XA1_XENLA
ID XA1_XENLA Reviewed; 198 AA.
AC P23507;
DT 01-NOV-1991, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1991, sequence version 1.
DT 03-AUG-2022, entry version 53.
DE RecName: Full=Protein XA-1;
DE Flags: Precursor;
OS Xenopus laevis (African clawed frog).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus.
OX NCBI_TaxID=8355;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RX PubMed=1723941; DOI=10.1242/dev.110.2.325;
RA Hemmati-Brivanlou A., Frank D., Bolce M.E., Brown B.D., Sive H.L.,
RA Harland R.M.;
RT "Localization of specific mRNAs in Xenopus embryos by whole-mount in situ
RT hybridization.";
RL Development 110:325-330(1990).
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000305}.
CC -!- TISSUE SPECIFICITY: Expressed in the periphery of the cement gland as
CC well as in the region of the hatching gland.
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DR EMBL; X53821; CAA37818.1; -; mRNA.
DR PIR; S14456; S14456.
DR RefSeq; NP_001095221.1; NM_001101751.1.
DR AlphaFoldDB; P23507; -.
DR PRIDE; P23507; -.
DR GeneID; 394411; -.
DR KEGG; xla:394411; -.
DR CTD; 394411; -.
DR Xenbase; XB-GENE-6254220; xa-1.L.
DR OrthoDB; 1782088at2759; -.
DR Proteomes; UP000186698; Chromosome 7L.
DR Bgee; 394411; Expressed in neurula embryo and 5 other tissues.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
PE 2: Evidence at transcript level;
KW Reference proteome; Secreted; Signal.
FT SIGNAL 1..18
FT CHAIN 19..198
FT /note="Protein XA-1"
FT /id="PRO_0000022691"
FT REGION 17..198
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 28..45
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 70..88
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 97..121
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 144..163
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 179..198
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 198 AA; 21995 MW; A121CB75C6AAD1D3 CRC64;
MFFYVLLLAL MAQGWSLPQG KTGEDSPVFR PPSPPMGPSL PPPVSHDLHR PSGHPEEFRT
GASLPPKETP NEPRHGRPKR DLHHGKVVPT GVPHHTGEVL HHTDCSSNTH KSHEENRPKG
FRTGRPLLPI KPEHGRHRRD LHHGKAVPTG VPHHTEKFHN GSNGKSHPPR PGHSTSAHND
NSSEEKRPKH GQEQGKKH