WUS_SOLLC
ID WUS_SOLLC Reviewed; 272 AA.
AC Q84VT7;
DT 15-MAR-2005, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-2003, sequence version 1.
DT 03-AUG-2022, entry version 85.
DE RecName: Full=Protein WUSCHEL;
DE AltName: Full=LeWUS;
GN Name=WUS;
OS Solanum lycopersicum (Tomato) (Lycopersicon esculentum).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; lamiids; Solanales; Solanaceae; Solanoideae; Solaneae; Solanum;
OC Solanum subgen. Lycopersicon.
OX NCBI_TaxID=4081;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA], AND TISSUE SPECIFICITY.
RC TISSUE=Meristem;
RX PubMed=12874128; DOI=10.1242/dev.00596;
RA Reinhardt D., Frenz M., Mandel T., Kuhlemeier C.;
RT "Microsurgical and laser ablation analysis of interactions between the
RT zones and layers of the tomato shoot apical meristem.";
RL Development 130:4073-4083(2003).
CC -!- FUNCTION: Transcription factor that plays a central role during
CC developmental processes such as early embryogenesis and flowering,
CC probably by regulating expression of specific genes. Required to
CC specify stem cell identity in meristems, such as shoot apical meristem
CC (SAM). May induce shoot stem cells activity in order to maintain the
CC stem cell identity (By similarity). {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00108}.
CC -!- TISSUE SPECIFICITY: Expressed in the central zone of the active shoot
CC meristem. {ECO:0000269|PubMed:12874128}.
CC -!- SIMILARITY: Belongs to the WUS homeobox family. {ECO:0000305}.
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DR EMBL; AJ538329; CAD61961.1; -; mRNA.
DR RefSeq; NP_001234015.2; NM_001247086.3.
DR AlphaFoldDB; Q84VT7; -.
DR SMR; Q84VT7; -.
DR STRING; 4081.Solyc02g083950.2.1; -.
DR PaxDb; Q84VT7; -.
DR PRIDE; Q84VT7; -.
DR GeneID; 543793; -.
DR KEGG; sly:543793; -.
DR eggNOG; ENOG502QRYV; Eukaryota.
DR InParanoid; Q84VT7; -.
DR OrthoDB; 1155487at2759; -.
DR Proteomes; UP000004994; Unplaced.
DR ExpressionAtlas; Q84VT7; differential.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR GO; GO:0009908; P:flower development; IEA:UniProtKB-KW.
DR GO; GO:0099402; P:plant organ development; IEA:InterPro.
DR CDD; cd00086; homeodomain; 1.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR001356; Homeobox_dom.
DR InterPro; IPR044555; WUSCHEL-like.
DR PANTHER; PTHR45940; PTHR45940; 1.
DR Pfam; PF00046; Homeodomain; 1.
DR SMART; SM00389; HOX; 1.
DR SUPFAM; SSF46689; SSF46689; 1.
DR PROSITE; PS50071; HOMEOBOX_2; 1.
PE 2: Evidence at transcript level;
KW Developmental protein; Differentiation; DNA-binding; Flowering; Homeobox;
KW Nucleus; Reference proteome; Transcription; Transcription regulation.
FT CHAIN 1..272
FT /note="Protein WUSCHEL"
FT /id="PRO_0000049384"
FT DNA_BIND 22..87
FT /note="Homeobox; WUS-type"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00108"
FT REGION 1..24
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 10..24
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 272 AA; 31001 MW; C335B7612AB29C68 CRC64;
MEHQHNIEDG GKNSNNSFLC RQSSSRWTPT SDQIRILKDL YYNNGVRSPT AEQIQRISAK
LRQYGKIEGK NVFYWFQNHK ARERQKKRLI AAASATDNNN ISSMQMIPHL WRSPDDHHKY
NTATTNPGVQ CPSPSSHGVL PVVQTGNYGY GTLAMEKSFR ECSISPPGGS YHQNLTWVGV
DPYNNMSTTS PATYPFLEKS NNKHYEETLD EEQEEENYQR GNSALETLSL FPMHEENIIS
NFCIKHHESS GGWYHSDNNN LAALELTLNS FP
