ID   XKR7_RAT                Reviewed;         580 AA.
AC   Q5GH56;
DT   11-OCT-2005, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2005, sequence version 1.
DT   03-AUG-2022, entry version 89.
DE   RecName: Full=XK-related protein 7 {ECO:0000305};
GN   Name=Xkr7 {ECO:0000312|RGD:1359224}; Synonyms=Xrg7 {ECO:0000303|Ref.1};
OS   Rattus norvegicus (Rat).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Rattus.
OX   NCBI_TaxID=10116;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RC   STRAIN=Sprague-Dawley;
RA   Huang C.-H., Chen Y.;
RT   "A superfamily of XK-related genes (XRG) widely expressed in vertebrates
RT   and invertebrates.";
RL   Submitted (JAN-2004) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000250|UniProtKB:Q5GH64};
CC       Multi-pass membrane protein {ECO:0000255}.
CC   -!- SIMILARITY: Belongs to the XK family. {ECO:0000305}.
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DR   EMBL; AY534261; AAT07110.1; -; mRNA.
DR   RefSeq; NP_001012092.1; NM_001012092.1.
DR   RefSeq; XP_008760556.1; XM_008762334.2.
DR   AlphaFoldDB; Q5GH56; -.
DR   SMR; Q5GH56; -.
DR   STRING; 10116.ENSRNOP00000012156; -.
DR   iPTMnet; Q5GH56; -.
DR   PhosphoSitePlus; Q5GH56; -.
DR   jPOST; Q5GH56; -.
DR   PaxDb; Q5GH56; -.
DR   PRIDE; Q5GH56; -.
DR   Ensembl; ENSRNOT00000012156; ENSRNOP00000012156; ENSRNOG00000009180.
DR   GeneID; 311549; -.
DR   KEGG; rno:311549; -.
DR   UCSC; RGD:1359224; rat.
DR   CTD; 343702; -.
DR   RGD; 1359224; Xkr7.
DR   eggNOG; KOG4790; Eukaryota.
DR   GeneTree; ENSGT00990000203579; -.
DR   HOGENOM; CLU_028534_1_0_1; -.
DR   InParanoid; Q5GH56; -.
DR   OMA; RRMTLYH; -.
DR   OrthoDB; 1230316at2759; -.
DR   PhylomeDB; Q5GH56; -.
DR   TreeFam; TF316454; -.
DR   PRO; PR:Q5GH56; -.
DR   Proteomes; UP000002494; Chromosome 3.
DR   Bgee; ENSRNOG00000009180; Expressed in cerebellum and 3 other tissues.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0016020; C:membrane; IBA:GO_Central.
DR   GO; GO:0005886; C:plasma membrane; ISS:UniProtKB.
DR   GO; GO:1902742; P:apoptotic process involved in development; IBA:GO_Central.
DR   GO; GO:0043652; P:engulfment of apoptotic cell; IBA:GO_Central.
DR   GO; GO:0070782; P:phosphatidylserine exposure on apoptotic cell surface; IBA:GO_Central.
DR   InterPro; IPR018629; XK-rel.
DR   Pfam; PF09815; XK-related; 1.
PE   2: Evidence at transcript level;
KW   Cell membrane; Membrane; Reference proteome; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..580
FT                   /note="XK-related protein 7"
FT                   /id="PRO_0000190791"
FT   TRANSMEM        59..79
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        89..109
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        260..280
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        303..323
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        326..346
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        355..375
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        384..404
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        415..435
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   REGION          1..28
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          470..516
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        502..516
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   580 AA;  64338 MW;  8F4907F391B4F5BE CRC64;
     MAAKSDGAAA VAGPGPEGPA GADRGGAGGR GEVAAGIAGP GPVEAGCPGP RYELRDCCWV
     LCALLVFFSD GATDLWLAAS YYLQGQSTYF GLTLLFVLLP SLVVQLLSFR WFVYDYSEPT
     GTPGPAVSTK DSDIVGAAIS TKDSAVAFRT KEGSPELVPR PAPSSAGAYR RRCCRLCVWL
     LQTLVHLLQL GQVWRYLRAL YLGLQSRWRG ERLRRHFYWR MLFESADVSM LRLLETFLRS
     APQLVLQLSL LVHRGREPEL LTALSISASL VSLAWTLASY QKVLRDSRDD KRPLSYKGAV
     VQVLWHLFTI AARTLAFALF ASVYRLYFGI FIVAHWCIMT FWVIQGETDF CMSKWEEIIY
     NMVVGIIYIF CWFNVKEGRS RRRVTLYYCI VLLENAALTG FWYSSRNFST DFYSLILVCV
     VASSFALGIF FMCVYYCLLH PNGPMLGPQA PGCIFPEAPG PCGPPADAIT SPPRSLPRTT
     GAERDGAAVG GERAGTPTPP VFQVRPGLPP TPVARPLRTE GPVIRIDLPR KKYPAWDAHF
     IDRRLRKTIL ALEYSSPATP RLQYRSMGTS QELLEYETTV