ID   XPO7B_XENLA             Reviewed;        1087 AA.
AC   Q569Z2;
DT   30-MAY-2006, integrated into UniProtKB/Swiss-Prot.
DT   10-MAY-2005, sequence version 1.
DT   03-AUG-2022, entry version 53.
DE   RecName: Full=Exportin-7-B;
GN   Name=xpo7-b;
OS   Xenopus laevis (African clawed frog).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus.
OX   NCBI_TaxID=8355;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Embryo;
RG   NIH - Xenopus Gene Collection (XGC) project;
RL   Submitted (APR-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Mediates the nuclear export of proteins (cargos) with broad
CC       substrate specificity. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the exportin family. {ECO:0000305}.
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DR   EMBL; BC092245; AAH92245.1; -; mRNA.
DR   RefSeq; NP_001089345.1; NM_001095876.1.
DR   AlphaFoldDB; Q569Z2; -.
DR   SMR; Q569Z2; -.
DR   DNASU; 734395; -.
DR   GeneID; 734395; -.
DR   KEGG; xla:734395; -.
DR   CTD; 734395; -.
DR   Xenbase; XB-GENE-491342; xpo7.L.
DR   OrthoDB; 198413at2759; -.
DR   Proteomes; UP000186698; Chromosome 3L.
DR   Bgee; 734395; Expressed in testis and 19 other tissues.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0005049; F:nuclear export signal receptor activity; IEA:InterPro.
DR   GO; GO:0031267; F:small GTPase binding; IEA:InterPro.
DR   GO; GO:0006886; P:intracellular protein transport; IEA:InterPro.
DR   Gene3D; 1.25.10.10; -; 2.
DR   InterPro; IPR011989; ARM-like.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR001494; Importin-beta_N.
DR   InterPro; IPR044189; XPO4/7-like.
DR   InterPro; IPR040021; XPO7.
DR   PANTHER; PTHR12596; PTHR12596; 1.
DR   PANTHER; PTHR12596:SF11; PTHR12596:SF11; 1.
DR   Pfam; PF03810; IBN_N; 1.
DR   SMART; SM00913; IBN_N; 1.
DR   SUPFAM; SSF48371; SSF48371; 1.
DR   PROSITE; PS50166; IMPORTIN_B_NT; 1.
PE   2: Evidence at transcript level;
KW   Cytoplasm; Nucleus; Protein transport; Reference proteome; Transport.
FT   CHAIN           1..1087
FT                   /note="Exportin-7-B"
FT                   /id="PRO_0000237676"
FT   DOMAIN          30..96
FT                   /note="Importin N-terminal"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00115"
SQ   SEQUENCE   1087 AA;  123341 MW;  68612D3E0869F3DF CRC64;
     MADPVQSLAQ LEILCKQLYE TTDTSTRLQA EKALVEFTNS PECLSKCQLL LERGSSSYSQ
     LLAATCLTKL VSRSTNPLPL EQRIDIRNYV LTYLATRPKL ASFVTQALIQ LYARITKLGW
     FDSQKDDFVF RNVIGDVTRF LQDSVEYCVI GVSFLSQLTN EINQADATHP LTKHRKIASS
     FRDSALFDIF TLSCNLLKQA SGKSLLLSDE SQHDLLMQLL KLTHNCLNFD FIGTSTDESS
     DDLCTVQIPT SWRSAFLDSS TLQLFFDLYH SIPPNFTPLV LSCLVQIASV RRSLFNNAER
     AKFLSHLVDG VKRILENPQS LSDPNNYHEF CRLLARLKSN YQLGELVKVE NYPEVIRLIA
     NFTVTSLQHW EFAPNSVHYL LSLWQRLAAS VPYVKATEPH LLETYTPEVT KSYVTSRLES
     VHIILRDGLE DPLEDAGLVQ QQLDQLSTIG RCEYDKTCAL LVQLFDQSAQ TYQELLQSGS
     APSMELAVQE GRLTWLVYII GAVIGGRVSF ASTDEQDAMD GELVCRVLQL MNLTDSRLAQ
     AGNEKLELSM LSFFEQFRKI YIGDQVQKSS KLYRRLSDVL GLNDETMVLS IFIGKIITNL
     KYWGRCEPIT SKTLQLLNDL SIGYSSVRKL VKLSAVQFML NNHTSEHFSF LGINSQSNMS
     DMRCRTTFYT ALGRLLMVDL GEDEEQFSQF MMPLTAAFES LAQMFNSNNF NEQEAKRSLV
     GLVRDLRGIA FAFNAKSSFM MLFDWIYPAY MPILQRAIEL WFHDPACTTP ILKLMAELVH
     NRSQRLQFDV SSPNGILLFR ETSKMITTYG NRILTLGELP KEQLYVLKLK GISICFSVLK
     AALSGNYVNF GVFRLYGDEA LDNALQTFVK LLLSVPHSDL LDYPKLSQSY YSLLEVLTQD
     HMSFIASLEP HVIMYILSSI SEGLTALDTM VCTGCCSCLD HIVTYLFKQL SRSGKKRGAP
     PPQESERFLH IMQQHPEMIQ QMLSTVLNII IFEDCRNQWS MSRPLLGLIL LNEKYFSDLR
     SSIVSSQPPE KQQAMHLCFE NLMEGIEGNL LTKNRDRFTQ NLSAFRREVN DSMKNSSCGP
     NSNEMMS