ID   CAP18_ARATH             Reviewed;         295 AA.
AC   Q9FKQ2;
DT   13-APR-2004, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2001, sequence version 1.
DT   03-AUG-2022, entry version 105.
DE   RecName: Full=Putative clathrin assembly protein At5g65370;
GN   OrderedLocusNames=At5g65370; ORFNames=MNA5.10;
OS   Arabidopsis thaliana (Mouse-ear cress).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX   NCBI_TaxID=3702;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=9679202; DOI=10.1093/dnares/5.2.131;
RA   Kaneko T., Kotani H., Nakamura Y., Sato S., Asamizu E., Miyajima N.,
RA   Tabata S.;
RT   "Structural analysis of Arabidopsis thaliana chromosome 5. V. Sequence
RT   features of the regions of 1,381,565 bp covered by twenty one physically
RT   assigned P1 and TAC clones.";
RL   DNA Res. 5:131-145(1998).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Columbia;
RX   PubMed=27862469; DOI=10.1111/tpj.13415;
RA   Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA   Town C.D.;
RT   "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT   genome.";
RL   Plant J. 89:789-804(2017).
CC   -!- SUBCELLULAR LOCATION: Membrane, clathrin-coated pit {ECO:0000250}.
CC       Golgi apparatus {ECO:0000250}. Cytoplasmic vesicle, clathrin-coated
CC       vesicle {ECO:0000250}. Note=Colocalized with clathrin in the Golgi
CC       area. {ECO:0000250}.
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DR   EMBL; AB011479; BAB11559.1; -; Genomic_DNA.
DR   EMBL; CP002688; AED98044.1; -; Genomic_DNA.
DR   RefSeq; NP_201340.1; NM_125935.1.
DR   AlphaFoldDB; Q9FKQ2; -.
DR   SMR; Q9FKQ2; -.
DR   STRING; 3702.AT5G65370.1; -.
DR   PaxDb; Q9FKQ2; -.
DR   PRIDE; Q9FKQ2; -.
DR   EnsemblPlants; AT5G65370.1; AT5G65370.1; AT5G65370.
DR   GeneID; 836662; -.
DR   Gramene; AT5G65370.1; AT5G65370.1; AT5G65370.
DR   KEGG; ath:AT5G65370; -.
DR   Araport; AT5G65370; -.
DR   TAIR; locus:2168287; AT5G65370.
DR   eggNOG; KOG0251; Eukaryota.
DR   HOGENOM; CLU_073451_0_0_1; -.
DR   InParanoid; Q9FKQ2; -.
DR   OMA; LDCYLSI; -.
DR   OrthoDB; 902843at2759; -.
DR   PhylomeDB; Q9FKQ2; -.
DR   PRO; PR:Q9FKQ2; -.
DR   Proteomes; UP000006548; Chromosome 5.
DR   ExpressionAtlas; Q9FKQ2; baseline and differential.
DR   Genevisible; Q9FKQ2; AT.
DR   GO; GO:0005905; C:clathrin-coated pit; IBA:GO_Central.
DR   GO; GO:0030136; C:clathrin-coated vesicle; IBA:GO_Central.
DR   GO; GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.
DR   GO; GO:0005545; F:1-phosphatidylinositol binding; IBA:GO_Central.
DR   GO; GO:0032050; F:clathrin heavy chain binding; IBA:GO_Central.
DR   GO; GO:0005546; F:phosphatidylinositol-4,5-bisphosphate binding; IBA:GO_Central.
DR   GO; GO:0000149; F:SNARE binding; IBA:GO_Central.
DR   GO; GO:0048268; P:clathrin coat assembly; IEA:InterPro.
DR   GO; GO:0072583; P:clathrin-dependent endocytosis; IBA:GO_Central.
DR   GO; GO:0006900; P:vesicle budding from membrane; IBA:GO_Central.
DR   Gene3D; 1.25.40.90; -; 1.
DR   InterPro; IPR011417; ANTH_dom.
DR   InterPro; IPR045192; AP180-like.
DR   InterPro; IPR013809; ENTH.
DR   InterPro; IPR008942; ENTH_VHS.
DR   PANTHER; PTHR22951; PTHR22951; 1.
DR   Pfam; PF07651; ANTH; 1.
DR   SUPFAM; SSF48464; SSF48464; 1.
DR   PROSITE; PS50942; ENTH; 1.
PE   3: Inferred from homology;
KW   Coated pit; Cytoplasmic vesicle; Endocytosis; Golgi apparatus; Membrane;
KW   Reference proteome.
FT   CHAIN           1..295
FT                   /note="Putative clathrin assembly protein At5g65370"
FT                   /id="PRO_0000187084"
FT   DOMAIN          26..169
FT                   /note="ENTH"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00243"
SQ   SEQUENCE   295 AA;  33872 MW;  7CC9A2B95A340A77 CRC64;
     MGKLATLNGI LKDEASQMKL NVVHLCSSVN AKTIDLALLK ATSHTSNNPP SDKYVTFLQS
     TIDTCYGPDT VDAILHRLRV TTDVCVAAKC LILLHKMVKS ESGYNGEDSL RNNINHRTLI
     YTQGGSNLKL NDLNVNSSRF TRELTPWVQW YKQYLDCYLS IAEVLGITPN IKEKNEDKRL
     ETQRVSSYPM DCILKQIDFL VELFEHISDR PKAPQSKLNK IVIEMTELMV QDYFSAIRLM
     RIRFEELNVR VAKPNELVPV LEKLENCKEG LSEFSWRSKY LIADFWYLVS KLKDM