XKR2_SMIMA
ID XKR2_SMIMA Reviewed; 456 AA.
AC Q5GH22;
DT 11-OCT-2005, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2005, sequence version 1.
DT 25-MAY-2022, entry version 30.
DE RecName: Full=XK-related protein 2;
DE AltName: Full=X Kell blood group-related, X-linked;
GN Name=XKRX; Synonyms=XKR2, XRG2;
OS Sminthopsis macroura (Stripe-faced dunnart).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Metatheria; Dasyuromorphia; Dasyuridae; Sminthopsis.
OX NCBI_TaxID=9302;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RA Huang C.-H., Chen Y.;
RT "A superfamily of XK-related genes (XRG) widely expressed in vertebrates
RT and invertebrates.";
RL Submitted (JAN-2004) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC protein {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the XK family. {ECO:0000305}.
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DR EMBL; AY534991; AAT07389.1; -; mRNA.
DR AlphaFoldDB; Q5GH22; -.
DR PRIDE; Q5GH22; -.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR InterPro; IPR018629; XK-rel.
DR Pfam; PF09815; XK-related; 1.
PE 2: Evidence at transcript level;
KW Membrane; Transmembrane; Transmembrane helix.
FT CHAIN 1..456
FT /note="XK-related protein 2"
FT /id="PRO_0000190775"
FT TRANSMEM 40..60
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 75..95
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 105..125
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 209..229
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 276..293
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 316..336
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 356..378
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 389..409
FT /note="Helical"
FT /evidence="ECO:0000255"
SQ SEQUENCE 456 AA; 52939 MW; AC1DE6C06F45FF3D CRC64;
MRTMSRYGIT RIQESRVEVP ARPPPVQEAI CRGPKSPCRF PFSILFSTFL YCGEAASALY
MARVYQKNND FYWMTYTIVF FLVASIMDQL TLIFVHRDLA KDKPLLLFMH LILMGPLIRC
LEALIKYFEV WQKAEEEEPY VSLTRKKMFL NGQEVLLEWE VGHSVRALTM HRNAYKRMTQ
IQAFLGSVPQ LTYQLYVSLV SPEIPLGRVL LIAFALVSVT YGATLCNMLA IQIKYDDYKV
PFHAPEIICV TIWRSLEITS RLIILVLFAA TLRLKALPFF LINFVIILLE PWVRFWKSGA
QMPNNIEKNF SRVGTLVVLI SITVLYSAIN FSCWPAMQLR LADRDLVEKT QNWSHMALHY
TLRLLENIAM VLVFRFLGTR VLMNYCHTFI CVQLIVAYLI SITFMLLFYQ YLHPLRSLFS
HNLADYLHCV CCPWSSRVRS ENAESTPETQ LNRGVV