XCORE_HBVC4
ID XCORE_HBVC4 Reviewed; 359 AA.
AC Q67863;
DT 18-MAR-2008, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1996, sequence version 1.
DT 23-FEB-2022, entry version 76.
DE RecName: Full=Putative X-Core fused protein;
OS Hepatitis B virus genotype C subtype adr (isolate Korea/Kim/1989) (HBV-C).
OC Viruses; Riboviria; Pararnavirae; Artverviricota; Revtraviricetes;
OC Blubervirales; Hepadnaviridae; Orthohepadnavirus.
OX NCBI_TaxID=31512;
OH NCBI_TaxID=9606; Homo sapiens (Human).
OH NCBI_TaxID=9598; Pan troglodytes (Chimpanzee).
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC RNA].
RX PubMed=2928116; DOI=10.1093/nar/17.5.2124;
RA Rho H.M., Kim K., Hyun S.W., Kim Y.S.;
RT "The nucleotide sequence and reading frames of a mutant hepatitis B virus
RT subtype adr.";
RL Nucleic Acids Res. 17:2124-2124(1989).
CC -!- ALTERNATIVE PRODUCTS:
CC Event=Alternative initiation; Named isoforms=2;
CC Name=X-Core fused protein;
CC IsoId=Q67863-1; Sequence=Displayed;
CC Name=Capsid protein;
CC IsoId=P0C6H6-1; Sequence=External;
CC -!- CAUTION: One nucleotide addition (T) at position 1821 changed the
CC reading frame of the known B gene by erasing the stop codon and
CC consequently fusing the B gene with C gene. {ECO:0000305}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; X14193; CAA32402.1; -; Genomic_DNA.
DR PIR; S04570; S04570.
DR SMR; Q67863; -.
DR Proteomes; UP000007924; Genome.
DR GO; GO:0033650; C:host cell mitochondrion; IEA:UniProtKB-UniRule.
DR GO; GO:0042025; C:host cell nucleus; IEA:UniProtKB-UniRule.
DR GO; GO:0039619; C:T=4 icosahedral viral capsid; IEA:UniProtKB-UniRule.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0005198; F:structural molecule activity; IEA:UniProtKB-UniRule.
DR GO; GO:0039652; P:induction by virus of host NF-kappaB cascade; IEA:UniProtKB-UniRule.
DR GO; GO:0075521; P:microtubule-dependent intracellular transport of viral material towards nucleus; IEA:UniProtKB-UniRule.
DR GO; GO:0039592; P:suppression by virus of G2/M transition of host mitotic cell cycle; IEA:UniProtKB-UniRule.
DR GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-UniRule.
DR GO; GO:0046718; P:viral entry into host cell; IEA:UniProtKB-UniRule.
DR GO; GO:0019079; P:viral genome replication; IEA:UniProtKB-UniRule.
DR GO; GO:0075732; P:viral penetration into host nucleus; IEA:UniProtKB-UniRule.
DR Gene3D; 1.10.4090.10; -; 1.
DR HAMAP; MF_04076; HBV_HBEAG; 1.
DR HAMAP; MF_04074; HBV_X; 1.
DR InterPro; IPR013195; Hepatitis_B_virus_capsid_N.
DR InterPro; IPR002006; Hepatitis_core.
DR InterPro; IPR000236; Transactivation_prot_X.
DR InterPro; IPR036459; Viral_capsid_core_dom_sf_HBV.
DR Pfam; PF08290; Hep_core_N; 1.
DR Pfam; PF00906; Hepatitis_core; 2.
DR Pfam; PF00739; X; 1.
DR SUPFAM; SSF47852; SSF47852; 1.
PE 3: Inferred from homology;
KW Alternative initiation.
FT CHAIN 1..359
FT /note="Putative X-Core fused protein"
FT /id="PRO_0000324752"
FT REGION 25..48
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 312..359
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 328..348
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 359 AA; 40201 MW; 046D7B6E12F368B0 CRC64;
MAARVCCQLD PARDVLCLRP VGAESRGRPV SRPFGPHPSP SSSAVPADHG AHLSLRGLPV
CAFSSAGPCA LRFTSARRME TTVNADQVLP KVLHKRTLGL SAMSTSDLEA YFKDCLFKDW
EDLGEEIRLM IFVLGGCRHK LVCSPAPCNF FHLCLIISCS CPTVHASKLC LGWLWGMDID
PYKEFGASVE LLSFLPSDFF PSIRDLLDTA SALYREALES PEHCSPHHTA LRQAILCWGE
LMNLATWVGS NLEDPASREL VVSYVNVNMG LKIRQLLWFH ISCLTFGRET VLEYLVSFGV
WIRTPPAYRP PNAPILSTLP ETTVVRRRGR SPRRRTPSPR RRRSESPRRR RSQSRESQC
