WTR15_ARATH
ID WTR15_ARATH Reviewed; 394 AA.
AC F4IJ08; O22204;
DT 06-MAR-2013, integrated into UniProtKB/Swiss-Prot.
DT 28-JUN-2011, sequence version 1.
DT 03-AUG-2022, entry version 57.
DE RecName: Full=WAT1-related protein At2g40900;
GN OrderedLocusNames=At2g40900; ORFNames=T20B5.10;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10617197; DOI=10.1038/45471;
RA Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D.,
RA Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V.,
RA Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H.L., Moffat K.S.,
RA Cronin L.A., Shen M., Pai G., Van Aken S., Umayam L., Tallon L.J.,
RA Gill J.E., Adams M.D., Carrera A.J., Creasy T.H., Goodman H.M.,
RA Somerville C.R., Copenhaver G.P., Preuss D., Nierman W.C., White O.,
RA Eisen J.A., Salzberg S.L., Fraser C.M., Venter J.C.;
RT "Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana.";
RL Nature 402:761-768(1999).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RA Totoki Y., Seki M., Ishida J., Nakajima M., Enju A., Kamiya A.,
RA Narusaka M., Shin-i T., Nakagawa M., Sakamoto N., Oishi K., Kohara Y.,
RA Kobayashi M., Toyoda A., Sakaki Y., Sakurai T., Iida K., Akiyama K.,
RA Satou M., Toyoda T., Konagaya A., Carninci P., Kawai J., Hayashizaki Y.,
RA Shinozaki K.;
RT "Large-scale analysis of RIKEN Arabidopsis full-length (RAFL) cDNAs.";
RL Submitted (JUL-2006) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000250}; Multi-pass membrane
CC protein {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the drug/metabolite transporter (DMT)
CC superfamily. Plant drug/metabolite exporter (P-DME) (TC 2.A.7.4)
CC family. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAB86450.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR EMBL; AC002409; AAB86450.1; ALT_SEQ; Genomic_DNA.
DR EMBL; CP002685; AEC09894.1; -; Genomic_DNA.
DR EMBL; AK226262; -; NOT_ANNOTATED_CDS; mRNA.
DR PIR; T00754; T00754.
DR RefSeq; NP_181622.2; NM_129653.5.
DR AlphaFoldDB; F4IJ08; -.
DR SMR; F4IJ08; -.
DR BioGRID; 4024; 3.
DR IntAct; F4IJ08; 3.
DR STRING; 3702.AT2G40900.1; -.
DR PaxDb; F4IJ08; -.
DR PRIDE; F4IJ08; -.
DR ProteomicsDB; 243025; -.
DR EnsemblPlants; AT2G40900.1; AT2G40900.1; AT2G40900.
DR GeneID; 818687; -.
DR Gramene; AT2G40900.1; AT2G40900.1; AT2G40900.
DR KEGG; ath:AT2G40900; -.
DR Araport; AT2G40900; -.
DR TAIR; locus:2058460; AT2G40900.
DR eggNOG; ENOG502QRHH; Eukaryota.
DR HOGENOM; CLU_025359_1_1_1; -.
DR InParanoid; F4IJ08; -.
DR OMA; KARCQVK; -.
DR OrthoDB; 718138at2759; -.
DR PRO; PR:F4IJ08; -.
DR Proteomes; UP000006548; Chromosome 2.
DR ExpressionAtlas; F4IJ08; baseline and differential.
DR Genevisible; F4IJ08; AT.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IDA:TAIR.
DR GO; GO:0015186; F:L-glutamine transmembrane transporter activity; IDA:TAIR.
DR GO; GO:0048316; P:seed development; IMP:TAIR.
DR InterPro; IPR000620; EamA_dom.
DR InterPro; IPR030184; WAT1-related.
DR PANTHER; PTHR31218; PTHR31218; 1.
DR Pfam; PF00892; EamA; 2.
PE 2: Evidence at transcript level;
KW Membrane; Reference proteome; Repeat; Transmembrane; Transmembrane helix.
FT CHAIN 1..394
FT /note="WAT1-related protein At2g40900"
FT /id="PRO_0000421323"
FT TRANSMEM 13..33
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 40..60
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 67..87
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 102..122
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 142..162
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 180..200
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 209..229
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 245..265
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 273..293
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 298..318
FT /note="Helical"
FT /evidence="ECO:0000255"
FT DOMAIN 22..147
FT /note="EamA 1"
FT DOMAIN 189..317
FT /note="EamA 2"
SQ SEQUENCE 394 AA; 43049 MW; F861A95516907113 CRC64;
MGLRMSESAK PYFAMVCLQF GYAGMNLVTK TVLDRGMSHY VLVAYRNAFA TAAIAPFALL
SERKVRSKMT FPIFMRIFLL ALLGPVIDQN LYYIGLKLTS PTFSSAVSNI VPAITIILAT
LFRMEKVEMR KVRCLVKVMG TLVTVVGSIL MIFYKGPFIN FFRSHLTAAS SPPTADYLKA
AVFLLLASLS WASFFVLQAA TLKKYSAHLS MSTMVCFMGT LQSLALAFVM EHNPSALNIG
FDMNLLASAY AGIMSSSIAY YVQGLMMQRK GPVFVTAFNP LIVVIVSIMS FFVLGQGIYL
GGVIGVVVLM VGVYAVLWGK HVDDDGEETR HEDNVVAVKC CSGNNGLTIM PKIDEADEED
VETGKATSEK ESSVPEVVVV VFCSENVHSV SRPN
