ID   WZYE_PECCP              Reviewed;         463 AA.
AC   C6DHE3;
DT   22-SEP-2009, integrated into UniProtKB/Swiss-Prot.
DT   01-SEP-2009, sequence version 1.
DT   25-MAY-2022, entry version 56.
DE   RecName: Full=Probable ECA polymerase {ECO:0000255|HAMAP-Rule:MF_01003};
GN   Name=wzyE {ECO:0000255|HAMAP-Rule:MF_01003}; OrderedLocusNames=PC1_4001;
OS   Pectobacterium carotovorum subsp. carotovorum (strain PC1).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Pectobacteriaceae; Pectobacterium.
OX   NCBI_TaxID=561230;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=PC1;
RG   US DOE Joint Genome Institute;
RA   Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Tice H., Bruce D.,
RA   Goodwin L., Pitluck S., Munk A.C., Brettin T., Detter J.C., Han C.,
RA   Tapia R., Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N.,
RA   Balakrishnan V., Glasner J., Perna N.T.;
RT   "Complete sequence of Pectobacterium carotovorum subsp. carotovorum PC1.";
RL   Submitted (JUL-2009) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Probably involved in the polymerization of enterobacterial
CC       common antigen (ECA) trisaccharide repeat units. {ECO:0000255|HAMAP-
CC       Rule:MF_01003}.
CC   -!- PATHWAY: Bacterial outer membrane biogenesis; enterobacterial common
CC       antigen biosynthesis. {ECO:0000255|HAMAP-Rule:MF_01003}.
CC   -!- SUBUNIT: Probably part of a complex composed of WzxE, WzyE and WzzE.
CC       {ECO:0000255|HAMAP-Rule:MF_01003}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000255|HAMAP-
CC       Rule:MF_01003}; Multi-pass membrane protein {ECO:0000255|HAMAP-
CC       Rule:MF_01003}.
CC   -!- SIMILARITY: Belongs to the WzyE family. {ECO:0000255|HAMAP-
CC       Rule:MF_01003}.
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DR   EMBL; CP001657; ACT15016.1; -; Genomic_DNA.
DR   RefSeq; WP_015842096.1; NC_012917.1.
DR   AlphaFoldDB; C6DHE3; -.
DR   STRING; 561230.PC1_4001; -.
DR   EnsemblBacteria; ACT15016; ACT15016; PC1_4001.
DR   KEGG; pct:PC1_4001; -.
DR   eggNOG; ENOG502Z7MA; Bacteria.
DR   HOGENOM; CLU_049711_0_0_6; -.
DR   OMA; WLWPDRP; -.
DR   OrthoDB; 614230at2; -.
DR   UniPathway; UPA00566; -.
DR   Proteomes; UP000002736; Chromosome.
DR   GO; GO:0005887; C:integral component of plasma membrane; IEA:UniProtKB-UniRule.
DR   GO; GO:0009246; P:enterobacterial common antigen biosynthetic process; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_01003; WzyE; 1.
DR   InterPro; IPR010691; WzyE.
DR   Pfam; PF06899; WzyE; 1.
PE   3: Inferred from homology;
KW   Cell inner membrane; Cell membrane; Membrane; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..463
FT                   /note="Probable ECA polymerase"
FT                   /id="PRO_1000213142"
FT   TRANSMEM        6..26
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01003"
FT   TRANSMEM        39..59
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01003"
FT   TRANSMEM        65..85
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01003"
FT   TRANSMEM        112..132
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01003"
FT   TRANSMEM        154..174
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01003"
FT   TRANSMEM        180..200
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01003"
FT   TRANSMEM        201..221
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01003"
FT   TRANSMEM        222..242
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01003"
FT   TRANSMEM        340..360
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01003"
FT   TRANSMEM        377..397
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01003"
FT   TRANSMEM        408..428
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01003"
SQ   SEQUENCE   463 AA;  52882 MW;  3452B8F106D0425A CRC64;
     MTLGQFGGLF VVYLISVIFI LSLTWMEFRR VRFNFNVLFS LLYLLTFYFG FPFTCVLVFR
     FGVDVVPVQF LLQAMLSATA FYAIYYVSYK TRLRQKTSVP RAPLLTVNRV EANLTWLLLA
     LIAVATVGIF FLNNGFLLFK LRSYSQIFSS DVSGVALKRF FYFFIPAMLV VYFLRQTQRA
     WLMFLIGTVA FGMLTYVIVG GTRANLIIAF ALFLFIGIVR GWITLWMLVA AGAFGIVGMF
     WLALKRYGLD VSGDYAFYTF LYLTRDTFSP WENLALLWQN YDKIEFQGLA PIARDFYVFI
     PSWLWPDRPN LVLNSANYFT WEVLNNHSGL AISPTLLGSL VVMGGVLFIP LGAIAVGLVI
     KWFDWVYELG KNDSNRYKAA ILQAFCFGAV FNIIVLTREG VDSFVSRVVF FCLVFGLCLL
     VAKLLYWLLE SAGLIRQRLM RMRATPLVPT PNTVPDPVIK EQL