ID   XERD_SELRU              Reviewed;         341 AA.
AC   O50655;
DT   27-MAY-2002, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-1998, sequence version 1.
DT   25-MAY-2022, entry version 72.
DE   RecName: Full=Integrase/recombinase xerD homolog;
GN   Name=xerD;
OS   Selenomonas ruminantium.
OC   Bacteria; Firmicutes; Negativicutes; Selenomonadales; Selenomonadaceae;
OC   Selenomonas.
OX   NCBI_TaxID=971;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=Subsp. lactilytica;
RX   PubMed=11073919; DOI=10.1128/jb.182.23.6732-6741.2000;
RA   Takatsuka Y., Yamaguchi Y., Ono M., Kamio Y.;
RT   "Gene cloning and molecular characterization of lysine decarboxylase from
RT   Selenomonas ruminantium delineate its evolutionary relationship to
RT   ornithine decarboxylases from eukaryotes.";
RL   J. Bacteriol. 182:6732-6741(2000).
CC   -!- SIMILARITY: Belongs to the 'phage' integrase family. {ECO:0000305}.
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DR   EMBL; AB011029; BAA24921.1; -; Genomic_DNA.
DR   AlphaFoldDB; O50655; -.
DR   SMR; O50655; -.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0015074; P:DNA integration; IEA:UniProtKB-KW.
DR   GO; GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.
DR   GO; GO:0075713; P:establishment of integrated proviral latency; IEA:UniProtKB-KW.
DR   GO; GO:0046718; P:viral entry into host cell; IEA:UniProtKB-KW.
DR   GO; GO:0044826; P:viral genome integration into host DNA; IEA:UniProtKB-KW.
DR   Gene3D; 1.10.150.130; -; 1.
DR   Gene3D; 1.10.443.10; -; 1.
DR   InterPro; IPR044068; CB.
DR   InterPro; IPR011010; DNA_brk_join_enz.
DR   InterPro; IPR013762; Integrase-like_cat_sf.
DR   InterPro; IPR002104; Integrase_catalytic.
DR   InterPro; IPR010998; Integrase_recombinase_N.
DR   Pfam; PF00589; Phage_integrase; 1.
DR   SUPFAM; SSF56349; SSF56349; 1.
DR   PROSITE; PS51900; CB; 1.
DR   PROSITE; PS51898; TYR_RECOMBINASE; 1.
PE   3: Inferred from homology;
KW   DNA integration; DNA recombination; DNA-binding; Viral genome integration;
KW   Virus entry into host cell.
FT   CHAIN           1..341
FT                   /note="Integrase/recombinase xerD homolog"
FT                   /id="PRO_0000197546"
FT   DOMAIN          21..111
FT                   /note="Core-binding (CB)"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01248"
FT   DOMAIN          140..336
FT                   /note="Tyr recombinase"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01246"
FT   ACT_SITE        180
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01246"
FT   ACT_SITE        207
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01246"
FT   ACT_SITE        288
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01246"
FT   ACT_SITE        291
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01246"
FT   ACT_SITE        314
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01246"
FT   ACT_SITE        323
FT                   /note="O-(3'-phospho-DNA)-tyrosine intermediate"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01246"
SQ   SEQUENCE   341 AA;  38721 MW;  12605EBD3CE9C3F0 CRC64;
     MLLYILLIES RFIMKIKDNF MLIKNARIEN NERLSLKAKR RLEKSKADNT LKAYACDWSD
     FSDWCQYHGV TDLPASPETI VNYINDLADD AKANTVSRRV TAISENHIAA GFSGRHNPAK
     DGMVRAAMSA IRREKGTFQR GKSPILMETL YLLADLFDEE KLSGLRDKAL IYLGFAGAFR
     RSELVHIQYE DLTFTPQGVI IFMAHSKGDQ LGHGEQIAIP YAPQAEICAV RALKKWLDTA
     QIHRGPIFRP ITRVQSLRNT QLSDKSVALI VKKYVGLAGL DEHLFAGHSL RRGFATSAAQ
     HDIDALTIMR QTRHKSEKMV HRYIEQGNIF KDNALNRMYN K