XER_PSESX
ID XER_PSESX Reviewed; 473 AA.
AC Q8KRZ2;
DT 22-AUG-2003, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-2002, sequence version 1.
DT 03-AUG-2022, entry version 72.
DE RecName: Full=Putative tyrosine recombinase XerC {ECO:0000305};
GN Name=xerC {ECO:0000312|EMBL:AAM77365.1};
OS Pseudomonas syringae.
OC Bacteria; Proteobacteria; Gammaproteobacteria; Pseudomonadales;
OC Pseudomonadaceae; Pseudomonas.
OX NCBI_TaxID=317;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=BR2R;
RA Kinscherf T.G., Willis D.K.;
RT "Sequence analysis of the tabtoxin biosynthetic region.";
RL Submitted (JUN-2002) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Site-specific tyrosine recombinase, which acts by catalyzing
CC the cutting and rejoining of the recombining DNA molecules.
CC {ECO:0000250|UniProtKB:P0A8P8}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000305}.
CC -!- MISCELLANEOUS: In contrast to other XerC proteins, it has a much longer
CC C-terminal part. {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the 'phage' integrase family. {ECO:0000305}.
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DR EMBL; AF521605; AAM77365.1; -; Genomic_DNA.
DR AlphaFoldDB; Q8KRZ2; -.
DR SMR; Q8KRZ2; -.
DR PRIDE; Q8KRZ2; -.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR GO; GO:0007059; P:chromosome segregation; IEA:UniProtKB-KW.
DR GO; GO:0015074; P:DNA integration; IEA:UniProtKB-KW.
DR GO; GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.
DR Gene3D; 1.10.150.130; -; 1.
DR Gene3D; 1.10.443.10; -; 1.
DR InterPro; IPR044068; CB.
DR InterPro; IPR011010; DNA_brk_join_enz.
DR InterPro; IPR013762; Integrase-like_cat_sf.
DR InterPro; IPR002104; Integrase_catalytic.
DR InterPro; IPR010998; Integrase_recombinase_N.
DR Pfam; PF00589; Phage_integrase; 1.
DR SUPFAM; SSF56349; SSF56349; 1.
DR PROSITE; PS51900; CB; 1.
DR PROSITE; PS51898; TYR_RECOMBINASE; 1.
PE 3: Inferred from homology;
KW Cell cycle; Cell division; Chromosome partition; Cytoplasm;
KW DNA integration; DNA recombination; DNA-binding.
FT CHAIN 1..473
FT /note="Putative tyrosine recombinase XerC"
FT /id="PRO_0000095317"
FT DOMAIN 4..82
FT /note="Core-binding (CB)"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01248"
FT DOMAIN 118..305
FT /note="Tyr recombinase"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01246"
FT REGION 341..365
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT ACT_SITE 156
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01246"
FT ACT_SITE 183
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01246"
FT ACT_SITE 256
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01246"
FT ACT_SITE 259
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01246"
FT ACT_SITE 283
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01246"
FT ACT_SITE 292
FT /note="O-(3'-phospho-DNA)-tyrosine intermediate"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01246"
SQ SEQUENCE 473 AA; 53949 MW; 80DDF2221D20180D CRC64;
MKPMTLPELT QEYILTHDLR PDTVKIYRAA TKAYVNFFGE CLACETTHRD MLEWRRSELA
RISKRSWNTY SSHLRTVYRY AMEHGLVELK VNPLKDTRVM PTKRPKKTIG NDVIVRARNW
LRFLVQEELS TGKRSEITPA WFWLAVFETF YYTGIRLNAL LCLRYENVDL GQRLIRVRGE
TEKTHREFMI PIPDGLMPHL VLVMDTAKKV GFSGTDQVFN INRFSGHYKR EYMNSDQVEA
MYKKLTNMTG TRMTPHRFRH TIASELMRQP ERNIHITKNL LNHSNIATTM EYIEPDYDLM
REVMNERGQQ QAKINYLVRP IIPKSSGPAA GSAVPRVSLV SGTELQPATT ESSEAKKADD
TASNPPVAER LELMSTAPLV NVLKSTPVSV HSEPVTSNEA KAQALSLISD APETEYEFGE
LEDIARWIRE NAAGEMVVQI AAEEDIGTIS EGKASIQSPD GYYRIPWSSG SVK