed:32032353};
GN   Name=wtf7 {ECO:0000312|EMBL:QBL54498.1};
OS   Schizosaccharomyces kambucha (Fission yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC   Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC   Schizosaccharomyces.
OX   NCBI_TaxID=204045 {ECO:0000312|EMBL:QBL54498.1};
RN   [1] {ECO:0000312|EMBL:QBL54498.1}
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA], AND SUBCELLULAR LOCATION.
RX   PubMed=32032353; DOI=10.1371/journal.pgen.1008350;
RA   Bravo Nunez M.A., Sabbarini I.M., Eickbush M.T., Liang Y., Lange J.J.,
RA   Kent A.M., Zanders S.E.;
RT   "Dramatically diverse Schizosaccharomyces pombe wtf meiotic drivers all
RT   display high gamete-killing efficiency.";
RL   PLoS Genet. 16:e1008350-e1008350(2020).
CC   -!- FUNCTION: May act in meiotic drive. {ECO:0000250|UniProtKB:A0A218N034}.
CC   -!- SUBCELLULAR LOCATION: Spore membrane {ECO:0000255,
CC       ECO:0000269|PubMed:32032353}; Multi-pass membrane protein
CC       {ECO:0000255}.
CC   -!- SIMILARITY: Belongs to the WTF family. {ECO:0000305}.
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DR   EMBL; MH837433; QBL54498.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A482APM8; -.
DR   GO; GO:0005737; C:cytoplasm; IDA:UniProtKB.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0110134; P:meiotic drive; IEA:InterPro.
DR   InterPro; IPR004982; WTF.
DR   Pfam; PF03303; WTF; 1.
PE   3: Inferred from homology;
KW   Membrane; Transmembrane; Transmembrane helix.
FT   CHAIN           1..218
FT                   /note="Wtf element wtf7"
FT                   /id="PRO_0000452257"
FT   TRANSMEM        122..142
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        152..172
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        191..211
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   REGION          1..23
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   218 AA;  24907 MW;  CD21897DE76A714D CRC64;
     MLKMSGSYAP VEDSADELSV HSGNDNEIDL EKGLLPKCNT GNGGTTPCSE PPHYDSDAVV
     EMDMYENNIY MQTFKLRPFP KSGVTNFSNV VFQMKTYENN RHMQTFRLRP FAKNGVTNGV
     KLAQVLFLLL PFNFIFIACL FFRKASFTDF SLMGWILFGI WCLTCFLSSF ILYAYHESWT
     KFARERPDDF AGILILLLFP GIVTMIVFYG IYMNSIYG