ID   WZA_SALTY               Reviewed;         379 AA.
AC   Q8ZNQ9; Q9F7B3;
DT   27-MAR-2002, integrated into UniProtKB/Swiss-Prot.
DT   27-MAR-2002, sequence version 1.
DT   03-AUG-2022, entry version 109.
DE   RecName: Full=Putative polysaccharide export protein wza;
DE   Flags: Precursor;
GN   Name=wza; OrderedLocusNames=STM2118;
OS   Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Salmonella.
OX   NCBI_TaxID=99287;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=LT2;
RX   PubMed=11004393; DOI=10.1111/j.1574-6968.2000.tb09312.x;
RA   Stevenson G., Lan R., Reeves P.R.;
RT   "The colanic acid gene cluster of Salmonella enterica has a complex
RT   history.";
RL   FEMS Microbiol. Lett. 191:11-16(2000).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=LT2 / SGSC1412 / ATCC 700720;
RX   PubMed=11677609; DOI=10.1038/35101614;
RA   McClelland M., Sanderson K.E., Spieth J., Clifton S.W., Latreille P.,
RA   Courtney L., Porwollik S., Ali J., Dante M., Du F., Hou S., Layman D.,
RA   Leonard S., Nguyen C., Scott K., Holmes A., Grewal N., Mulvaney E.,
RA   Ryan E., Sun H., Florea L., Miller W., Stoneking T., Nhan M., Waterston R.,
RA   Wilson R.K.;
RT   "Complete genome sequence of Salmonella enterica serovar Typhimurium LT2.";
RL   Nature 413:852-856(2001).
CC   -!- FUNCTION: Probably involved in the export of the extracellular
CC       polysaccharide colanic acid from the cell to medium. {ECO:0000250}.
CC   -!- PATHWAY: Glycan metabolism; exopolysaccharide biosynthesis.
CC   -!- SUBCELLULAR LOCATION: Cell outer membrane {ECO:0000250}; Multi-pass
CC       membrane protein {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the BexD/CtrA/VexA family. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAG24804.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR   EMBL; AF285084; AAG24804.1; ALT_INIT; Genomic_DNA.
DR   EMBL; AE006468; AAL21022.1; -; Genomic_DNA.
DR   RefSeq; NP_461063.1; NC_003197.2.
DR   RefSeq; WP_000978077.1; NC_003197.2.
DR   AlphaFoldDB; Q8ZNQ9; -.
DR   SMR; Q8ZNQ9; -.
DR   STRING; 99287.STM2118; -.
DR   PaxDb; Q8ZNQ9; -.
DR   EnsemblBacteria; AAL21022; AAL21022; STM2118.
DR   GeneID; 1253639; -.
DR   KEGG; stm:STM2118; -.
DR   PATRIC; fig|99287.12.peg.2240; -.
DR   HOGENOM; CLU_038343_4_2_6; -.
DR   OMA; TKGGQFY; -.
DR   PhylomeDB; Q8ZNQ9; -.
DR   BioCyc; SENT99287:STM2118-MON; -.
DR   UniPathway; UPA00631; -.
DR   Proteomes; UP000001014; Chromosome.
DR   GO; GO:0009279; C:cell outer membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0046930; C:pore complex; IEA:UniProtKB-KW.
DR   GO; GO:0015159; F:polysaccharide transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0015288; F:porin activity; IEA:UniProtKB-KW.
DR   GO; GO:0006811; P:ion transport; IEA:UniProtKB-KW.
DR   GO; GO:0000271; P:polysaccharide biosynthetic process; IEA:UniProtKB-KW.
DR   InterPro; IPR003715; Poly_export.
DR   InterPro; IPR019554; Soluble_ligand-bd.
DR   InterPro; IPR040716; Wza_C.
DR   Pfam; PF02563; Poly_export; 1.
DR   Pfam; PF10531; SLBB; 1.
DR   Pfam; PF18412; Wza_C; 1.
DR   PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE   3: Inferred from homology;
KW   Cell outer membrane; Exopolysaccharide synthesis; Ion transport;
KW   Lipoprotein; Membrane; Palmitate; Polysaccharide transport; Porin;
KW   Reference proteome; Signal; Sugar transport; Transmembrane;
KW   Transmembrane beta strand; Transport.
FT   SIGNAL          1..20
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00303"
FT   CHAIN           21..379
FT                   /note="Putative polysaccharide export protein wza"
FT                   /id="PRO_0000025225"
FT   LIPID           21
FT                   /note="N-palmitoyl cysteine"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00303"
FT   LIPID           21
FT                   /note="S-diacylglycerol cysteine"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00303"
FT   CONFLICT        161
FT                   /note="V -> W (in Ref. 1; AAG24804)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   379 AA;  41703 MW;  6B94D0C9453D80DD CRC64;
     MMKSKMKLMP LLASLSLISG CTVLPGSNMS TMGKDVIKQQ DADFDLDRMV NVYPLTPRLV
     EQLRPRPNVA QPNMSLDQEI ASYQYRVGPG DVLNVTVWDH PELTTPAGQY RSSSDTGNWV
     QPDGTMFYPY IGKVSVVGKT LSEIRSDITG RLAKYIADPQ VDVNIAAFRS QKAYISGQVN
     KSGQQAITNV PLTVLDAINA AGGLTDMADW RNVVLTHNGK EQRISLQALM QNGDLSQNRL
     LYPGDILYVP RNDDLKVFVM GEVKKQSTLK MDFSGMTLTE ALGNAEGIDL TTSNASGIFV
     IRPLKGEGGR GGKIANIYQL DMSDATSLVM ATEFRLQPYD VVYVTTAPVA RWNRLINQLL
     PTISGVRYMT DTASDIHSW