W_SENDH
ID W_SENDH Reviewed; 318 AA.
AC P69281;
DT 15-MAR-2005, integrated into UniProtKB/Swiss-Prot.
DT 15-MAR-2005, sequence version 1.
DT 02-JUN-2021, entry version 38.
DE RecName: Full=Protein W;
GN Name=P/V/C;
OS Sendai virus (strain Harris) (SeV).
OC Viruses; Riboviria; Orthornavirae; Negarnaviricota; Haploviricotina;
OC Monjiviricetes; Mononegavirales; Paramyxoviridae; Orthoparamyxovirinae;
OC Respirovirus.
OX NCBI_TaxID=11196;
OH NCBI_TaxID=10144; Cavia cutleri (Guinea pig).
OH NCBI_TaxID=36483; Cricetidae sp. (Hamster).
OH NCBI_TaxID=10090; Mus musculus (Mouse).
OH NCBI_TaxID=10116; Rattus norvegicus (Rat).
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC RNA].
RX PubMed=6317203; DOI=10.1016/0092-8674(83)90115-0;
RA Giorgi C., Blumberg B.M., Kolakofsky D.;
RT "Sendai virus contains overlapping genes expressed from a single mRNA.";
RL Cell 35:829-836(1983).
RN [2]
RP NUCLEOTIDE SEQUENCE [GENOMIC RNA], AND VARIANT THR-311.
RA Kolakofsky D.;
RL Submitted (JAN-2005) to UniProtKB.
RN [3]
RP RNA EDITING.
RX PubMed=9034340; DOI=10.1093/emboj/16.3.578;
RA Kato A., Kiyotani K., Sakai Y., Yoshida T., Nagai Y.;
RT "The paramyxovirus, Sendai virus, V protein encodes a luxury function
RT required for viral pathogenesis.";
RL EMBO J. 16:578-587(1997).
CC -!- RNA EDITING: Modified_positions=318 {ECO:0000269|PubMed:9034340};
CC Note=Partially edited. RNA editing at this position consists of an
CC insertion of one or two guanine nucleotides. The sequence displayed
CC here is the W protein, derived from the +2G edited RNA. The unedited
CC RNA gives rise to the P protein (AC P04859), the +1G edited RNA gives
CC rise to the V protein (AC P69280).;
CC -!- MISCELLANEOUS: The P/V/C gene has two overlapping open reading frames.
CC One encodes the P/V/W proteins and the other the C/Y proteins.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
PE 3: Inferred from homology;
KW Phosphoprotein; RNA editing.
FT CHAIN 1..318
FT /note="Protein W"
FT /id="PRO_0000142835"
FT REGION 1..23
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 38..318
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..22
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 48..62
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 86..107
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 115..129
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 147..174
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 233..275
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 277..291
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MOD_RES 68
FT /note="Phosphoserine; by host"
FT /evidence="ECO:0000250"
FT MOD_RES 125
FT /note="Phosphoserine; by host"
FT /evidence="ECO:0000250"
FT MOD_RES 192
FT /note="Phosphoserine; by host"
FT /evidence="ECO:0000250"
FT MOD_RES 249
FT /note="Phosphoserine; by host"
FT /evidence="ECO:0000250"
FT MOD_RES 257
FT /note="Phosphoserine; by host"
FT /evidence="ECO:0000250"
FT MOD_RES 260
FT /note="Phosphoserine; by host"
FT /evidence="ECO:0000250"
FT VARIANT 311
FT /note="S -> T"
FT /evidence="ECO:0000269|Ref.2"
SQ SEQUENCE 318 AA; 33533 MW; 5FEB9EA68D8CF8DD CRC64;
MDQDAFILKE DSEVEREAPG GRESLSDVIG FLDAVLSSEP TDIGGDRSWL HNTINTPQGP
GSAHRAKSEG EGEVSTPSTQ DNRSGEESRV SGRTSKPEAE AHAGNLDKQN IHRAFGGRTG
TNSVSQDLGD GGDSGILENP PNERGYPRSG IEDENREMAA HPDKRGEDQA EGLPEEVRGG
TSLPDEGEGG ASNNGRSMEP GSSHSARVTG VLVIPSPELE EAVLRRNKRR PTNSGSKPLT
PATVPGTRSP PLNRYNSTGS PPGKPPSTQD EHINSGDTPA VRVKDRKPPI GTRSVSDCPA
NGRPIHPGLE SDSTKKGA
