ID   WTR19_ARATH             Reviewed;         215 AA.
AC   F4IXT6; Q9LRS9;
DT   06-MAR-2013, integrated into UniProtKB/Swiss-Prot.
DT   28-JUN-2011, sequence version 1.
DT   25-MAY-2022, entry version 56.
DE   RecName: Full=WAT1-related protein At3g28060;
GN   OrderedLocusNames=At3g28060; ORFNames=MMG15.10;
OS   Arabidopsis thaliana (Mouse-ear cress).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX   NCBI_TaxID=3702;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=10907853; DOI=10.1093/dnares/7.3.217;
RA   Kaneko T., Katoh T., Sato S., Nakamura Y., Asamizu E., Tabata S.;
RT   "Structural analysis of Arabidopsis thaliana chromosome 3. II. Sequence
RT   features of the 4,251,695 bp regions covered by 90 P1, TAC and BAC
RT   clones.";
RL   DNA Res. 7:217-221(2000).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Columbia;
RX   PubMed=27862469; DOI=10.1111/tpj.13415;
RA   Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA   Town C.D.;
RT   "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT   genome.";
RL   Plant J. 89:789-804(2017).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000250}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the drug/metabolite transporter (DMT)
CC       superfamily. Plant drug/metabolite exporter (P-DME) (TC 2.A.7.4)
CC       family. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=BAB01128.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AB028616; BAB01128.1; ALT_SEQ; Genomic_DNA.
DR   EMBL; CP002686; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   AlphaFoldDB; F4IXT6; -.
DR   PaxDb; F4IXT6; -.
DR   Araport; AT3G28060; -.
DR   TAIR; locus:2091373; AT3G28060.
DR   eggNOG; ENOG502QRQK; Eukaryota.
DR   HOGENOM; CLU_1284873_0_0_1; -.
DR   InParanoid; F4IXT6; -.
DR   PRO; PR:F4IXT6; -.
DR   Proteomes; UP000006548; Chromosome 3.
DR   ExpressionAtlas; F4IXT6; baseline and differential.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR   InterPro; IPR000620; EamA_dom.
DR   InterPro; IPR030184; WAT1-related.
DR   PANTHER; PTHR31218; PTHR31218; 1.
DR   Pfam; PF00892; EamA; 1.
PE   3: Inferred from homology;
KW   Membrane; Reference proteome; Transmembrane; Transmembrane helix.
FT   CHAIN           1..215
FT                   /note="WAT1-related protein At3g28060"
FT                   /id="PRO_0000421327"
FT   TRANSMEM        48..68
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        82..102
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        117..137
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        146..166
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        176..196
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   DOMAIN          65..186
FT                   /note="EamA"
SQ   SEQUENCE   215 AA;  23472 MW;  EC6BEC127DC52A50 CRC64;
     MAGRFCQRDG GIMTAMVAVE ILTECSQSSW NNSLHCGVFR HLPRNRPIII GSSGEVFWVE
     YTLIAVAYIV QTHIMREYPS EFALALSHNV CVSISCAFVS LFVEENNPSA WIMRSKIMLI
     CIVATGVVNS TSYVVESWTV RYKGAVFLAM FRPLSIVTAV VLGAIFLGDS LYLGSVIGGT
     LISIGFSVHN SLFHIANGFS ALAKSSVLRH IGMLV