ID   WZYE_ERWT9              Reviewed;         457 AA.
AC   B2VG51;
DT   14-APR-2009, integrated into UniProtKB/Swiss-Prot.
DT   01-JUL-2008, sequence version 1.
DT   25-MAY-2022, entry version 67.
DE   RecName: Full=Probable ECA polymerase {ECO:0000255|HAMAP-Rule:MF_01003};
GN   Name=wzyE {ECO:0000255|HAMAP-Rule:MF_01003}; OrderedLocusNames=ETA_02070;
OS   Erwinia tasmaniensis (strain DSM 17950 / CFBP 7177 / CIP 109463 / NCPPB
OS   4357 / Et1/99).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Erwiniaceae; Erwinia.
OX   NCBI_TaxID=465817;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 17950 / CFBP 7177 / CIP 109463 / NCPPB 4357 / Et1/99;
RX   PubMed=18462403; DOI=10.1111/j.1462-2920.2008.01639.x;
RA   Kube M., Migdoll A.M., Mueller I., Kuhl H., Beck A., Reinhardt R.,
RA   Geider K.;
RT   "The genome of Erwinia tasmaniensis strain Et1/99, a non-pathogenic
RT   bacterium in the genus Erwinia.";
RL   Environ. Microbiol. 10:2211-2222(2008).
CC   -!- FUNCTION: Probably involved in the polymerization of enterobacterial
CC       common antigen (ECA) trisaccharide repeat units. {ECO:0000255|HAMAP-
CC       Rule:MF_01003}.
CC   -!- PATHWAY: Bacterial outer membrane biogenesis; enterobacterial common
CC       antigen biosynthesis. {ECO:0000255|HAMAP-Rule:MF_01003}.
CC   -!- SUBUNIT: Probably part of a complex composed of WzxE, WzyE and WzzE.
CC       {ECO:0000255|HAMAP-Rule:MF_01003}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000255|HAMAP-
CC       Rule:MF_01003}; Multi-pass membrane protein {ECO:0000255|HAMAP-
CC       Rule:MF_01003}.
CC   -!- SIMILARITY: Belongs to the WzyE family. {ECO:0000255|HAMAP-
CC       Rule:MF_01003}.
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DR   EMBL; CU468135; CAO95253.1; -; Genomic_DNA.
DR   RefSeq; WP_012439973.1; NC_010694.1.
DR   AlphaFoldDB; B2VG51; -.
DR   STRING; 465817.ETA_02070; -.
DR   EnsemblBacteria; CAO95253; CAO95253; ETA_02070.
DR   KEGG; eta:ETA_02070; -.
DR   eggNOG; ENOG502Z7MA; Bacteria.
DR   HOGENOM; CLU_049711_0_0_6; -.
DR   OMA; WLWPDRP; -.
DR   OrthoDB; 614230at2; -.
DR   UniPathway; UPA00566; -.
DR   Proteomes; UP000001726; Chromosome.
DR   GO; GO:0005887; C:integral component of plasma membrane; IEA:UniProtKB-UniRule.
DR   GO; GO:0009246; P:enterobacterial common antigen biosynthetic process; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_01003; WzyE; 1.
DR   InterPro; IPR010691; WzyE.
DR   Pfam; PF06899; WzyE; 1.
PE   3: Inferred from homology;
KW   Cell inner membrane; Cell membrane; Membrane; Reference proteome;
KW   Transmembrane; Transmembrane helix.
FT   CHAIN           1..457
FT                   /note="Probable ECA polymerase"
FT                   /id="PRO_1000200202"
FT   TRANSMEM        3..23
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01003"
FT   TRANSMEM        41..61
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01003"
FT   TRANSMEM        65..85
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01003"
FT   TRANSMEM        118..138
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01003"
FT   TRANSMEM        154..174
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01003"
FT   TRANSMEM        181..201
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01003"
FT   TRANSMEM        206..226
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01003"
FT   TRANSMEM        227..247
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01003"
FT   TRANSMEM        340..360
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01003"
FT   TRANSMEM        377..397
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01003"
FT   TRANSMEM        408..428
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01003"
SQ   SEQUENCE   457 AA;  52206 MW;  1EC629BE31D41E4D CRC64;
     MTLLQFAGLL LVWLVCGGFI LTLTWREFRR VRFNFNVFFS MLFLLTFFFG FPLTCILVFG
     FDVEVVPAEY LLQALLSAGC FYAIYYVTYK TRLRTRHRAP SRPAFTINRI EAHLSWMIMA
     LVALITVSVF FLHNGFLLFK LQKYSQIFSA DVSGVALKRF FYFFIPAMLV VYFLQQNMRS
     WLLFLVGTVA FGLLTYAIVG GTRANIIIAF ALFLFIGIIR GWITLWMLAL AGVGAIVAMF
     WLALKRYNLD VSGSQAFYTF LYLTRDTFSP WENLGLLLQN YDRIDFQGLA PVWRDFYVFI
     PSWLWHERPS VVLNSANYFT WEVLDNHSGL AISPTLIGSL VVMGGALFIM LGAVMVGLII
     KWFDWLYEKG RQEENPYKAA ILQSFCFGAV FNMIVLAREG LDAFVSRVVF FCVIFAACVL
     VAKLLYWLLD SAGLVRARKG PACARSSLKH CFVGNDS