XLR_MOUSE
ID XLR_MOUSE Reviewed; 208 AA.
AC P05531;
DT 01-NOV-1988, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1988, sequence version 1.
DT 03-AUG-2022, entry version 121.
DE RecName: Full=X-linked lymphocyte-regulated protein PM1;
GN Name=Xlr;
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RX PubMed=3681192; DOI=10.1084/jem.166.6.1702;
RA Siegel J.N., Turner C.A., Klinman D.M., Wilkinson M., Steinberg A.D.,
RA Macleod C.L., Paul W.E., Davis M.M., Cohen D.I.;
RT "Sequence analysis and expression of an X-linked, lymphocyte-regulated gene
RT family (XLR).";
RL J. Exp. Med. 166:1702-1715(1987).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=FVB/N; TISSUE=Mammary gland;
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA project:
RT the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
CC -!- TISSUE SPECIFICITY: Expressed in lymphoid cells.
CC -!- SIMILARITY: Belongs to the XLR/SYCP3 family. {ECO:0000305}.
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DR EMBL; X07967; CAA30781.1; -; mRNA.
DR EMBL; BC005560; AAH05560.1; -; mRNA.
DR CCDS; CCDS30139.1; -.
DR PIR; S01067; S01067.
DR RefSeq; NP_001278676.1; NM_001291747.1.
DR RefSeq; NP_035855.1; NM_011725.4.
DR RefSeq; XP_011247951.1; XM_011249649.2.
DR RefSeq; XP_011247952.1; XM_011249650.1.
DR RefSeq; XP_011247953.1; XM_011249651.2.
DR AlphaFoldDB; P05531; -.
DR SMR; P05531; -.
DR STRING; 10090.ENSMUSP00000068044; -.
DR PaxDb; P05531; -.
DR PeptideAtlas; P05531; -.
DR PRIDE; P05531; -.
DR ProteomicsDB; 300187; -.
DR DNASU; 22441; -.
DR Ensembl; ENSMUST00000067763; ENSMUSP00000068044; ENSMUSG00000054626.
DR Ensembl; ENSMUST00000114810; ENSMUSP00000110458; ENSMUSG00000054626.
DR GeneID; 22441; -.
DR KEGG; mmu:22441; -.
DR UCSC; uc009tfl.2; mouse.
DR CTD; 22441; -.
DR MGI; MGI:98976; Xlr.
DR VEuPathDB; HostDB:ENSMUSG00000054626; -.
DR eggNOG; ENOG502R883; Eukaryota.
DR GeneTree; ENSGT00390000000062; -.
DR HOGENOM; CLU_101820_2_0_1; -.
DR InParanoid; P05531; -.
DR OMA; VMMETSA; -.
DR OrthoDB; 1547468at2759; -.
DR PhylomeDB; P05531; -.
DR TreeFam; TF328876; -.
DR BioGRID-ORCS; 22441; 3 hits in 39 CRISPR screens.
DR PRO; PR:P05531; -.
DR Proteomes; UP000000589; Chromosome X.
DR RNAct; P05531; protein.
DR Bgee; ENSMUSG00000054626; Expressed in placenta and 54 other tissues.
DR ExpressionAtlas; P05531; baseline and differential.
DR Genevisible; P05531; MM.
DR GO; GO:0000800; C:lateral element; ISO:MGI.
DR GO; GO:0005634; C:nucleus; ISO:MGI.
DR GO; GO:0000795; C:synaptonemal complex; IBA:GO_Central.
DR GO; GO:0051321; P:meiotic cell cycle; IBA:GO_Central.
DR GO; GO:0007286; P:spermatid development; IBA:GO_Central.
DR GO; GO:0035093; P:spermatogenesis, exchange of chromosomal proteins; ISO:MGI.
DR InterPro; IPR006888; XLR/SYCP3/FAM9_dom.
DR Pfam; PF04803; Cor1; 1.
PE 2: Evidence at transcript level;
KW Coiled coil; Reference proteome.
FT CHAIN 1..208
FT /note="X-linked lymphocyte-regulated protein PM1"
FT /id="PRO_0000223040"
FT REGION 1..43
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 122..143
FT /evidence="ECO:0000255"
FT COMPBIAS 18..39
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 208 AA; 24613 MW; 03858DAD3584D47E CRC64;
MENWDLSSDE MQDGNAPELD VIEEHNPVTR DDENANPEEV VGDTRSPVQN ILGKFEGDIN
KRLHIKRKRM ETYIKDSFKD SNVKLEQLWK TNKQERKKIN NKFCEQYITT FQKFDMDVQK
FNEEQEKSVN NYQKEQQALK LSKCSQSQTL EAIKDMHENY MEGLMNLETN NYNMLFDVDG
ELRKEMSVFK KDLMKHTLKY SSSFPSSD
