WTR42_ARATH
ID WTR42_ARATH Reviewed; 368 AA.
AC Q9FL08;
DT 06-MAR-2013, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2001, sequence version 1.
DT 03-AUG-2022, entry version 107.
DE RecName: Full=WAT1-related protein At5g40240;
GN OrderedLocusNames=At5g40240; ORFNames=MSN9.140;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=9679202; DOI=10.1093/dnares/5.2.131;
RA Kaneko T., Kotani H., Nakamura Y., Sato S., Asamizu E., Miyajima N.,
RA Tabata S.;
RT "Structural analysis of Arabidopsis thaliana chromosome 5. V. Sequence
RT features of the regions of 1,381,565 bp covered by twenty one physically
RT assigned P1 and TAC clones.";
RL DNA Res. 5:131-145(1998).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RA Totoki Y., Seki M., Ishida J., Nakajima M., Enju A., Kamiya A.,
RA Narusaka M., Shin-i T., Nakagawa M., Sakamoto N., Oishi K., Kohara Y.,
RA Kobayashi M., Toyoda A., Sakaki Y., Sakurai T., Iida K., Akiyama K.,
RA Satou M., Toyoda T., Konagaya A., Carninci P., Kawai J., Hayashizaki Y.,
RA Shinozaki K.;
RT "Large-scale analysis of RIKEN Arabidopsis full-length (RAFL) cDNAs.";
RL Submitted (JUL-2006) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000250}; Multi-pass membrane
CC protein {ECO:0000305}.
CC -!- ALTERNATIVE PRODUCTS:
CC Event=Alternative splicing; Named isoforms=1;
CC Comment=Additional isoforms seem to exist.;
CC Name=1;
CC IsoId=Q9FL08-1; Sequence=Displayed;
CC -!- SIMILARITY: Belongs to the drug/metabolite transporter (DMT)
CC superfamily. Plant drug/metabolite exporter (P-DME) (TC 2.A.7.4)
CC family. {ECO:0000305}.
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DR EMBL; AB010699; BAB10905.1; -; Genomic_DNA.
DR EMBL; CP002688; AED94523.1; -; Genomic_DNA.
DR EMBL; CP002688; ANM69648.1; -; Genomic_DNA.
DR EMBL; BT008312; AAP37671.1; -; mRNA.
DR EMBL; AK227665; BAE99652.1; -; mRNA.
DR RefSeq; NP_001318710.1; NM_001344317.1. [Q9FL08-1]
DR RefSeq; NP_198840.2; NM_123388.5. [Q9FL08-1]
DR AlphaFoldDB; Q9FL08; -.
DR STRING; 3702.AT5G40240.2; -.
DR iPTMnet; Q9FL08; -.
DR PaxDb; Q9FL08; -.
DR PRIDE; Q9FL08; -.
DR EnsemblPlants; AT5G40240.1; AT5G40240.1; AT5G40240. [Q9FL08-1]
DR EnsemblPlants; AT5G40240.3; AT5G40240.3; AT5G40240. [Q9FL08-1]
DR GeneID; 834022; -.
DR Gramene; AT5G40240.1; AT5G40240.1; AT5G40240. [Q9FL08-1]
DR Gramene; AT5G40240.3; AT5G40240.3; AT5G40240. [Q9FL08-1]
DR KEGG; ath:AT5G40240; -.
DR Araport; AT5G40240; -.
DR eggNOG; ENOG502RNNC; Eukaryota.
DR HOGENOM; CLU_025359_0_1_1; -.
DR InParanoid; Q9FL08; -.
DR OMA; IWYIVQA; -.
DR PhylomeDB; Q9FL08; -.
DR PRO; PR:Q9FL08; -.
DR Proteomes; UP000006548; Chromosome 5.
DR ExpressionAtlas; Q9FL08; baseline and differential.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR InterPro; IPR000620; EamA_dom.
DR InterPro; IPR030184; WAT1-related.
DR PANTHER; PTHR31218; PTHR31218; 1.
DR Pfam; PF00892; EamA; 2.
PE 2: Evidence at transcript level;
KW Alternative splicing; Membrane; Reference proteome; Repeat; Transmembrane;
KW Transmembrane helix.
FT CHAIN 1..368
FT /note="WAT1-related protein At5g40240"
FT /id="PRO_0000421349"
FT TRANSMEM 18..38
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 50..70
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 82..102
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 111..131
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 142..162
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 194..214
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 226..246
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 260..280
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 292..312
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 315..335
FT /note="Helical"
FT /evidence="ECO:0000255"
FT DOMAIN 33..161
FT /note="EamA 1"
FT DOMAIN 208..334
FT /note="EamA 2"
SQ SEQUENCE 368 AA; 40094 MW; CCF32EBC00C90AE0 CRC64;
MREAGEEKVA WKYFTRDVVP FAAMFAVECA TVGSNTLFKA ATLRGLSFYV FVFYSYIVST
LLLLPLSVIF GRSRRLPAAK SPLFFKIFLL GLVGFMSQIA GCKGIAYSSP TLASAISNLT
PAFTFTLAVI FRMEQVRLRS SATQAKIIGA ILSISGALVV VLYKGPQVLA SASFTTVLPT
VTLHQQLTSI ESSWIIGGLL LASQYFLISV WYILQTRVME VYPEEITVVF FYNLFATLIS
VPVCLFAESN LTSWVLKPDI SLAAIIYSGV FVSLFSALTH TWGLHLKGPV YISLFRPLSI
AIAVAMGAIF LGDALHLGSV IGSMILCIGF YTVIWGKARE DTIKTVAGSE QSPLLLTHII
EDGAFPLS
