WTR40_ARATH
ID WTR40_ARATH Reviewed; 339 AA.
AC Q945L4; Q9FL11;
DT 06-MAR-2013, integrated into UniProtKB/Swiss-Prot.
DT 01-DEC-2001, sequence version 1.
DT 03-AUG-2022, entry version 105.
DE RecName: Full=WAT1-related protein At5g40210;
GN OrderedLocusNames=At5g40210; ORFNames=MSN9.110;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=9679202; DOI=10.1093/dnares/5.2.131;
RA Kaneko T., Kotani H., Nakamura Y., Sato S., Asamizu E., Miyajima N.,
RA Tabata S.;
RT "Structural analysis of Arabidopsis thaliana chromosome 5. V. Sequence
RT features of the regions of 1,381,565 bp covered by twenty one physically
RT assigned P1 and TAC clones.";
RL DNA Res. 5:131-145(1998).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000250}; Multi-pass membrane
CC protein {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the drug/metabolite transporter (DMT)
CC superfamily. Plant drug/metabolite exporter (P-DME) (TC 2.A.7.4)
CC family. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=BAB10902.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR EMBL; AB010699; BAB10902.1; ALT_SEQ; Genomic_DNA.
DR EMBL; CP002688; AED94520.1; -; Genomic_DNA.
DR EMBL; AF412089; AAL06542.1; -; mRNA.
DR EMBL; BT001013; AAN46767.1; -; mRNA.
DR RefSeq; NP_568578.1; NM_123385.3.
DR AlphaFoldDB; Q945L4; -.
DR BioGRID; 19270; 1.
DR IntAct; Q945L4; 1.
DR PaxDb; Q945L4; -.
DR PRIDE; Q945L4; -.
DR EnsemblPlants; AT5G40210.1; AT5G40210.1; AT5G40210.
DR GeneID; 834019; -.
DR Gramene; AT5G40210.1; AT5G40210.1; AT5G40210.
DR KEGG; ath:AT5G40210; -.
DR Araport; AT5G40210; -.
DR TAIR; locus:2173737; AT5G40210.
DR eggNOG; ENOG502QRQK; Eukaryota.
DR HOGENOM; CLU_025359_0_1_1; -.
DR InParanoid; Q945L4; -.
DR OMA; VIHTWAV; -.
DR OrthoDB; 927776at2759; -.
DR PhylomeDB; Q945L4; -.
DR PRO; PR:Q945L4; -.
DR Proteomes; UP000006548; Chromosome 5.
DR ExpressionAtlas; Q945L4; baseline and differential.
DR Genevisible; Q945L4; AT.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR InterPro; IPR000620; EamA_dom.
DR InterPro; IPR030184; WAT1-related.
DR PANTHER; PTHR31218; PTHR31218; 1.
DR Pfam; PF00892; EamA; 1.
PE 2: Evidence at transcript level;
KW Membrane; Reference proteome; Transmembrane; Transmembrane helix.
FT CHAIN 1..339
FT /note="WAT1-related protein At5g40210"
FT /id="PRO_0000421347"
FT TRANSMEM 11..31
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 42..62
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 74..94
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 104..124
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 140..160
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 168..188
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 200..220
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 233..253
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 266..286
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 289..309
FT /note="Helical"
FT /evidence="ECO:0000255"
FT DOMAIN 29..154
FT /note="EamA"
SQ SEQUENCE 339 AA; 36577 MW; D3C0F20E71AD3B77 CRC64;
MVHGRLCNRD GWILTAMVVT EFSNVGVNTL VKAATSKGLS PFVVLVYSYT FGSLLLLPLT
FFSFRSRSLP PLTFSILCNM GILGLIASAF QILGYNGIKY SSPTLSSAMS NVNPAFTFIL
AVVFRMENIS LGKKSSVAKV LGTILSIIGA LVVTLYHGPM LMSSHSDWII GGGLLALQYI
LVSVSYLVMA HTMGRYPSAV VVTLVHNVCI AVVCAFVSLL AEKDNPKAWV IRFDITLITV
VATGILNSGY YVIHTWAVSH KGPVYLSMFK PLSILIAAVS TFIFLGESLY LGSVMGGILI
SIGFYMVLWG KAKEDKVDII GAIESSPSHN APLLDNFKS
