ID   XER_SYNY3               Reviewed;         313 AA.
AC   P72680;
DT   22-AUG-2003, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-1997, sequence version 1.
DT   25-MAY-2022, entry version 132.
DE   RecName: Full=Tyrosine recombinase slr0733 {ECO:0000305};
GN   Name=xerC {ECO:0000312|EMBL:BAA16682.1}; OrderedLocusNames=slr0733;
OS   Synechocystis sp. (strain PCC 6803 / Kazusa).
OC   Bacteria; Cyanobacteria; Synechococcales; Merismopediaceae; Synechocystis;
OC   unclassified Synechocystis.
OX   NCBI_TaxID=1111708;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=PCC 6803 / Kazusa;
RX   PubMed=8905231; DOI=10.1093/dnares/3.3.109;
RA   Kaneko T., Sato S., Kotani H., Tanaka A., Asamizu E., Nakamura Y.,
RA   Miyajima N., Hirosawa M., Sugiura M., Sasamoto S., Kimura T., Hosouchi T.,
RA   Matsuno A., Muraki A., Nakazaki N., Naruo K., Okumura S., Shimpo S.,
RA   Takeuchi C., Wada T., Watanabe A., Yamada M., Yasuda M., Tabata S.;
RT   "Sequence analysis of the genome of the unicellular cyanobacterium
RT   Synechocystis sp. strain PCC6803. II. Sequence determination of the entire
RT   genome and assignment of potential protein-coding regions.";
RL   DNA Res. 3:109-136(1996).
CC   -!- FUNCTION: Site-specific tyrosine recombinase, which acts by catalyzing
CC       the cutting and rejoining of the recombining DNA molecules.
CC       {ECO:0000250|UniProtKB:P0A8P8}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the 'phage' integrase family. {ECO:0000305}.
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DR   EMBL; BA000022; BAA16682.1; -; Genomic_DNA.
DR   PIR; S74530; S74530.
DR   AlphaFoldDB; P72680; -.
DR   SMR; P72680; -.
DR   DIP; DIP-48817N; -.
DR   IntAct; P72680; 21.
DR   STRING; 1148.1651754; -.
DR   PaxDb; P72680; -.
DR   PRIDE; P72680; -.
DR   EnsemblBacteria; BAA16682; BAA16682; BAA16682.
DR   KEGG; syn:slr0733; -.
DR   eggNOG; COG0582; Bacteria.
DR   InParanoid; P72680; -.
DR   OMA; HNLDRDP; -.
DR   PhylomeDB; P72680; -.
DR   Proteomes; UP000001425; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR   GO; GO:0007059; P:chromosome segregation; IEA:UniProtKB-KW.
DR   GO; GO:0015074; P:DNA integration; IEA:UniProtKB-KW.
DR   GO; GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.
DR   Gene3D; 1.10.150.130; -; 1.
DR   Gene3D; 1.10.443.10; -; 1.
DR   InterPro; IPR044068; CB.
DR   InterPro; IPR011010; DNA_brk_join_enz.
DR   InterPro; IPR013762; Integrase-like_cat_sf.
DR   InterPro; IPR002104; Integrase_catalytic.
DR   InterPro; IPR010998; Integrase_recombinase_N.
DR   InterPro; IPR004107; Integrase_SAM-like_N.
DR   Pfam; PF02899; Phage_int_SAM_1; 1.
DR   Pfam; PF00589; Phage_integrase; 1.
DR   SUPFAM; SSF56349; SSF56349; 1.
DR   PROSITE; PS51900; CB; 1.
DR   PROSITE; PS51898; TYR_RECOMBINASE; 1.
PE   3: Inferred from homology;
KW   Cell cycle; Cell division; Chromosome partition; Cytoplasm;
KW   DNA integration; DNA recombination; DNA-binding; Reference proteome.
FT   CHAIN           1..313
FT                   /note="Tyrosine recombinase slr0733"
FT                   /id="PRO_0000095341"
FT   DOMAIN          7..101
FT                   /note="Core-binding (CB)"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01248"
FT   DOMAIN          122..307
FT                   /note="Tyr recombinase"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01246"
FT   ACT_SITE        162
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01246"
FT   ACT_SITE        188
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01246"
FT   ACT_SITE        258
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01246"
FT   ACT_SITE        261
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01246"
FT   ACT_SITE        285
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01246"
FT   ACT_SITE        294
FT                   /note="O-(3'-phospho-DNA)-tyrosine intermediate"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01246"
SQ   SEQUENCE   313 AA;  35095 MW;  BC40C9A256EA000C CRC64;
     MFLPSPNNLS GLNQNILEEL LRDKRSPNTR RTYAKALKDF FLTMAGEEPS PDVIAWFLSL
     DHFQAIAMVL RYRAELLAKD LKPATINVRL AAIKSLVNYA RRVGKCQYTL EDVEGLKAET
     YRDTTGVSPT SFKQITDHIT PDSLKGKRDL AIMRLLWDNA LRRAEVCGLN VGDYQPTERQ
     LLIKGKGKLG KQAITLSAKG MALINQWLTA IGPRPKNEPL FCTLDRATFG HRLSGNAIYN
     LVRTSAESAG IHKVMSPHRV RHSAITAALE ATNGDTRKVQ KLSRHSNLNT LMIYDDNRHQ
     HQAQITDILA DLL