ID   WTR44_ARATH             Reviewed;         364 AA.
AC   Q9FGL0;
DT   06-MAR-2013, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2001, sequence version 1.
DT   03-AUG-2022, entry version 98.
DE   RecName: Full=WAT1-related protein At5g47470;
GN   OrderedLocusNames=At5g47470; ORFNames=MNJ7.6;
OS   Arabidopsis thaliana (Mouse-ear cress).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX   NCBI_TaxID=3702;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Columbia;
RA   Kaneko T., Katoh T., Asamizu E., Sato S., Nakamura Y., Kotani H.,
RA   Tabata S.;
RT   "Structural analysis of Arabidopsis thaliana chromosome 5. XI.";
RL   Submitted (APR-1999) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Columbia;
RX   PubMed=27862469; DOI=10.1111/tpj.13415;
RA   Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA   Town C.D.;
RT   "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT   genome.";
RL   Plant J. 89:789-804(2017).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000250}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the drug/metabolite transporter (DMT)
CC       superfamily. Plant drug/metabolite exporter (P-DME) (TC 2.A.7.4)
CC       family. {ECO:0000305}.
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DR   EMBL; AB025628; BAB09073.1; -; Genomic_DNA.
DR   EMBL; CP002688; AED95523.1; -; Genomic_DNA.
DR   RefSeq; NP_199558.1; NM_124120.1.
DR   AlphaFoldDB; Q9FGL0; -.
DR   STRING; 3702.AT5G47470.1; -.
DR   PaxDb; Q9FGL0; -.
DR   PRIDE; Q9FGL0; -.
DR   EnsemblPlants; AT5G47470.1; AT5G47470.1; AT5G47470.
DR   GeneID; 834797; -.
DR   Gramene; AT5G47470.1; AT5G47470.1; AT5G47470.
DR   KEGG; ath:AT5G47470; -.
DR   Araport; AT5G47470; -.
DR   TAIR; locus:2168978; AT5G47470.
DR   eggNOG; ENOG502QVME; Eukaryota.
DR   HOGENOM; CLU_025359_1_2_1; -.
DR   InParanoid; Q9FGL0; -.
DR   OMA; TWAKIVG; -.
DR   PhylomeDB; Q9FGL0; -.
DR   PRO; PR:Q9FGL0; -.
DR   Proteomes; UP000006548; Chromosome 5.
DR   ExpressionAtlas; Q9FGL0; baseline and differential.
DR   Genevisible; Q9FGL0; AT.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR   GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR   InterPro; IPR000620; EamA_dom.
DR   InterPro; IPR030184; WAT1-related.
DR   PANTHER; PTHR31218; PTHR31218; 1.
DR   Pfam; PF00892; EamA; 2.
PE   3: Inferred from homology;
KW   Membrane; Reference proteome; Repeat; Transmembrane; Transmembrane helix.
FT   CHAIN           1..364
FT                   /note="WAT1-related protein At5g47470"
FT                   /id="PRO_0000421351"
FT   TRANSMEM        28..48
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        59..79
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        93..113
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        124..144
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        158..178
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        197..217
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        228..248
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        255..275
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        293..313
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        319..339
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   DOMAIN          40..172
FT                   /note="EamA 1"
FT   DOMAIN          219..338
FT                   /note="EamA 2"
SQ   SEQUENCE   364 AA;  39558 MW;  A496446608640918 CRC64;
     MQFFCVNLYR SVLNLLEERM KTEMIEEMVI VGGLVMVQFV YAGNSLLMSY LMSLGLGPFT
     IVIFSTFATF IILSPFAILF ERKQWPNELS LRLIGKLVLI SFAGVTLFQS LFLEGIRLTS
     PAMATAMPNL APGLIFFIAW IVGLEKMNLK CVYSKLKILG TLLCVFGALA MSVMHSTSIS
     HKEEDDTPIF VFDRDKVVGC IYLLGAVFVL STNVVLQAST LAEFPAPISL SAITALLGVL
     ITTVVLLLQN RKTKVLASSL ISFGNLVGYS VLAGAVSGAC VSFNGWAMKK RGPVFVSMFS
     PFATVISVAF AVLTLGESVS LGSVGGMVLM FVGLYLVLWA KGKEGFSEIE SFESEFDSKK
     PLLS