ID   XERCL_CALS4             Reviewed;         391 AA.
AC   Q8R890;
DT   22-AUG-2003, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2002, sequence version 1.
DT   25-MAY-2022, entry version 103.
DE   RecName: Full=Tyrosine recombinase XerC-like {ECO:0000305};
GN   OrderedLocusNames=TTE2127;
OS   Caldanaerobacter subterraneus subsp. tengcongensis (strain DSM 15242 / JCM
OS   11007 / NBRC 100824 / MB4) (Thermoanaerobacter tengcongensis).
OC   Bacteria; Firmicutes; Clostridia; Thermoanaerobacterales;
OC   Thermoanaerobacteraceae; Caldanaerobacter.
OX   NCBI_TaxID=273068;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 15242 / JCM 11007 / NBRC 100824 / MB4;
RX   PubMed=11997336; DOI=10.1101/gr.219302;
RA   Bao Q., Tian Y., Li W., Xu Z., Xuan Z., Hu S., Dong W., Yang J., Chen Y.,
RA   Xue Y., Xu Y., Lai X., Huang L., Dong X., Ma Y., Ling L., Tan H., Chen R.,
RA   Wang J., Yu J., Yang H.;
RT   "A complete sequence of the T. tengcongensis genome.";
RL   Genome Res. 12:689-700(2002).
CC   -!- FUNCTION: Site-specific tyrosine recombinase, which acts by catalyzing
CC       the cutting and rejoining of the recombining DNA molecules.
CC       {ECO:0000250|UniProtKB:P0A8P8}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000305}.
CC   -!- MISCELLANEOUS: In contrast to other XerC proteins, it has a much longer
CC       N-terminal part. {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the 'phage' integrase family. {ECO:0000305}.
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DR   EMBL; AE008691; AAM25292.1; -; Genomic_DNA.
DR   RefSeq; WP_011026230.1; NC_003869.1.
DR   AlphaFoldDB; Q8R890; -.
DR   SMR; Q8R890; -.
DR   STRING; 273068.TTE2127; -.
DR   EnsemblBacteria; AAM25292; AAM25292; TTE2127.
DR   KEGG; tte:TTE2127; -.
DR   eggNOG; COG0582; Bacteria.
DR   HOGENOM; CLU_027562_17_1_9; -.
DR   OMA; LRASVCY; -.
DR   OrthoDB; 785253at2; -.
DR   Proteomes; UP000000555; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR   GO; GO:0007059; P:chromosome segregation; IEA:UniProtKB-KW.
DR   GO; GO:0015074; P:DNA integration; IEA:UniProtKB-KW.
DR   GO; GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.
DR   Gene3D; 1.10.150.130; -; 1.
DR   Gene3D; 1.10.443.10; -; 1.
DR   InterPro; IPR044068; CB.
DR   InterPro; IPR011010; DNA_brk_join_enz.
DR   InterPro; IPR013762; Integrase-like_cat_sf.
DR   InterPro; IPR002104; Integrase_catalytic.
DR   InterPro; IPR010998; Integrase_recombinase_N.
DR   InterPro; IPR004107; Integrase_SAM-like_N.
DR   Pfam; PF14659; Phage_int_SAM_3; 1.
DR   Pfam; PF00589; Phage_integrase; 1.
DR   SUPFAM; SSF56349; SSF56349; 1.
DR   PROSITE; PS51900; CB; 1.
DR   PROSITE; PS51898; TYR_RECOMBINASE; 1.
PE   3: Inferred from homology;
KW   Cell cycle; Cell division; Chromosome partition; Cytoplasm;
KW   DNA integration; DNA recombination; DNA-binding; Reference proteome.
FT   CHAIN           1..391
FT                   /note="Tyrosine recombinase XerC-like"
FT                   /id="PRO_0000095353"
FT   DOMAIN          64..148
FT                   /note="Core-binding (CB)"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01248"
FT   DOMAIN          175..384
FT                   /note="Tyr recombinase"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01246"
FT   ACT_SITE        210
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01246"
FT   ACT_SITE        244
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01246"
FT   ACT_SITE        335
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01246"
FT   ACT_SITE        338
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01246"
FT   ACT_SITE        361
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01246"
FT   ACT_SITE        371
FT                   /note="O-(3'-phospho-DNA)-tyrosine intermediate"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01246"
SQ   SEQUENCE   391 AA;  45309 MW;  8593AA098E6C655B CRC64;
     MAKKTNYVKN GKEYYRVTVT IGRDENGKLI RKEFYGKTKK EAEAKKEEYL NGIRNGLNVD
     FQDVTLGDLM HTWLFEVVRM SRKPATFVKY EGHYRNYIKN SELYGMKISI IKSIQIQRYY
     NKLYQQGKSS KTIKALNNFL KTFFNYAVDE GYLAKNPCTG KKIVIPGTPE EKIETEIETF
     SDEEIKKIKE ALKGHRLKAL FLLAFGTGLR QGELLGLKWT DIDFEKKELR VQRMIKQVTI
     IDEKGNRKYK TIEQIPKTKN SIRTVPIPSS LIPMLKEHRN RQREEKLKAG SVYLNDVEKG
     YVFTTELGNT IDASNLLKTY KKILNRAGVP YRKFHAIRHT YATKLFERGV PLKTVSELLG
     HSNISITANI YTHVIPKQKT NAVETLNDLF I