ID   WTR24_ARATH             Reviewed;         364 AA.
AC   Q9LI65;
DT   06-MAR-2013, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-2000, sequence version 1.
DT   03-AUG-2022, entry version 111.
DE   RecName: Full=WAT1-related protein At3g30340;
GN   OrderedLocusNames=At3g30340; ORFNames=T6J22.10;
OS   Arabidopsis thaliana (Mouse-ear cress).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX   NCBI_TaxID=3702;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=10907853; DOI=10.1093/dnares/7.3.217;
RA   Kaneko T., Katoh T., Sato S., Nakamura Y., Asamizu E., Tabata S.;
RT   "Structural analysis of Arabidopsis thaliana chromosome 3. II. Sequence
RT   features of the 4,251,695 bp regions covered by 90 P1, TAC and BAC
RT   clones.";
RL   DNA Res. 7:217-221(2000).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Columbia;
RX   PubMed=27862469; DOI=10.1111/tpj.13415;
RA   Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA   Town C.D.;
RT   "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT   genome.";
RL   Plant J. 89:789-804(2017).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=11910074; DOI=10.1126/science.1071006;
RA   Seki M., Narusaka M., Kamiya A., Ishida J., Satou M., Sakurai T.,
RA   Nakajima M., Enju A., Akiyama K., Oono Y., Muramatsu M., Hayashizaki Y.,
RA   Kawai J., Carninci P., Itoh M., Ishii Y., Arakawa T., Shibata K.,
RA   Shinagawa A., Shinozaki K.;
RT   "Functional annotation of a full-length Arabidopsis cDNA collection.";
RL   Science 296:141-145(2002).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000250}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the drug/metabolite transporter (DMT)
CC       superfamily. Plant drug/metabolite exporter (P-DME) (TC 2.A.7.4)
CC       family. {ECO:0000305}.
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DR   EMBL; AP001314; BAB02235.1; -; Genomic_DNA.
DR   EMBL; CP002686; AEE77633.1; -; Genomic_DNA.
DR   EMBL; AK118732; BAC43326.1; -; mRNA.
DR   RefSeq; NP_189653.2; NM_113933.3.
DR   AlphaFoldDB; Q9LI65; -.
DR   SMR; Q9LI65; -.
DR   BioGRID; 8061; 1.
DR   IntAct; Q9LI65; 1.
DR   PaxDb; Q9LI65; -.
DR   PRIDE; Q9LI65; -.
DR   ProteomicsDB; 242469; -.
DR   EnsemblPlants; AT3G30340.1; AT3G30340.1; AT3G30340.
DR   GeneID; 822735; -.
DR   Gramene; AT3G30340.1; AT3G30340.1; AT3G30340.
DR   KEGG; ath:AT3G30340; -.
DR   Araport; AT3G30340; -.
DR   TAIR; locus:2102881; AT3G30340.
DR   eggNOG; ENOG502QU0E; Eukaryota.
DR   HOGENOM; CLU_025359_1_0_1; -.
DR   InParanoid; Q9LI65; -.
DR   OMA; CQYTSTA; -.
DR   OrthoDB; 888469at2759; -.
DR   PhylomeDB; Q9LI65; -.
DR   PRO; PR:Q9LI65; -.
DR   Proteomes; UP000006548; Chromosome 3.
DR   ExpressionAtlas; Q9LI65; baseline and differential.
DR   Genevisible; Q9LI65; AT.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR   GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR   InterPro; IPR000620; EamA_dom.
DR   InterPro; IPR030184; WAT1-related.
DR   PANTHER; PTHR31218; PTHR31218; 1.
DR   Pfam; PF00892; EamA; 2.
PE   2: Evidence at transcript level;
KW   Membrane; Reference proteome; Repeat; Transmembrane; Transmembrane helix.
FT   CHAIN           1..364
FT                   /note="WAT1-related protein At3g30340"
FT                   /id="PRO_0000421332"
FT   TRANSMEM        9..29
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        41..61
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        76..96
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        102..122
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        138..158
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        183..203
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        215..235
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        251..271
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        277..297
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        304..324
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   DOMAIN          26..152
FT                   /note="EamA 1"
FT   DOMAIN          195..323
FT                   /note="EamA 2"
SQ   SEQUENCE   364 AA;  40373 MW;  F667A1E2FD3E1C22 CRC64;
     MVKFDTKLWK AVLMMSMINI GLSVVNVMFK KMIDEGLNRM VATTYRLAVG TLFLIPFAIF
     LERHNRPKLT GRILCSLFFS ALLGTSLVQY FFLIGLEYTS STFSLAFSNM VPSVTFALAL
     VFRQETLNIK SNVGRAKLLG TMICICGALV LTLYKGTALS REHSTHMETH TRTDSTGAMT
     QKWAMGSIML VISIIIWSSW FIVQAKISRV YPCQYTSTTI LSFFGVIQSA LLSLISERST
     SMWVVKDKFQ VLALLYSGIV GSGLCYVGMS WCLRQRGAVF TSSFIPLIQV FAAIFSFSFL
     HEQIYCGSVI GSMVIIVGLY ILLWGKSKDK SASVTKQEPL DLDIEGCGTA PKELNSTAHQ
     VSAK