ID   XOL1_CAEBR              Reviewed;         426 AA.
AC   Q611X0; A8XPZ8;
DT   06-DEC-2005, integrated into UniProtKB/Swiss-Prot.
DT   22-SEP-2009, sequence version 2.
DT   25-MAY-2022, entry version 67.
DE   RecName: Full=XO lethal protein 1 homolog;
GN   Name=xol-1; ORFNames=CBG16879;
OS   Caenorhabditis briggsae.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC   Caenorhabditis.
OX   NCBI_TaxID=6238;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AF16;
RX   PubMed=14624247; DOI=10.1371/journal.pbio.0000045;
RA   Stein L.D., Bao Z., Blasiar D., Blumenthal T., Brent M.R., Chen N.,
RA   Chinwalla A., Clarke L., Clee C., Coghlan A., Coulson A., D'Eustachio P.,
RA   Fitch D.H.A., Fulton L.A., Fulton R.E., Griffiths-Jones S., Harris T.W.,
RA   Hillier L.W., Kamath R., Kuwabara P.E., Mardis E.R., Marra M.A.,
RA   Miner T.L., Minx P., Mullikin J.C., Plumb R.W., Rogers J., Schein J.E.,
RA   Sohrmann M., Spieth J., Stajich J.E., Wei C., Willey D., Wilson R.K.,
RA   Durbin R.M., Waterston R.H.;
RT   "The genome sequence of Caenorhabditis briggsae: a platform for comparative
RT   genomics.";
RL   PLoS Biol. 1:166-192(2003).
RN   [2]
RP   IDENTIFICATION.
RX   PubMed=12672694; DOI=10.1101/gad.1082303;
RA   Luz J.G., Hassig C.A., Pickle C., Godzik A., Meyer B.J., Wilson I.A.;
RT   "XOL-1, primary determinant of sexual fate in C. elegans, is a GHMP kinase
RT   family member and a structural prototype for a class of developmental
RT   regulators.";
RL   Genes Dev. 17:977-990(2003).
CC   -!- SIMILARITY: Belongs to the GHMP kinase family. Xol-1 subfamily.
CC       {ECO:0000305}.
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DR   EMBL; HE601001; CAP34724.2; -; Genomic_DNA.
DR   AlphaFoldDB; Q611X0; -.
DR   SMR; Q611X0; -.
DR   STRING; 6238.CBG16879; -.
DR   PRIDE; Q611X0; -.
DR   EnsemblMetazoa; CBG16879.1; CBG16879.1; WBGene00036693.
DR   WormBase; CBG16879; CBP34787; WBGene00036693; Cbr-xol-1.
DR   eggNOG; ENOG502TITU; Eukaryota.
DR   HOGENOM; CLU_607263_0_0_1; -.
DR   InParanoid; Q611X0; -.
DR   OMA; MEEDSIW; -.
DR   OrthoDB; 1822677at2759; -.
DR   Proteomes; UP000008549; Chromosome X.
DR   Gene3D; 3.30.230.10; -; 1.
DR   InterPro; IPR036554; GHMP_kinase_C_sf.
DR   InterPro; IPR020568; Ribosomal_S5_D2-typ_fold.
DR   InterPro; IPR014721; Ribosomal_S5_D2-typ_fold_subgr.
DR   InterPro; IPR015193; Xol-1_GHMP-like.
DR   InterPro; IPR015192; Xol-1_N.
DR   Pfam; PF09109; Xol-1_GHMP-like; 1.
DR   Pfam; PF09108; Xol-1_N; 1.
DR   SUPFAM; SSF54211; SSF54211; 1.
DR   SUPFAM; SSF55060; SSF55060; 1.
PE   3: Inferred from homology;
KW   Reference proteome.
FT   CHAIN           1..426
FT                   /note="XO lethal protein 1 homolog"
FT                   /id="PRO_0000156674"
FT   REGION          390..426
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        395..415
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   426 AA;  48752 MW;  693137EE756B929B CRC64;
     MDKTNFPPPI NHDFHVHKSS SLPIEEDVGD NAPGPKIVGI APHVVDKMGS LIMAVNKYCK
     ATTRVESPSK PRSAEEHIIE MADSFHGDIR RGLIRNLLRD LELTRVYRIQ ITGEHDYNGR
     ISQTAVLVAI WRSLKSFEHP YDRTFGEDCI WSNAETFYAM VKDYNFESAA KLSVLGATIF
     DNELKYFYDE KMDEDIQNPK GFRTLSSVGM LAEYDFVFVS TNLHTPKYTP ELFWDKENPK
     ARFERVKENV HYPDDNFAHQ MVYFSDRRVA STSIPPSPIV KLTHQGLHAV NRNESDLIGF
     EIQQGGFLVV LKKGVFLADH TWMIQIASKL VENDESNSLE EIYFHLLEPG KRSEEWKPNL
     LKYMDENHHA TVSLKKKTVQ FAEPIFFGLT SEEEPKNKPP SHNPKPRDPA DRSLSNDDTF
     DTASTS