ID   XB33_ORYSJ              Reviewed;         520 AA.
AC   Q337A0; C7J825; Q109E0; Q109E1; Q8LNI4; Q9FWB4;
DT   13-JUL-2010, integrated into UniProtKB/Swiss-Prot.
DT   22-AUG-2006, sequence version 1.
DT   03-AUG-2022, entry version 93.
DE   RecName: Full=Probable E3 ubiquitin-protein ligase XBOS33;
DE            EC=2.3.2.27;
DE   AltName: Full=Ankyrin repeat domain and RING finger-containing protein XBOS33;
DE   AltName: Full=RING-type E3 ubiquitin transferase XBOS33;
DE   AltName: Full=XB3 protein homolog 3;
GN   Name=XBOS33; OrderedLocusNames=Os10g0521600, LOC_Os10g37730;
GN   ORFNames=OSJNBb0018B10.26, OSJNBb0028C01.29;
OS   Oryza sativa subsp. japonica (Rice).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC   Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX   NCBI_TaxID=39947;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Nipponbare;
RX   PubMed=12791992; DOI=10.1126/science.1083523;
RA   Yu Y., Rambo T., Currie J., Saski C., Kim H.-R., Collura K., Thompson S.,
RA   Simmons J., Yang T.-J., Nah G., Patel A.J., Thurmond S., Henry D.,
RA   Oates R., Palmer M., Pries G., Gibson J., Anderson H., Paradkar M.,
RA   Crane L., Dale J., Carver M.B., Wood T., Frisch D., Engler F.,
RA   Soderlund C., Palmer L.E., Teytelman L., Nascimento L., De la Bastide M.,
RA   Spiegel L., Ware D., O'Shaughnessy A., Dike S., Dedhia N., Preston R.,
RA   Huang E., Ferraro K., Kuit K., Miller B., Zutavern T., Katzenberger F.,
RA   Muller S., Balija V., Martienssen R.A., Stein L., Minx P., Johnson D.,
RA   Cordum H., Mardis E., Cheng Z., Jiang J., Wilson R., McCombie W.R.,
RA   Wing R.A., Yuan Q., Ouyang S., Liu J., Jones K.M., Gansberger K.,
RA   Moffat K., Hill J., Tsitrin T., Overton L., Bera J., Kim M., Jin S.,
RA   Tallon L., Ciecko A., Pai G., Van Aken S., Utterback T., Reidmuller S.,
RA   Bormann J., Feldblyum T., Hsiao J., Zismann V., Blunt S., de Vazeille A.R.,
RA   Shaffer T., Koo H., Suh B., Yang Q., Haas B., Peterson J., Pertea M.,
RA   Volfovsky N., Wortman J., White O., Salzberg S.L., Fraser C.M., Buell C.R.,
RA   Messing J., Song R., Fuks G., Llaca V., Kovchak S., Young S., Bowers J.E.,
RA   Paterson A.H., Johns M.A., Mao L., Pan H., Dean R.A.;
RT   "In-depth view of structure, activity, and evolution of rice chromosome
RT   10.";
RL   Science 300:1566-1569(2003).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Nipponbare;
RX   PubMed=16100779; DOI=10.1038/nature03895;
RG   International rice genome sequencing project (IRGSP);
RT   "The map-based sequence of the rice genome.";
RL   Nature 436:793-800(2005).
RN   [3]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Nipponbare;
RX   PubMed=18089549; DOI=10.1093/nar/gkm978;
RG   The rice annotation project (RAP);
RT   "The rice annotation project database (RAP-DB): 2008 update.";
RL   Nucleic Acids Res. 36:D1028-D1033(2008).
RN   [4]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Nipponbare;
RX   PubMed=24280374; DOI=10.1186/1939-8433-6-4;
RA   Kawahara Y., de la Bastide M., Hamilton J.P., Kanamori H., McCombie W.R.,
RA   Ouyang S., Schwartz D.C., Tanaka T., Wu J., Zhou S., Childs K.L.,
RA   Davidson R.M., Lin H., Quesada-Ocampo L., Vaillancourt B., Sakai H.,
RA   Lee S.S., Kim J., Numa H., Itoh T., Buell C.R., Matsumoto T.;
RT   "Improvement of the Oryza sativa Nipponbare reference genome using next
RT   generation sequence and optical map data.";
RL   Rice 6:4-4(2013).
RN   [5]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2).
RC   STRAIN=cv. Nipponbare;
RX   PubMed=12869764; DOI=10.1126/science.1081288;
RG   The rice full-length cDNA consortium;
RT   "Collection, mapping, and annotation of over 28,000 cDNA clones from
RT   japonica rice.";
RL   Science 301:376-379(2003).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine +
CC         [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-
CC         cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.;
CC         EC=2.3.2.27;
CC   -!- PATHWAY: Protein modification; protein ubiquitination.
CC   -!- ALTERNATIVE PRODUCTS:
CC       Event=Alternative splicing; Named isoforms=2;
CC       Name=1;
CC         IsoId=Q337A0-1; Sequence=Displayed;
CC       Name=2;
CC         IsoId=Q337A0-2; Sequence=VSP_039536, VSP_039537;
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAG13435.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
CC       Sequence=AAM92304.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
CC       Sequence=ABG66196.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
CC       Sequence=BAH94971.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR   EMBL; AC051634; AAG13435.1; ALT_SEQ; Genomic_DNA.
DR   EMBL; AC079029; AAM92304.1; ALT_SEQ; Genomic_DNA.
DR   EMBL; DP000086; ABB47902.2; -; Genomic_DNA.
DR   EMBL; DP000086; ABG66195.1; -; Genomic_DNA.
DR   EMBL; DP000086; ABG66196.1; ALT_SEQ; Genomic_DNA.
DR   EMBL; AP008216; BAH94971.1; ALT_SEQ; Genomic_DNA.
DR   EMBL; AP014966; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AK063580; -; NOT_ANNOTATED_CDS; mRNA.
DR   EMBL; AK065223; BAG89425.1; -; mRNA.
DR   RefSeq; XP_015614443.1; XM_015758957.1. [Q337A0-1]
DR   AlphaFoldDB; Q337A0; -.
DR   SMR; Q337A0; -.
DR   STRING; 4530.OS10T0521600-01; -.
DR   PaxDb; Q337A0; -.
DR   PRIDE; Q337A0; -.
DR   GeneID; 9266159; -.
DR   KEGG; osa:9266159; -.
DR   eggNOG; ENOG502QR1Y; Eukaryota.
DR   HOGENOM; CLU_081178_0_0_1; -.
DR   InParanoid; Q337A0; -.
DR   OrthoDB; 432910at2759; -.
DR   UniPathway; UPA00143; -.
DR   Proteomes; UP000000763; Chromosome 10.
DR   Proteomes; UP000059680; Chromosome 10.
DR   Genevisible; Q337A0; OS.
DR   GO; GO:0005789; C:endoplasmic reticulum membrane; IBA:GO_Central.
DR   GO; GO:0042281; F:dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase activity; IBA:GO_Central.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006490; P:oligosaccharide-lipid intermediate biosynthetic process; IBA:GO_Central.
DR   GO; GO:0006487; P:protein N-linked glycosylation; IBA:GO_Central.
DR   GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
DR   Gene3D; 1.25.40.20; -; 2.
DR   Gene3D; 3.30.40.10; -; 1.
DR   InterPro; IPR002110; Ankyrin_rpt.
DR   InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR   InterPro; IPR001841; Znf_RING.
DR   InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR   InterPro; IPR017907; Znf_RING_CS.
DR   Pfam; PF00023; Ank; 1.
DR   Pfam; PF13637; Ank_4; 2.
DR   SMART; SM00248; ANK; 5.
DR   SUPFAM; SSF48403; SSF48403; 1.
DR   PROSITE; PS50297; ANK_REP_REGION; 1.
DR   PROSITE; PS50088; ANK_REPEAT; 5.
DR   PROSITE; PS00518; ZF_RING_1; 1.
DR   PROSITE; PS50089; ZF_RING_2; 1.
PE   2: Evidence at transcript level;
KW   Alternative splicing; ANK repeat; Metal-binding; Reference proteome;
KW   Repeat; Transferase; Ubl conjugation pathway; Zinc; Zinc-finger.
FT   CHAIN           1..520
FT                   /note="Probable E3 ubiquitin-protein ligase XBOS33"
FT                   /id="PRO_0000395747"
FT   REPEAT          44..73
FT                   /note="ANK 1"
FT   REPEAT          77..106
FT                   /note="ANK 2"
FT   REPEAT          111..140
FT                   /note="ANK 3"
FT   REPEAT          185..214
FT                   /note="ANK 4"
FT   REPEAT          228..258
FT                   /note="ANK 5"
FT   ZN_FING         327..377
FT                   /note="RING-type"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00175"
FT   REGION          467..493
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   VAR_SEQ         311..329
FT                   /note="EFGLLHTVASVDDSDLCAV -> LVLNNSLLTNRFSSDGSKV (in
FT                   isoform 2)"
FT                   /evidence="ECO:0000303|PubMed:12869764"
FT                   /id="VSP_039536"
FT   VAR_SEQ         330..520
FT                   /note="Missing (in isoform 2)"
FT                   /evidence="ECO:0000303|PubMed:12869764"
FT                   /id="VSP_039537"
SQ   SEQUENCE   520 AA;  55562 MW;  8457338484628574 CRC64;
     MGNSLGCSAS GERLVSAARD GDAVEARMLL ELSPALARYS TFGGLNSPLH FAAAKGHLDI
     VTLLLEKGAD VNVRNYCGQT ALMHACRHGH WEVVQMLLLF RCNVTRADYL SGRTALHFAA
     HDGLVRCVRL LLADFVPSAP LEDGASSTVD GGECQTNSGS SPCSSLGLKF NESARLRYIN
     KPADGGVTAL HMAALNGHFD CMQLLIDLGA NVSAVTFPYG TTANLIGAGS TPLHYAAGGG
     NAECCQLLLS KGASKLTLNC NGWLPIDVAR MFGRRFLEPL LSPNSNSSIP AYQPSNYLAL
     PFMSILNIAR EFGLLHTVAS VDDSDLCAVC LERSCSVAAE GCCHEFCIKC ALYLCSTSNT
     RVEFTGPPGS IPCPLCRNGI MSFTKLPSTP TEGLKSSSAL TFCNPCMLNT RSVDSPATIS
     KAEIRRNRVA AVSSELVCPL TCSPFPSSAL PTCRCSDDDP CDAIETQDGS EVQSPQPSHC
     ASMEMDKREQ QDLDRTSCSG MFWSRRSCHR EEQCNAEINA