ID   XPOT_MAGO7              Reviewed;        1027 AA.
AC   A4RMB1; G4MU88;
DT   01-JUL-2008, integrated into UniProtKB/Swiss-Prot.
DT   25-JAN-2012, sequence version 2.
DT   25-MAY-2022, entry version 85.
DE   RecName: Full=Exportin-T;
DE   AltName: Full=Exportin(tRNA);
DE   AltName: Full=Karyopherin-beta;
DE   AltName: Full=tRNA exportin;
GN   Name=LOS1; ORFNames=MGG_10127;
OS   Magnaporthe oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958) (Rice blast
OS   fungus) (Pyricularia oryzae).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC   Sordariomycetidae; Magnaporthales; Pyriculariaceae; Pyricularia.
OX   NCBI_TaxID=242507;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=70-15 / ATCC MYA-4617 / FGSC 8958;
RX   PubMed=15846337; DOI=10.1038/nature03449;
RA   Dean R.A., Talbot N.J., Ebbole D.J., Farman M.L., Mitchell T.K.,
RA   Orbach M.J., Thon M.R., Kulkarni R., Xu J.-R., Pan H., Read N.D.,
RA   Lee Y.-H., Carbone I., Brown D., Oh Y.Y., Donofrio N., Jeong J.S.,
RA   Soanes D.M., Djonovic S., Kolomiets E., Rehmeyer C., Li W., Harding M.,
RA   Kim S., Lebrun M.-H., Bohnert H., Coughlan S., Butler J., Calvo S.E.,
RA   Ma L.-J., Nicol R., Purcell S., Nusbaum C., Galagan J.E., Birren B.W.;
RT   "The genome sequence of the rice blast fungus Magnaporthe grisea.";
RL   Nature 434:980-986(2005).
CC   -!- FUNCTION: tRNA nucleus export receptor which facilitates tRNA
CC       translocation across the nuclear pore complex. Involved in pre-tRNA
CC       splicing, probably by affecting the interaction of pre-tRNA with
CC       splicing endonuclease (By similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}. Cytoplasm {ECO:0000250}.
CC       Note=Shuttles between the nucleus and the cytoplasm. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the exportin family. {ECO:0000305}.
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DR   EMBL; CM001232; EHA53969.1; -; Genomic_DNA.
DR   RefSeq; XP_003713776.1; XM_003713728.1.
DR   AlphaFoldDB; A4RMB1; -.
DR   SMR; A4RMB1; -.
DR   STRING; 318829.MGG_10127T0; -.
DR   EnsemblFungi; MGG_10127T0; MGG_10127T0; MGG_10127.
DR   GeneID; 2681738; -.
DR   KEGG; mgr:MGG_10127; -.
DR   VEuPathDB; FungiDB:MGG_10127; -.
DR   eggNOG; KOG2021; Eukaryota.
DR   HOGENOM; CLU_004414_0_1_1; -.
DR   InParanoid; A4RMB1; -.
DR   OMA; RFSPLCW; -.
DR   OrthoDB; 142520at2759; -.
DR   Proteomes; UP000009058; Chromosome 2.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0031267; F:small GTPase binding; IEA:InterPro.
DR   GO; GO:0000049; F:tRNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0008033; P:tRNA processing; IEA:UniProtKB-KW.
DR   GO; GO:0071528; P:tRNA re-export from nucleus; IEA:InterPro.
DR   Gene3D; 1.25.10.10; -; 1.
DR   InterPro; IPR011989; ARM-like.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR013598; Exportin-1/Importin-b-like.
DR   InterPro; IPR045546; Exportin-T_C.
DR   InterPro; IPR040017; XPOT.
DR   PANTHER; PTHR15952; PTHR15952; 1.
DR   Pfam; PF19282; Exportin-T; 1.
DR   Pfam; PF08389; Xpo1; 1.
DR   SUPFAM; SSF48371; SSF48371; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; Nucleus; Reference proteome; RNA-binding; Transport;
KW   tRNA processing; tRNA-binding.
FT   CHAIN           1..1027
FT                   /note="Exportin-T"
FT                   /id="PRO_0000343097"
SQ   SEQUENCE   1027 AA;  114818 MW;  0FB9095EDDF64D02 CRC64;
     MDAQIENAIQ IAWDPQSDPS LKSQAFEFLQ QLRADPSAWH ICSTLFTKSP RSADVVRLVS
     LEIVNLAVQV QQLDAASLAF LKDSLLDYVR RTYGPGAQDE PDVPSLQNKL TQTLTYLFAR
     LYKSGWETFL SDFLALTASS EGNPRQRDNV RGVTLYLRIL GSVHDEIADN MLARQGNEGK
     RNAELKDAIR ERDMRMVVES WQDLLSQYTG RDDAILEHTL KVMAKWVSWI DISLVITQDM
     LNLLFPLIGC VNPQGGADMV RDAAIEAFTE IAGKKMKPVD KTELISFLNL RQIISELVAS
     PPLSQFRGTH RYDSDLAESV AKLVNVVVTD VVKVLEDGSV GEESRAKAGQ HLQDFLPLLL
     RLFSDEYDEV CSTVIPSLTD ILTFLRKVPE LPDSYREMLR PIMDAIVAKM RFDETSHWFE
     GEEAEEEADF LELRKRLQNL QKSVAAVDEN LFIDVMSNLV ATTLQNLDER GAQMDWRDID
     LALHELLQFG ELALPNQGLA AKSQPSSNAA ERLNVIMRKL VESSIADFPH PAVLLQYMEV
     CVRYCVFFET NHSYIPRVLE NFVRLVHYDL TRFRVRSWYL FHRFVKQLRA QVGNVAETII
     QSIADLLPIK AEVSAEDGSE DDMSSDQTDN SADAIFNSQL YLFEAIGYIS STSATPVDKQ
     ALYARSVMEP LFRDMENHLE KAKSGDAQAI LQIHHVIMAL GTLAHGFGDH AKPGHQRQAP
     DKLVSAEFAR AAEAILIALG QLNSRMDIRA ACRSAFSKLL NVLGSAVLPQ LPQWIEGLLS
     QSSSKDEMAM FLRLLDQVVY GFKTEISDVL NLLLTPLLQR VFGGLAEPIN GTDDEIQLGE
     LRREYLTFLQ IILDNDLGAV LVSETNQGFF ESIISSVVTL AKTGGHVNMV ASRLAFCTLY
     RIVGVWGGPD VANISANPSA PTGTPTPAIP GFDQFMIERF HPVCFEVLQD PQFNPSKDAQ
     SKQVLNEIAA LEQAIYVKTG NSFISHLQSS LFPALGIDGT EFLRCMTTST DKKTFGNYLQ
     NLIKNRR