XL3B_MOUSE
ID XL3B_MOUSE Reviewed; 226 AA.
AC Q6P205;
DT 20-JAN-2009, integrated into UniProtKB/Swiss-Prot.
DT 05-JUL-2004, sequence version 1.
DT 03-AUG-2022, entry version 105.
DE RecName: Full=X-linked lymphocyte-regulated protein 3B {ECO:0000312|MGI:MGI:109505};
GN Name=Xlr3b {ECO:0000312|MGI:MGI:109505};
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=C57BL/6J;
RX PubMed=19468303; DOI=10.1371/journal.pbio.1000112;
RA Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X.,
RA Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y.,
RA Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S.,
RA Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R.,
RA Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K.,
RA Eichler E.E., Ponting C.P.;
RT "Lineage-specific biology revealed by a finished genome assembly of the
RT mouse.";
RL PLoS Biol. 7:E1000112-E1000112(2009).
RN [2] {ECO:0000312|EMBL:AAH64787.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=C57BL/6J {ECO:0000312|EMBL:AAH64787.1};
RC TISSUE=Egg {ECO:0000312|EMBL:AAH64787.1};
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA project:
RT the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
CC -!- SIMILARITY: Belongs to the XLR/SYCP3 family. {ECO:0000255}.
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DR EMBL; BX571735; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; BC064787; AAH64787.1; -; mRNA.
DR CCDS; CCDS41009.1; -.
DR RefSeq; NP_001075112.1; NM_001081643.1.
DR RefSeq; XP_006528264.1; XM_006528201.2.
DR AlphaFoldDB; Q6P205; -.
DR SMR; Q6P205; -.
DR STRING; 10090.ENSMUSP00000099026; -.
DR MaxQB; Q6P205; -.
DR PaxDb; Q6P205; -.
DR PRIDE; Q6P205; -.
DR Ensembl; ENSMUST00000101486; ENSMUSP00000099026; ENSMUSG00000073125.
DR GeneID; 574437; -.
DR KEGG; mmu:574437; -.
DR UCSC; uc009tlh.1; mouse.
DR CTD; 574437; -.
DR MGI; MGI:109505; Xlr3b.
DR VEuPathDB; HostDB:ENSMUSG00000073125; -.
DR GeneTree; ENSGT00390000000062; -.
DR HOGENOM; CLU_107207_0_0_1; -.
DR InParanoid; Q6P205; -.
DR OMA; TDANQVK; -.
DR OrthoDB; 1426772at2759; -.
DR PhylomeDB; Q6P205; -.
DR TreeFam; TF328876; -.
DR BioGRID-ORCS; 574437; 0 hits in 35 CRISPR screens.
DR PRO; PR:Q6P205; -.
DR Proteomes; UP000000589; Chromosome X.
DR RNAct; Q6P205; protein.
DR Bgee; ENSMUSG00000073125; Expressed in pancreas and 62 other tissues.
DR Genevisible; Q6P205; MM.
DR GO; GO:0005654; C:nucleoplasm; ISO:MGI.
DR GO; GO:0000795; C:synaptonemal complex; IBA:GO_Central.
DR GO; GO:0051321; P:meiotic cell cycle; IBA:GO_Central.
DR GO; GO:0061003; P:positive regulation of dendritic spine morphogenesis; IMP:UniProtKB.
DR GO; GO:0051965; P:positive regulation of synapse assembly; IMP:UniProtKB.
DR GO; GO:0007286; P:spermatid development; IBA:GO_Central.
DR InterPro; IPR006888; XLR/SYCP3/FAM9_dom.
DR Pfam; PF04803; Cor1; 1.
PE 2: Evidence at transcript level;
KW Coiled coil; Reference proteome.
FT CHAIN 1..226
FT /note="X-linked lymphocyte-regulated protein 3B"
FT /id="PRO_0000361653"
FT REGION 1..65
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 159..210
FT /evidence="ECO:0000255"
FT COMPBIAS 16..31
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 40..65
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 226 AA; 26147 MW; 2FBFF07CC0CD290A CRC64;
MSSRKRKATD TAGRHSRMDP NLSSDDSQNP GAVAAANREV LDAGREDIIS SGTERQQARK
EKQDLVQEFE EPPNKVLQEN RERFSRIMTS SFSAMEVKIK DVLKTHCEER QKLCQDYSLQ
FTNLNRKLTS DAYKLKKHAE TLSNMFMEQQ KFIHESLTLQ KNRMKEFKSL CEKYLEKLEV
LRDSRGNSIA EELRRLIATL EIKLLMLHNQ QKTAAPPQSL LDVLFS