ID   CAO1B_XENLA             Reviewed;         547 AA.
AC   Q6DD09;
DT   23-OCT-2007, integrated into UniProtKB/Swiss-Prot.
DT   16-AUG-2004, sequence version 1.
DT   03-AUG-2022, entry version 45.
DE   RecName: Full=Calcium-binding and coiled-coil domain-containing protein 1-B;
GN   Name=calcoco1-b;
OS   Xenopus laevis (African clawed frog).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus.
OX   NCBI_TaxID=8355;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Embryo;
RG   NIH - Xenopus Gene Collection (XGC) project;
RL   Submitted (JUL-2004) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: May function as a coactivator for aryl hydrocarbon and
CC       nuclear receptors. {ECO:0000250|UniProtKB:Q8CGU1}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250|UniProtKB:Q9DEX1}. Nucleus
CC       {ECO:0000250|UniProtKB:Q9DEX1}. Note=Detected in the cytoplasm at
CC       stages I- II. Detected in the nucleus and the cytoplasm, except for the
CC       germ plasm, of almost all cells in cleaving embryos (By similarity).
CC       {ECO:0000250|UniProtKB:Q9DEX1}.
CC   -!- SIMILARITY: Belongs to the CALCOCO family. {ECO:0000305}.
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DR   EMBL; BC077823; AAH77823.1; -; mRNA.
DR   RefSeq; NP_001086958.1; NM_001093489.1.
DR   AlphaFoldDB; Q6DD09; -.
DR   SMR; Q6DD09; -.
DR   GeneID; 446793; -.
DR   KEGG; xla:446793; -.
DR   CTD; 446793; -.
DR   Xenbase; XB-GENE-1189632; calcoco1.L.
DR   OMA; GLCEHGD; -.
DR   OrthoDB; 179838at2759; -.
DR   Proteomes; UP000186698; Chromosome 2L.
DR   Bgee; 446793; Expressed in internal ear and 6 other tissues.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   InterPro; IPR012852; CALCOCO1-like.
DR   InterPro; IPR041611; SKICH.
DR   Pfam; PF07888; CALCOCO1; 2.
DR   Pfam; PF17751; SKICH; 1.
PE   2: Evidence at transcript level;
KW   Coiled coil; Cytoplasm; Nucleus; Reference proteome.
FT   CHAIN           1..547
FT                   /note="Calcium-binding and coiled-coil domain-containing
FT                   protein 1-B"
FT                   /id="PRO_0000308905"
FT   REGION          473..498
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          143..305
FT                   /evidence="ECO:0000255"
FT   COILED          356..469
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   547 AA;  63035 MW;  09050E887B940B8B CRC64;
     MESISQLQPP MGVNFLNIAP TYIPNTKVEC HYTTPFGMKR STRDWIGIFK VDTSSIRDYE
     TFVWAVPPES SGERSVSHCS VQFQAYYLPR PGEQQYHFRY VDQYGSVRGC SDAFVFGEPR
     PMEELVTLED EDSCMDMLLV VPKATFLQNQ LEMAQQERND LMRARLALEE EVILKEKRIN
     HLEATLETSE KSCFSLKEQC QDLVMREQLA IEEQSLLSCQ EAELRERILQ LQGEIKIMNK
     KMQEKDRELE GTVAIKLSLE NKKVVLKQHL AETTVEIKRY QLQVDSLREK LRSTQDMLSA
     SQQKALLMGE ELAAISSIRD RTISDLHKSR LETADLAIKV SDLSVKYKEG MGQWWQEKTA
     LNHSMEAKRD QIVNLKAEKL SLENSLQAER SQRQALQCKL NQETDARQVQ LSENRRQLSE
     LKSALKVAQM EKQQLREERQ GILQYARSLE ERLDKLADEL WKEDKMLMEE ITDLNPPTLP
     VDHSDSDDES PGDERVSQQL EACSLDEQDL TINLPGFPCE LYKVVINQPA PIACQLQPLP
     EDNSDSW