WTR39_ARATH
ID WTR39_ARATH Reviewed; 377 AA.
AC Q9FNA5; Q84WF1;
DT 06-MAR-2013, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2001, sequence version 1.
DT 03-AUG-2022, entry version 108.
DE RecName: Full=WAT1-related protein At5g13670;
GN OrderedLocusNames=At5g13670; ORFNames=MSH12.14;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=9405937; DOI=10.1093/dnares/4.4.291;
RA Kotani H., Nakamura Y., Sato S., Kaneko T., Asamizu E., Miyajima N.,
RA Tabata S.;
RT "Structural analysis of Arabidopsis thaliana chromosome 5. II. Sequence
RT features of the regions of 1,044,062 bp covered by thirteen physically
RT assigned P1 clones.";
RL DNA Res. 4:291-300(1997).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RA Brover V.V., Troukhan M.E., Alexandrov N.A., Lu Y.-P., Flavell R.B.,
RA Feldmann K.A.;
RT "Full-length cDNA from Arabidopsis thaliana.";
RL Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases.
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 60-377.
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000250}; Multi-pass membrane
CC protein {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the drug/metabolite transporter (DMT)
CC superfamily. Plant drug/metabolite exporter (P-DME) (TC 2.A.7.4)
CC family. {ECO:0000305}.
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DR EMBL; AB006704; BAB08694.1; -; Genomic_DNA.
DR EMBL; CP002688; AED91926.1; -; Genomic_DNA.
DR EMBL; AY084424; AAM60998.1; -; mRNA.
DR EMBL; BT003898; AAO41946.1; -; mRNA.
DR RefSeq; NP_196871.1; NM_121370.3.
DR AlphaFoldDB; Q9FNA5; -.
DR SMR; Q9FNA5; -.
DR PaxDb; Q9FNA5; -.
DR PRIDE; Q9FNA5; -.
DR EnsemblPlants; AT5G13670.1; AT5G13670.1; AT5G13670.
DR GeneID; 831212; -.
DR Gramene; AT5G13670.1; AT5G13670.1; AT5G13670.
DR KEGG; ath:AT5G13670; -.
DR Araport; AT5G13670; -.
DR TAIR; locus:2173189; AT5G13670.
DR eggNOG; ENOG502SHYN; Eukaryota.
DR HOGENOM; CLU_025359_1_1_1; -.
DR InParanoid; Q9FNA5; -.
DR OMA; QMATIND; -.
DR OrthoDB; 813501at2759; -.
DR PhylomeDB; Q9FNA5; -.
DR PRO; PR:Q9FNA5; -.
DR Proteomes; UP000006548; Chromosome 5.
DR ExpressionAtlas; Q9FNA5; baseline and differential.
DR Genevisible; Q9FNA5; AT.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR InterPro; IPR000620; EamA_dom.
DR InterPro; IPR030184; WAT1-related.
DR PANTHER; PTHR31218; PTHR31218; 1.
DR Pfam; PF00892; EamA; 2.
PE 2: Evidence at transcript level;
KW Membrane; Reference proteome; Repeat; Transmembrane; Transmembrane helix.
FT CHAIN 1..377
FT /note="WAT1-related protein At5g13670"
FT /id="PRO_0000421346"
FT TRANSMEM 9..29
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 38..58
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 64..84
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 99..119
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 136..156
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 187..207
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 214..234
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 251..271
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 279..299
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 303..323
FT /note="Helical"
FT /evidence="ECO:0000255"
FT DOMAIN 18..149
FT /note="EamA 1"
FT DOMAIN 194..322
FT /note="EamA 2"
SQ SEQUENCE 377 AA; 41469 MW; 1DA8D350AE74B5FB CRC64;
MKFERARPFI AIVFIQCLYA LMSIVAKLAL NKGMSPHVLV AYRMAVASAL ITPFALILER
NTRPKLTFKI LLQIAILSLF EPVVEQNLYY SGMKLTTATF TSALCNALPA MTFIMACVFK
LEKVTIERRH SQAKLVGTMV AIGGAMLMTF VKGNVIELPW TSNSRGLNGH THAMRIPKQA
DIARGSIMLV ASCFSWSCYI ILQAKILAQY KAELSLTALM CIMGMLEATV MGLIWERKNM
SVWKINPDVT LLASIYGGLV SGLAYYVIGW ASKERGPVFV SAFNPLSMVL VAILSTFVFL
EKVYVGRVIG SVVIVIGIYL VLWGKSKDKG GMLQPNAGCA ETVVKIDQQK VPTPDNNQVV
SISYHLMIPK AAARSQE
