ID   XHLA_BACSU              Reviewed;          89 AA.
AC   P39798;
DT   01-FEB-1995, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-1995, sequence version 1.
DT   03-AUG-2022, entry version 100.
DE   RecName: Full=Protein XhlA;
GN   Name=xhlA; OrderedLocusNames=BSU12790;
OS   Bacillus subtilis (strain 168).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus.
OX   NCBI_TaxID=224308;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=168 / SO113;
RA   Krogh S., Joergensen S.T., Diderichsen B., Devine K.M.;
RL   Submitted (SEP-1994) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=168;
RX   PubMed=7921239; DOI=10.1099/13500872-140-8-1855;
RA   Longchamp P.F., Mauel C., Karamata D.;
RT   "Lytic enzymes associated with defective prophages of Bacillus subtilis:
RT   sequencing and characterization of the region comprising the N-
RT   acetylmuramoyl-L-alanine amidase gene of prophage PBSX.";
RL   Microbiology 140:1855-1867(1994).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=168;
RX   PubMed=9555893; DOI=10.1128/jb.180.8.2110-2117.1998;
RA   Krogh S., Jorgensen S.T., Devine K.M.;
RT   "Lysis genes of the Bacillus subtilis defective prophage PBSX.";
RL   J. Bacteriol. 180:2110-2117(1998).
RN   [4]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=168;
RX   PubMed=9384377; DOI=10.1038/36786;
RA   Kunst F., Ogasawara N., Moszer I., Albertini A.M., Alloni G., Azevedo V.,
RA   Bertero M.G., Bessieres P., Bolotin A., Borchert S., Borriss R.,
RA   Boursier L., Brans A., Braun M., Brignell S.C., Bron S., Brouillet S.,
RA   Bruschi C.V., Caldwell B., Capuano V., Carter N.M., Choi S.-K.,
RA   Codani J.-J., Connerton I.F., Cummings N.J., Daniel R.A., Denizot F.,
RA   Devine K.M., Duesterhoeft A., Ehrlich S.D., Emmerson P.T., Entian K.-D.,
RA   Errington J., Fabret C., Ferrari E., Foulger D., Fritz C., Fujita M.,
RA   Fujita Y., Fuma S., Galizzi A., Galleron N., Ghim S.-Y., Glaser P.,
RA   Goffeau A., Golightly E.J., Grandi G., Guiseppi G., Guy B.J., Haga K.,
RA   Haiech J., Harwood C.R., Henaut A., Hilbert H., Holsappel S., Hosono S.,
RA   Hullo M.-F., Itaya M., Jones L.-M., Joris B., Karamata D., Kasahara Y.,
RA   Klaerr-Blanchard M., Klein C., Kobayashi Y., Koetter P., Koningstein G.,
RA   Krogh S., Kumano M., Kurita K., Lapidus A., Lardinois S., Lauber J.,
RA   Lazarevic V., Lee S.-M., Levine A., Liu H., Masuda S., Mauel C.,
RA   Medigue C., Medina N., Mellado R.P., Mizuno M., Moestl D., Nakai S.,
RA   Noback M., Noone D., O'Reilly M., Ogawa K., Ogiwara A., Oudega B.,
RA   Park S.-H., Parro V., Pohl T.M., Portetelle D., Porwollik S.,
RA   Prescott A.M., Presecan E., Pujic P., Purnelle B., Rapoport G., Rey M.,
RA   Reynolds S., Rieger M., Rivolta C., Rocha E., Roche B., Rose M., Sadaie Y.,
RA   Sato T., Scanlan E., Schleich S., Schroeter R., Scoffone F., Sekiguchi J.,
RA   Sekowska A., Seror S.J., Serror P., Shin B.-S., Soldo B., Sorokin A.,
RA   Tacconi E., Takagi T., Takahashi H., Takemaru K., Takeuchi M.,
RA   Tamakoshi A., Tanaka T., Terpstra P., Tognoni A., Tosato V., Uchiyama S.,
RA   Vandenbol M., Vannier F., Vassarotti A., Viari A., Wambutt R., Wedler E.,
RA   Wedler H., Weitzenegger T., Winters P., Wipat A., Yamamoto H., Yamane K.,
RA   Yasumoto K., Yata K., Yoshida K., Yoshikawa H.-F., Zumstein E.,
RA   Yoshikawa H., Danchin A.;
RT   "The complete genome sequence of the Gram-positive bacterium Bacillus
RT   subtilis.";
RL   Nature 390:249-256(1997).
CC   -!- FUNCTION: Associated with cell lysis upon induction of PbsX.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Single-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: To B.licheniformis xpaF1 and xpaL1. {ECO:0000305}.
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DR   EMBL; Z36941; CAA85401.1; -; Genomic_DNA.
DR   EMBL; L25924; AAA22643.1; -; Genomic_DNA.
DR   EMBL; Z70177; CAA94047.1; -; Genomic_DNA.
DR   EMBL; AL009126; CAB13136.1; -; Genomic_DNA.
DR   PIR; G69730; G69730.
DR   RefSeq; NP_389162.1; NC_000964.3.
DR   RefSeq; WP_003232655.1; NZ_JNCM01000035.1.
DR   AlphaFoldDB; P39798; -.
DR   SMR; P39798; -.
DR   IntAct; P39798; 40.
DR   STRING; 224308.BSU12790; -.
DR   TCDB; 1.E.31.1.14; the spp1 holin (spp1 holin) family.
DR   PaxDb; P39798; -.
DR   PRIDE; P39798; -.
DR   EnsemblBacteria; CAB13136; CAB13136; BSU_12790.
DR   GeneID; 936210; -.
DR   KEGG; bsu:BSU12790; -.
DR   PATRIC; fig|224308.179.peg.1387; -.
DR   eggNOG; ENOG5033MX4; Bacteria.
DR   OMA; AICTGVI; -.
DR   BioCyc; BSUB:BSU12790-MON; -.
DR   Proteomes; UP000001570; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   InterPro; IPR019715; Haemolysin_XhlA.
DR   Pfam; PF10779; XhlA; 1.
PE   4: Predicted;
KW   Cell membrane; Membrane; Reference proteome; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..89
FT                   /note="Protein XhlA"
FT                   /id="PRO_0000066006"
FT   TRANSMEM        63..83
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   89 AA;  9997 MW;  E8BB53B7A3B81AEA CRC64;
     MQQEADVNVF QQDLADMKGE HKALEQRVSA LERVSDRQDQ QIMTLNEKLN KIEENTTWIK
     RTITGAIITA VSTGIIGGAI AIMYSLLQH