ID   XKRY2_HUMAN             Reviewed;         117 AA.
AC   A2RUG3;
DT   10-JUN-2008, integrated into UniProtKB/Swiss-Prot.
DT   15-MAY-2007, sequence version 2.
DT   25-MAY-2022, entry version 66.
DE   RecName: Full=Testis-specific XK-related protein, Y-linked 2;
GN   Name=XKRY2;
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Homo.
OX   NCBI_TaxID=9606;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Mural R.J., Istrail S., Sutton G.G., Florea L., Halpern A.L., Mobarry C.M.,
RA   Lippert R., Walenz B., Shatkay H., Dew I., Miller J.R., Flanigan M.J.,
RA   Edwards N.J., Bolanos R., Fasulo D., Halldorsson B.V., Hannenhalli S.,
RA   Turner R., Yooseph S., Lu F., Nusskern D.R., Shue B.C., Zheng X.H.,
RA   Zhong F., Delcher A.L., Huson D.H., Kravitz S.A., Mouchard L., Reinert K.,
RA   Remington K.A., Clark A.G., Waterman M.S., Eichler E.E., Adams M.D.,
RA   Hunkapiller M.W., Myers E.W., Venter J.C.;
RL   Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RX   PubMed=15489334; DOI=10.1101/gr.2596504;
RG   The MGC Project Team;
RT   "The status, quality, and expansion of the NIH full-length cDNA project:
RT   the Mammalian Gene Collection (MGC).";
RL   Genome Res. 14:2121-2127(2004).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- TISSUE SPECIFICITY: Testis-specific.
CC   -!- SIMILARITY: Belongs to the XK family. {ECO:0000305}.
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DR   EMBL; CH471194; EAW69704.1; -; Genomic_DNA.
DR   EMBL; BC132883; AAI32884.2; -; mRNA.
DR   EMBL; BC132885; AAI32886.2; -; mRNA.
DR   EMBL; BC132901; AAI32902.2; -; mRNA.
DR   EMBL; BC132903; AAI32904.2; -; mRNA.
DR   RefSeq; NP_001002906.1; NM_001002906.1.
DR   RefSeq; NP_004668.2; NM_004677.2.
DR   AlphaFoldDB; A2RUG3; -.
DR   BioGRID; 114538; 1.
DR   BioGRID; 131703; 1.
DR   iPTMnet; A2RUG3; -.
DR   PhosphoSitePlus; A2RUG3; -.
DR   BioMuta; HGNC:23922; -.
DR   PRIDE; A2RUG3; -.
DR   DNASU; 9082; -.
DR   GeneID; 353515; -.
DR   GeneID; 9082; -.
DR   CTD; 353515; -.
DR   CTD; 9082; -.
DR   DisGeNET; 9082; -.
DR   GeneCards; XKRY2; -.
DR   HGNC; HGNC:23922; XKRY2.
DR   neXtProt; NX_A2RUG3; -.
DR   PharmGKB; PA38583; -.
DR   PhylomeDB; A2RUG3; -.
DR   PathwayCommons; A2RUG3; -.
DR   SignaLink; A2RUG3; -.
DR   BioGRID-ORCS; 353515; 3 hits in 135 CRISPR screens.
DR   BioGRID-ORCS; 9082; 10 hits in 158 CRISPR screens.
DR   Pharos; A2RUG3; Tdark.
DR   PRO; PR:A2RUG3; -.
DR   Proteomes; UP000005640; Unplaced.
DR   RNAct; A2RUG3; protein.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
PE   2: Evidence at transcript level;
KW   Membrane; Reference proteome; Transmembrane; Transmembrane helix.
FT   CHAIN           1..117
FT                   /note="Testis-specific XK-related protein, Y-linked 2"
FT                   /id="PRO_0000341575"
FT   TRANSMEM        12..29
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        45..65
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        72..92
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   117 AA;  12988 MW;  0EDBC6E9349353A7 CRC64;
     MFIFNSIADD IFPLISCVGA IHCNILAIRT GNDFAAIKLQ VIKLIYLMIW HSLVIISPVV
     TLAFFPASLK QGSLHFLLII YFVLLLTPWL EFSKSGTHLP SNTKNNSSMV GKYGCLS