ID   XER_SYNE7               Reviewed;         320 AA.
AC   Q8KUV2; Q31JS7;
DT   22-AUG-2003, integrated into UniProtKB/Swiss-Prot.
DT   16-AUG-2004, sequence version 2.
DT   03-AUG-2022, entry version 119.
DE   RecName: Full=Tyrosine recombinase Synpcc7942_B2651 {ECO:0000305};
GN   OrderedLocusNames=Synpcc7942_B2651; ORFNames=pANL28, sex3028;
OS   Synechococcus elongatus (strain PCC 7942 / FACHB-805) (Anacystis nidulans
OS   R2).
OG   Plasmid pANL.
OC   Bacteria; Cyanobacteria; Synechococcales; Synechococcaceae; Synechococcus.
OX   NCBI_TaxID=1140;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=PCC 7942 / FACHB-805; PLASMID=pANL;
RA   Holtman C.K., Chen Y., Sandoval P., Socias T., Mohler B.J., Youderian P.,
RA   Golden S.S.;
RT   "pANL, the large plasmid of Synechococcus elongatus PCC 7942.";
RL   Submitted (MAY-2004) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=PCC 7942 / FACHB-805; PLASMID=pANL;
RG   US DOE Joint Genome Institute;
RA   Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T.,
RA   Hammon N., Israni S., Pitluck S., Schmutz J., Larimer F., Land M.,
RA   Kyrpides N., Lykidis A., Richardson P.;
RT   "Complete sequence of plasmid 1 of Synechococcus elongatus PCC 7942.";
RL   Submitted (AUG-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Site-specific tyrosine recombinase, which acts by catalyzing
CC       the cutting and rejoining of the recombining DNA molecules.
CC       {ECO:0000250|UniProtKB:P0A8P8}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the 'phage' integrase family. {ECO:0000305}.
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DR   EMBL; AF441790; AAM81156.2; -; Genomic_DNA.
DR   EMBL; CP000101; ABB58680.1; -; Genomic_DNA.
DR   RefSeq; NP_665769.2; NC_004073.2.
DR   RefSeq; WP_011055144.1; NC_007595.1.
DR   AlphaFoldDB; Q8KUV2; -.
DR   SMR; Q8KUV2; -.
DR   PRIDE; Q8KUV2; -.
DR   EnsemblBacteria; ABB58680; ABB58680; Synpcc7942_B2651.
DR   KEGG; syf:Synpcc7942_B2651; -.
DR   eggNOG; COG0582; Bacteria.
DR   HOGENOM; CLU_027562_9_6_3; -.
DR   OMA; HNLDRDP; -.
DR   OrthoDB; 745068at2; -.
DR   BioCyc; SYNEL:SYNPCC7942_B2651-MON; -.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR   GO; GO:0007059; P:chromosome segregation; IEA:UniProtKB-KW.
DR   GO; GO:0015074; P:DNA integration; IEA:UniProtKB-KW.
DR   GO; GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.
DR   Gene3D; 1.10.150.130; -; 1.
DR   Gene3D; 1.10.443.10; -; 1.
DR   InterPro; IPR044068; CB.
DR   InterPro; IPR011010; DNA_brk_join_enz.
DR   InterPro; IPR013762; Integrase-like_cat_sf.
DR   InterPro; IPR002104; Integrase_catalytic.
DR   InterPro; IPR010998; Integrase_recombinase_N.
DR   InterPro; IPR004107; Integrase_SAM-like_N.
DR   Pfam; PF02899; Phage_int_SAM_1; 1.
DR   Pfam; PF00589; Phage_integrase; 1.
DR   SUPFAM; SSF56349; SSF56349; 1.
DR   PROSITE; PS51900; CB; 1.
DR   PROSITE; PS51898; TYR_RECOMBINASE; 1.
PE   3: Inferred from homology;
KW   Cell cycle; Cell division; Chromosome partition; Cytoplasm;
KW   DNA integration; DNA recombination; DNA-binding; Plasmid.
FT   CHAIN           1..320
FT                   /note="Tyrosine recombinase Synpcc7942_B2651"
FT                   /id="PRO_0000095340"
FT   DOMAIN          16..106
FT                   /note="Core-binding (CB)"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01248"
FT   DOMAIN          127..313
FT                   /note="Tyr recombinase"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01246"
FT   ACT_SITE        167
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01246"
FT   ACT_SITE        193
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01246"
FT   ACT_SITE        264
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01246"
FT   ACT_SITE        267
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01246"
FT   ACT_SITE        291
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01246"
FT   ACT_SITE        300
FT                   /note="O-(3'-phospho-DNA)-tyrosine intermediate"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01246"
SQ   SEQUENCE   320 AA;  36950 MW;  E30C9E8EF1CB02DC CRC64;
     MTEAIAVVES RAIAPVQDWD VLQMLLEDHR SPNTRRAYDR DLRLFFAWWL DEDPHPEAIA
     YWLSLPQSEA IAVVLRWKAS MRDRGLAEAT INRRLAALKS LVRFSRRLGR CTFSLEDVKG
     DRVQSYRDTT GTTPERFREL LALPNRQTAK GARDYAILRL LWENALRRSE AVQTRVQDLE
     QGDRRLWILG KGKGRQRLPV SLSVEMVQAL QDWLRWHPKA EPEQPLFTAL DRRSYGQQLS
     DQAVYLLVKR SAEAIKLGKR LSPHRIRHSA ITAALDATGG NIRLVQKLSR HSRLETLQRY
     DDARQDFQGE CTEHLAKLLG